Differentiating Latent Tuberculosis from Active Tuberculosis Through Activation Phenotypes and Chemokine Markers HLA-DR, CD38, MCP-1, and RANTES: A Systematic Review and Meta-Analysis [0.03%]
通过活化表型和趋化因子标志物HLA-DR、CD38、MCP-1和RANTES区分潜伏性结核感染与活动性结核：系统评价和meta分析
Chaimae Kadi,Narjisse Ahmadi,Anass Houdou et al.
Chaimae Kadi et al.
Background: Latent TB infection (LTBI) affects one fourth of the global population. Currently, there is an absence of an optimal strategy for distinguishing between active tuberculosis (aTB) and LTBI. While some researche...
Helicobacter pylori Seroprevalence in Rheumatoid Arthritis Patients with Interstitial Lung Disease [0.03%]
风湿性关节炎合并间质性肺病患者的幽门螺旋杆菌血清学调查研究
Shomi Oka,Takashi Higuchi,Hiroshi Furukawa et al.
Shomi Oka et al.
Background: Rheumatoid arthritis (RA) is complicated with interstitial lung disease (ILD). Gastroesophageal reflux disease is prevented by Helicobacter pylori infection and is a predisposing factor for idiopathic pulmonar...
D-Dimer in Acute Mesenteric Venous Thrombosis: A Prospective Case-Control International Multicenter Study [0.03%]
急性肠系膜静脉血栓形成患者D-二聚体水平的前瞻性病例对照多中心研究
Stefan Acosta,Annika Reintam Blaser,Alexandre Nuzzo et al.
Stefan Acosta et al.
Background: Acute mesenteric venous thrombosis (MVT) is rarely suspected as primary diagnosis in emergency departments and still carries an in-hospital mortality rate of above 20%. ...
Girum Tesfaye Kiya,Elsah Tegene Asefa,Gemeda Abebe et al.
Girum Tesfaye Kiya et al.
Despite infection and sepsis being a major public health challenge, early detection and timely management are often hindered by several factors. These includes the similarity of clinical presentations between infectious and non-infectious c...
Bladder Cancer Treatments in the Age of Personalized Medicine: A Comprehensive Review of Potential Radiosensitivity Biomarkers [0.03%]
个性化医疗时代膀胱癌放射敏感性生物标志物的研究进展
Charbel Feghaly,Rafka Challita,Hanine Bou Hadir et al.
Charbel Feghaly et al.
Bladder cancer is one of the most frequently diagnosed cancers in men. While cystectomy remains the primary treatment, advances in radiotherapy and chemotherapy have highlighted the value of bladder-preserving strategies, which can also enh...
Decreased Serum Insulin Receptor Messenger RNA Level in H. pylori IgG Seropositive Type 2 Diabetic Patients [0.03%]
幽门螺杆菌IgG阳性2型糖尿病患者血清胰岛素受体信使RNA水平降低
Emmanuel Ayitey Tagoe,Jael Acquah Appiah,Pius Agyenim Boateng et al.
Emmanuel Ayitey Tagoe et al.
Background: Helicobacter pylori (H. pylori) is a known gastro-intestinal pathogen but implicated in extra-gastric diseases. The relationship between H. pylori infection and type 2 diabetes (T2DM) remains insufficiently el...
Systematic Analysis and Insights Into the Mutation Spectrum and Ethnic Differences in ATP7B Mutations Associated With Wilson Disease [0.03%]
ATP7B基因突变的系统分析及其与肝豆状核变病相关的种族差异性
Thuan Duc Lao,Thuy Ai Huyen Le
Thuan Duc Lao
Background: ATP7B (ATPase copper transporting beta gene) is constituted of 21 exons, and codes for a 1465 amino acid. The protein of ATP7B plays an key role of copper metabolism. Many previous reports indicated that mutat...
The Chromosome Passenger Complex (CPC) Components and Its Associated Pathways Are Promising Candidates to Differentiate Between Normosensitive and Radiosensitive ATM-Mutated Cells [0.03%]
染色体乘客复合物(CPC)组分及其相关途径有望用于区分ATM突变的正常放射敏感细胞和过度放射敏感细胞
Anne Dietz,Prabal Subedi,Omid Azimzadeh et al.
Anne Dietz et al.
Background: Sensitivity to ionizing radiation differs between individuals, but there is a limited understanding of the biological mechanisms that account for these variations. One example of such mechanisms are the mutati...
D-dimer as a Predictive Biomarker of Response to Chemotherapy in Patients With Metastatic Breast Cancer [0.03%]
D-二聚体可作为转移性乳腺癌患者化疗反应预测生物标志物
Lubana Alkhoder,Maher Salamoon,Maher Saifo et al.
Lubana Alkhoder et al.
Background: Tumor-induced coagulation is widely observed in cancer patients. Moreover, it is associated with tumorigenesis, tumor progression and metastasis, by creating a proliferative and proangiogenic microenvironment....
Biomarkers From Discovery to Clinical Application: In Silico Pre-Clinical Validation Approach in the Face of Lung Cancer [0.03%]
从发现到临床应用的生物标志物：肺癌面前的体外临床上验方法
Medi Kori,Esra Gov,Kazim Yalcin Arga et al.
Medi Kori et al.
Background: Clinical biomarkers, allow better classification of patients according to their disease risk, prognosis, and/or response to treatment. Although affordable omics-based approaches have paved the way for quicker ...