Advantages and Limitations of Monitoring Circulating Tumor DNA Levels to Predict the Prognosis of Patients Diagnosed With Gastric Cancer [0.03%]
监测循环肿瘤DNA水平预测胃癌患者预后的优缺点与局限性
Wan He,Jingxin Yang,Xiao Sun et al.
Wan He et al.
Next-generation sequencing-based genomic profiling facilitates biomarker detection by cell-free DNA (cfDNA) liquid biopsy. However, the efficiency of mutation calling and the prognostic value of cfDNA biomarkers are disputed. We investigate...
Analysis of Sex-Specific Prostanoid Production Using a Mouse Model of Selective Cyclooxygenase-2 Inhibition [0.03%]
使用选择性环氧化酶-2抑制的小鼠模型分析性别特异性前列腺素生成的过程分析
Rita K Upmacis,Wendy L Becker,Donna M Rattendi et al.
Rita K Upmacis et al.
Background: Prostanoids are a family of lipid mediators formed from arachidonic acid by cyclooxygenase enzymes and serve as biomarkers of vascular function. Prostanoid production may be different in males and females indi...
Aberrant expression of miR-138 as a novel diagnostic biomarker in systemic sclerosis [0.03%]
miR-138的异常表达作为系统性硬皮病的一种新型诊断生物标志物
Paria Bayati,Hadi Poormoghim,Nazanin Mojtabavi
Paria Bayati
Background: MicroRNAs are short nucleotide sequences that contribute to the regulation of various biological functions and therefore their roles have been investigated in many pathologic conditions such as epithelial to m...
Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank [0.03%]
目标，合作与可能性：狗老龄化项目生物库的实施
Lara Mouttham,Marta G Castelhano
Lara Mouttham
Background: Biobanks have been supporting longitudinal prospective and retrospective studies by providing standardized services for the acquisition, transport, processing, storage, and distribution of high-quality biologi...
Evaluation of Genetic Polymorphisms of the Antioxidant Enzymes and Biomarkers of Oxidative Stress in Preterm Neonates With Respiratory Distress Syndrome Receiving External Surfactant [0.03%]
接受外源性肺表面活性物质治疗的早产新生儿抗氧化酶基因多态性和氧化应激生物标志物的评估
Kannan Sridharan,Mona Al Jufairi,Aamal AbdulGhani Mahdi Hejab et al.
Kannan Sridharan et al.
Background: Preterm neonates, particularly extremely preterm, are susceptible to respiratory distress syndrome (RDS) due to surfactant deficiency. Single nucleotide polymorphisms (SNPs) in the antioxidant enzymes influenc...
The Prognostic Value of Lung Injury and Fibrosis Markers, KL-6, TGF-β1, FGF-2 in COVID-19 Patients [0.03%]
COVID-19患者肺损伤和纤维化标志物KL-6，TGF-β1，FGF-2的预后价值
Hazan Karadeniz,Aslıhan Avanoğlu Güler,Hasan Selçuk Özger et al.
Hazan Karadeniz et al.
Background: Biomarkers of lung injury and interstitial fibrosis give insight about the extent of involvement and prognosis in well-known interstitial lung diseases (ILD). Serum Krebs von den Lungen-6 (KL-6) reflects direc...
MicroRNA Content of Ewing Sarcoma Derived Extracellular Vesicles Leads to Biomarker Potential and Identification of a Previously Undocumented EWS-FLI1 Translocation [0.03%]
来源于尤文肉瘤的细胞外囊泡的MicroRNA含量具有生物标志物潜力并识别了以前未报道过的EWS-FLI1位点易位
Jennifer Crow,Glenson Samuel,Emily Farrow et al.
Jennifer Crow et al.
Objective: Ewing Sarcoma Family of Tumors (ESFT) are a highly aggressive pediatric bone and soft tissue malignancy with poor outcomes in the refractory and recurrent setting. Over 90% of Ewing Sarcoma (ES) tumors are driven by the pathognom...
Monitoring of Post-Brain Injuries By Measuring Plasma Levels of Neuron-Derived Extracellular Vesicles [0.03%]
通过测量神经源性细胞外囊泡的血浆水平监测脑损伤后遗症
Naoshi Hotta,Takahiro Tadokoro,John Henry et al.
Naoshi Hotta et al.
Background: Extracellular vesicles (EV) released from neurons into the blood can reflect the state of nervous tissue. Measurement of neuron derived EV (NDE) may serve as an indicator of brain injury. ...
Renata Valente Lisboa,Fabiola Reis de Oliveira,Thaise Oliveira Quaresma et al.
Renata Valente Lisboa et al.
Background: Systemic lupus erythematosus (SLE) is a chronic, multi phenotypic, autoimmune inflammatory disease and renal involvement significantly worsens its prognosis. Apoptosis dysregulation plays a key pathogenic role...
FRailty and Arterial stiffness - the role of oXidative stress and Inflammation (FRAXI study) [0.03%]
老年动脉僵硬度与氧化应激和炎症之间的关系研究项目（FRAXI 研究）
Ekow Mensah,Khalid Ali,Winston Banya et al.
Ekow Mensah et al.
Objective: There is an association between frailty and arterial stiffness. However, arterial stiffness does not uniformly correlate with the spectrum of frailty states. Both oxidative stress and inflammaging contribute to...