Caveat Medicus: It's Time to Re-Think Stratification, You May Not Be Helping [0.03%]
医者慎行：是时候重新思考分层了，你可能并没有帮助到患者
Ognjen Arandjelović
Ognjen Arandjelović
Background: The focus of the present Letter is on the large and seemingly fertile body of work captured under the umbrella of 'patient stratification'. Ob...
Copeptin Reflect Left Ventricular Systolic Function at Early Stage of Acute Myocardial Infarction in a Pig Model [0.03%]
copeptin反映急性心肌梗死早期阶段猪模型左室收缩功能
Wenjia Li,Wenjian Sun,Liang Lyu et al.
Wenjia Li et al.
Introduction: Measurement of biomarkers early after acute myocardial infarction (AMI) might provide a cost-effective and widely available tool to assess infarct severity, myocardial dysfunction, and clinical outcomes. We ...
The Use of Biomarkers in Pharmacovigilance: A Systematic Review of the Literature [0.03%]
药物警戒中生物标志物的应用：文献系统综述
Maribel Salas,Maxine Gossell-Williams,Priyanka Yalamanchili et al.
Maribel Salas et al.
Background: The use of biomarkers varies from disease etiognosis and diagnosis to signal detection, risk prediction, and management. Biomarker use has expanded in recent years, however, there are limited reviews on the us...
Optimizing Differentiation Protocols for Producing Dopaminergic Neurons from Human Induced Pluripotent Stem Cells for Tissue Engineering Applications: Supplementary Issue: Stem Cell Biology [0.03%]
人诱导多能干细胞分化生成多巴胺能神经元的方案优化（组织工程应用）：干细胞生物学补充期刊
Meghan Robinson,Suk-Yu Yau,Lin Sun et al.
Meghan Robinson et al.
Parkinson's disease (PD) is a neurodegenerative disorder that results when the dopaminergic neurons (DNs) present in the substantia nigra necessary for voluntary motor control are depleted, making patients with this disorder ideal candidate...
Validation of Prognostic Club Cell Secretory Protein (CC16) Cut-point in an Independent ALTA Cohort [0.03%]
预测性标志物俱乐部细胞生长因子(CC16)截断值的独立验证(来自ALTA队列)
Sultan Almuntashiri,Aaron Chase,Andrea Sikora et al.
Sultan Almuntashiri et al.
Background: Club cell secretory protein (CC16) has demonstrated utility as a lung-specific biomarker in predicting mortality in acute respiratory distress syndrome (ARDS). These findings have been observed in pre-clinical...
What is the Diagnostic Accuracy of Novel Urine Biomarkers for Urinary Tract Infection? [0.03%]
新型尿液生物标志物诊断泌尿系统感染的准确性如何？
George Edwards,Anna Seeley,Adam Carter et al.
George Edwards et al.
Background: Urinary tract infection (UTI) affects half of women at least once in their lifetime. Current diagnosis involves urinary dipstick and urine culture, yet both methods have modest diagnostic accuracy, and cannot ...
Advantages and Limitations of Monitoring Circulating Tumor DNA Levels to Predict the Prognosis of Patients Diagnosed With Gastric Cancer [0.03%]
监测循环肿瘤DNA水平预测胃癌患者预后的优缺点与局限性
Wan He,Jingxin Yang,Xiao Sun et al.
Wan He et al.
Next-generation sequencing-based genomic profiling facilitates biomarker detection by cell-free DNA (cfDNA) liquid biopsy. However, the efficiency of mutation calling and the prognostic value of cfDNA biomarkers are disputed. We investigate...
Analysis of Sex-Specific Prostanoid Production Using a Mouse Model of Selective Cyclooxygenase-2 Inhibition [0.03%]
使用选择性环氧化酶-2抑制的小鼠模型分析性别特异性前列腺素生成的过程分析
Rita K Upmacis,Wendy L Becker,Donna M Rattendi et al.
Rita K Upmacis et al.
Background: Prostanoids are a family of lipid mediators formed from arachidonic acid by cyclooxygenase enzymes and serve as biomarkers of vascular function. Prostanoid production may be different in males and females indi...
Aberrant expression of miR-138 as a novel diagnostic biomarker in systemic sclerosis [0.03%]
miR-138的异常表达作为系统性硬皮病的一种新型诊断生物标志物
Paria Bayati,Hadi Poormoghim,Nazanin Mojtabavi
Paria Bayati
Background: MicroRNAs are short nucleotide sequences that contribute to the regulation of various biological functions and therefore their roles have been investigated in many pathologic conditions such as epithelial to m...
Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank [0.03%]
目标，合作与可能性：狗老龄化项目生物库的实施
Lara Mouttham,Marta G Castelhano
Lara Mouttham
Background: Biobanks have been supporting longitudinal prospective and retrospective studies by providing standardized services for the acquisition, transport, processing, storage, and distribution of high-quality biologi...