Genetic Association Between Polycystic Ovary Syndrome and the APOA5 rs662799 and PLIN1 rs894160 Metabolic Variants in the Western Saudi Population: A Case-Control Study [0.03%]
遗传关联研究：在沙特西部人中PCOS与APOA5代谢变异体rs662799和PLIN1代谢变异体rs894160的病例对照研究
Sherin Bakhashab,Asma A Batarfi,Mahinar M Alhartani et al.
Sherin Bakhashab et al.
Background: Polycystic ovary syndrome (PCOS) is a common endocrinological condition affecting women of reproductive age, associated with insulin resistance and obesity. PCOS pathogenesis is complex and multifactorial, inv...
Novel Serum Proteomes Expressed from Benzene Exposure Among Gasoline Station Attendants [0.03%]
汽油站工作人员苯暴露的血清蛋白质组学研究
Chan Pattama Polyong,Sittiruk Roytrakul,Jintana Sirivarasai et al.
Chan Pattama Polyong et al.
Background: Research on the proteomes impact of benzene exposure in fuel station employees remains sparse, underscoring the need for detailed health impact assessments focusing on biomarker evaluation. ...
Association of 10 Polymorphisms in PLA2R1 and HLA DQA1 Genes with Primary Membranous Nephropathy Risk: A Meta-Analysis and a Meta-Regression [0.03%]
PLA2R1和HLA-DQA1基因多态性与原发膜性肾病发病风险关联的meta分析及meta回归分析
Tarak Dhaouadi,Awatef Riahi,Taïeb Ben Abdallah et al.
Tarak Dhaouadi et al.
Background: Although, several studies have assessed the association of the phospholipase A2 receptor (PLA2R) and HLA-DQA1 SNPs with primary membranous nephropathy (PMN), results were inconsistent and between-studies heter...
MicroRNAs in Umbilical Cord Blood and Development in Full-Term Newborns: A Prospective Study [0.03%]
新生儿脐带血中的MicroRNA与婴儿发育的关系：一项前瞻性研究
Liang-Jen Wang,Ching-Chang Tsai,How-Ran Chao et al.
Liang-Jen Wang et al.
Background: Exploring the epigenetic regulations, such as microRNA, in newborns holds significant promise for enhancing our ability to address and potentially prevent early-life developmental delays. ...
Effect of Cytokeratin-18, C-peptide, MHR, and MACK-3 Biomarkers in Metabolic Dysfunction-Associated Fatty Liver Disease After Laparoscopic Sleeve Gastrectomy [0.03%]
代谢功能障碍相关性脂肪肝病患者袖状胃切除术后的细胞角蛋白-18、C肽、MHR及MACK-3生物标志物的影响研究
Mohamed Hany,Hala M Demerdash,Anwar Ashraf Abouelnasr et al.
Mohamed Hany et al.
Background: Laparoscopic sleeve gastrectomy (LSG) has emerged as a valuable treatment for various metabolic disorders, including metabolic dysfunction-associated fatty liver disease (MAFLD) in patients with obesity. Conse...
Antonis A Manolis,Theodora A Manolis,Dimitri P Mikhailidis et al.
Antonis A Manolis et al.
Lipid-lowering therapies, particularly non-statin regimens, are underutilized as ~2/3 of patients with atherosclerotic cardiovascular (CV) disease (CVD) are not optimally managed, and do not attain target low-density lipoprotein cholesterol...
The Evolving Landscape of Biomarkers for Immune Checkpoint Blockade in Genitourinary Cancers [0.03%]
免疫检查点抑制在泌尿生殖系统肿瘤生物标志物中的演变景观
Seema Mustafa,Caroline S Jansen,Yash Jani et al.
Seema Mustafa et al.
In the past decade, immune checkpoint inhibitors (ICI) have been approved for treatment of genitourinary malignancies and have revolutionized the treatment landscape of these tumors. However, despite the remarkable success of these therapie...
Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease [0.03%]
伴与不伴并发症的2型糖尿病患者生物标志物比较分析：高血压和心血管疾病作用机制的新见解
Symeon Savvopoulos,Haralampos Hatzikirou,Herbert F Jelinek
Symeon Savvopoulos
Background: Type 2 diabetes mellitus (T2DM) are 90% of diabetes cases, and its prevalence and incidence, including comorbidities, are rising worldwide. Clinically, diabetes and associated comorbidities are identified by b...
Evaluating the Role of Methylated Circulating Tumor DNA in Combination With Pathological Prognostic Factors for Predicting Recurrence of Colorectal Cancer [0.03%]
甲基化循环肿瘤DNA联合病理预后因素在预测结直肠癌复发中的作用评估
Hiba Al Naji,Jean M Winter,Susanne K Pedersen et al.
Hiba Al Naji et al.
Background: Colorectal cancer (CRC) has a high rate of recurrence, in particular for advanced disease, but prognosis based on staging and pathology at surgery can have limited efficacy. The presence of circulating tumor D...
mRNA Expression and Methylation of the RAD51, ATM, ATR, BRCA1, and BRCA2 Genes in Gastric Adenocarcinoma [0.03%]
胃腺癌中RAD51、ATM、ATR、BRCA1和BRCA2基因的mRNA表达及甲基化情况研究
Joel Del Bel Pádua,Carolline Fontes Alves Mariano,Alexandre Todorovic Fabro et al.
Joel Del Bel Pádua et al.
Background: Immunohistochemical prognostic significance of the homologous recombination-related proteins RAD51, ATM, BRCA1, and BRCA2 is known in gastric adenocarcinoma, one of the deadliest cancers. ...