Decreased Serum Insulin Receptor Messenger RNA Level in H. pylori IgG Seropositive Type 2 Diabetic Patients [0.03%]
幽门螺杆菌IgG阳性2型糖尿病患者血清胰岛素受体信使RNA水平降低
Emmanuel Ayitey Tagoe,Jael Acquah Appiah,Pius Agyenim Boateng et al.
Emmanuel Ayitey Tagoe et al.
Background: Helicobacter pylori (H. pylori) is a known gastro-intestinal pathogen but implicated in extra-gastric diseases. The relationship between H. pylori infection and type 2 diabetes (T2DM) remains insufficiently el...
Systematic Analysis and Insights Into the Mutation Spectrum and Ethnic Differences in ATP7B Mutations Associated With Wilson Disease [0.03%]
ATP7B基因突变的系统分析及其与肝豆状核变病相关的种族差异性
Thuan Duc Lao,Thuy Ai Huyen Le
Thuan Duc Lao
Background: ATP7B (ATPase copper transporting beta gene) is constituted of 21 exons, and codes for a 1465 amino acid. The protein of ATP7B plays an key role of copper metabolism. Many previous reports indicated that mutat...
The Chromosome Passenger Complex (CPC) Components and Its Associated Pathways Are Promising Candidates to Differentiate Between Normosensitive and Radiosensitive ATM-Mutated Cells [0.03%]
染色体乘客复合物(CPC)组分及其相关途径有望用于区分ATM突变的正常放射敏感细胞和过度放射敏感细胞
Anne Dietz,Prabal Subedi,Omid Azimzadeh et al.
Anne Dietz et al.
Background: Sensitivity to ionizing radiation differs between individuals, but there is a limited understanding of the biological mechanisms that account for these variations. One example of such mechanisms are the mutati...
D-dimer as a Predictive Biomarker of Response to Chemotherapy in Patients With Metastatic Breast Cancer [0.03%]
D-二聚体可作为转移性乳腺癌患者化疗反应预测生物标志物
Lubana Alkhoder,Maher Salamoon,Maher Saifo et al.
Lubana Alkhoder et al.
Background: Tumor-induced coagulation is widely observed in cancer patients. Moreover, it is associated with tumorigenesis, tumor progression and metastasis, by creating a proliferative and proangiogenic microenvironment....
Biomarkers From Discovery to Clinical Application: In Silico Pre-Clinical Validation Approach in the Face of Lung Cancer [0.03%]
从发现到临床应用的生物标志物：肺癌面前的体外临床上验方法
Medi Kori,Esra Gov,Kazim Yalcin Arga et al.
Medi Kori et al.
Background: Clinical biomarkers, allow better classification of patients according to their disease risk, prognosis, and/or response to treatment. Although affordable omics-based approaches have paved the way for quicker ...
Exploring the Correlation Between Hypoxia, HIF1A Variants, and Breast Cancer in Different Ethnicities, and Bangladeshi Women: Through ELISA and Integrative Multi-Omics Analysis [0.03%]
探究缺氧、HIF1A变异与乳腺癌在不同人种（包括孟加拉国女性）中的相关性：通过酶联免疫吸附法和整合多组学分析
Md Shihabul Islam,Jesmin
Md Shihabul Islam
Background: Hypoxia, a condition where there is a lack of oxygen, is known to play a role in cancer progression. Objective: This study ...
Correlation Analyses Between Serum Interleukin-7, Interleukin-15 and Lactate Provide Insights Into Their Potential Roles in the Regulation of Inflammation in Elderly Septic Patients [0.03%]
血清细胞因子IL-7、IL-15与乳酸水平的相关性分析揭示其潜在的抗炎作用：老年脓毒症患者中的研究
Jingjing Zhao,Ye Zhang,Jun-Yu Wang et al.
Jingjing Zhao et al.
Background: Our previous research have identified Interleukin (IL)-7 and IL-15 as prognostic biomarkers for elderly septic patients, however, little is known about the link between the serum levels of IL-7, IL-15, and lac...
Characterization of RNA Processing Genes in Colon Cancer for Predicting Clinical Outcomes [0.03%]
结肠癌中RNA加工基因的特征鉴定及其临床预后价值
Jianwen Hu,Yingze Ning,Yongchen Ma et al.
Jianwen Hu et al.
Objective: Colon cancer is associated with multiple levels of molecular heterogeneity. RNA processing converts primary transcriptional RNA to mature RNA, which drives tumourigenesis and its maintenance. The characterisati...
Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation [0.03%]
与炎症相关的结直肠癌血浆生物标志物的质量质谱蛋白质组学特征分析研究
Víctor Urbiola-Salvador,Agnieszka Jabłońska,Dominika Miroszewska et al.
Víctor Urbiola-Salvador et al.
Background: Colorectal cancer (CRC) prognosis is determined by the disease stage with low survival rates for advanced stages. Current CRC screening programs are mainly using colonoscopy, limited by its invasiveness and hi...
Navigating the Intricacies of Tumor Heterogeneity: An Insight into Potential Prognostic Breast Cancer Biomarkers [0.03%]
探析肿瘤异质性的复杂性：潜在的乳腺癌预后生物标志物展望
Nastassia Altriche,Simone Gallant,Tanya Nadine Augustine et al.
Nastassia Altriche et al.
Breast cancer is a heterogeneous disease with diverse histological and molecular subtypes. Luminal breast tumors are the most diagnosed subtype. In luminal breast cancer, hormone receptors (including ER, PR, HER2) play a diagnostic and prog...