Evaluation of Genetic Polymorphisms of the Antioxidant Enzymes and Biomarkers of Oxidative Stress in Preterm Neonates With Respiratory Distress Syndrome Receiving External Surfactant [0.03%]
接受外源性肺表面活性物质治疗的早产新生儿抗氧化酶基因多态性和氧化应激生物标志物的评估
Kannan Sridharan,Mona Al Jufairi,Aamal AbdulGhani Mahdi Hejab et al.
Kannan Sridharan et al.
Background: Preterm neonates, particularly extremely preterm, are susceptible to respiratory distress syndrome (RDS) due to surfactant deficiency. Single nucleotide polymorphisms (SNPs) in the antioxidant enzymes influenc...
The Prognostic Value of Lung Injury and Fibrosis Markers, KL-6, TGF-β1, FGF-2 in COVID-19 Patients [0.03%]
COVID-19患者肺损伤和纤维化标志物KL-6，TGF-β1，FGF-2的预后价值
Hazan Karadeniz,Aslıhan Avanoğlu Güler,Hasan Selçuk Özger et al.
Hazan Karadeniz et al.
Background: Biomarkers of lung injury and interstitial fibrosis give insight about the extent of involvement and prognosis in well-known interstitial lung diseases (ILD). Serum Krebs von den Lungen-6 (KL-6) reflects direc...
MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation [0.03%]
来源于尤文肉瘤的细胞外囊泡的MicroRNA含量具有生物标志物潜力并识别了以前未报道过的EWS-FLI1位点易位
Jennifer Crow,Glenson Samuel,Emily Farrow et al.
Jennifer Crow et al.
Objective: Ewing Sarcoma Family of Tumors (ESFT) are a highly aggressive pediatric bone and soft tissue malignancy with poor outcomes in the refractory and recurrent setting. Over 90% of Ewing Sarcoma (ES) tumors are driven by the pathognom...
Monitoring of Post-Brain Injuries By Measuring Plasma Levels of Neuron-Derived Extracellular Vesicles [0.03%]
通过测量神经源性细胞外囊泡的血浆水平监测脑损伤后遗症
Naoshi Hotta,Takahiro Tadokoro,John Henry et al.
Naoshi Hotta et al.
Background: Extracellular vesicles (EV) released from neurons into the blood can reflect the state of nervous tissue. Measurement of neuron derived EV (NDE) may serve as an indicator of brain injury. ...
Renata Valente Lisboa,Fabiola Reis de Oliveira,Thaise Oliveira Quaresma et al.
Renata Valente Lisboa et al.
Background: Systemic lupus erythematosus (SLE) is a chronic, multi phenotypic, autoimmune inflammatory disease and renal involvement significantly worsens its prognosis. Apoptosis dysregulation plays a key pathogenic role...
FRailty and Arterial stiffness - the role of oXidative stress and Inflammation (FRAXI study) [0.03%]
老年动脉僵硬度与氧化应激和炎症之间的关系研究项目（FRAXI 研究）
Ekow Mensah,Khalid Ali,Winston Banya et al.
Ekow Mensah et al.
Objective: There is an association between frailty and arterial stiffness. However, arterial stiffness does not uniformly correlate with the spectrum of frailty states. Both oxidative stress and inflammaging contribute to...
Glycerophosphoinositol is Elevated in Blood Samples From CLN3 Δex7-8 pigs, Cln3 Δex7-8 Mice, and CLN3-Affected Individuals [0.03%]
CLN3 Δex7-8猪，Cln3 Δex7-8小鼠和CLN3病患者血液样本中的甘油磷肌醇升高
Jon J Brudvig,Vicki J Swier,Tyler B Johnson et al.
Jon J Brudvig et al.
Introduction: CLN3 Batten disease is a rare pediatric neurodegenerative lysosomal disorder caused by biallelic disease-associated variants in CLN3. Despite decades of intense research, specific biofluid biomarkers of dise...
Serum ACE2 Level is Associated With Severe SARS-CoV-2 Infection: A Cross-Sectional Observational Study [0.03%]
血清ACE2水平与严重SARS-CoV-2感染的关系：一项横断面观察研究
Amjad Bani Hani,Nafez Abu Tarboush,Mo&#x;ath Bani Ali et al.
Amjad Bani Hani et al.
Objectives: Angiotensin-converting enzyme 2 (ACE2) represents the primary receptor for SARS-CoV-2 to enter endothelial cells, causing coronavirus disease of 2019 (COVID-19). In this study, we investigate the association b...
Measuring Some Oxidative Stress Biomarkers in Autistic Syrian Children and Their Siblings: A Case-Control Study [0.03%]
测量氧化应激生物标志物在叙利亚自闭症儿童及其兄弟姐妹中的水平：一项病例对照研究
Oula Nasrallah,Samar Alzeer
Oula Nasrallah
Objective: Autism Spectrum Disorder (ASD) is a common neurodevelopmental disorder whose cause remains unknown. Oxidative stress is one of the possible causes of many disorders, including neurological ones. This study aims...
High Levels of the Carcinogenic Tobacco-Specific Nitrosamine NNAL and Associated Findings in Children of Smokers: A Case Series [0.03%]
吸烟者子女体内致癌烟草特异性亚硝胺NNAL含量偏高及其相关研究：一系列病例报告
E Melinda Mahabee-Gittens,Georg E Matt,Ashley L Merianos
E Melinda Mahabee-Gittens
High levels of NNAL, the tobacco smoke exposure (TSE) biomarker of the carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), indicate future cancer risk. A prior study of smokers' children revealed NNAL levels as high as active s...