An Overview: Genetic Tumor Markers for Early Detection and Current Gene Therapy Strategies [0.03%]
遗传肿瘤标志物与基因治疗策略概述
Reeshan Ul Quraish,Tetsuyuki Hirahata,Afraz Ul Quraish et al.
Reeshan Ul Quraish et al.
Genomic instability is considered a fundamental factor involved in any neoplastic disease. Consequently, the genetically unstable cells contribute to intratumoral genetic heterogeneity and phenotypic diversity of cancer. These genetic alter...
Decision Support System and Web-Application Using Supervised Machine Learning Algorithms for Easy Cancer Classifications [0.03%]
基于监督机器学习算法的决策支持系统和网络应用促进癌症分类
K Chandrashekar,Anagha S Setlur,Adithya Sabhapathi C et al.
K Chandrashekar et al.
Using a decision support system (DSS) that classifies various cancers provides support to the clinicians/researchers to make better decisions that can aid in early cancer diagnosis, thereby reducing chances of incorrect disease diagnosis. T...
Prevalence of Breast Cancer Subtypes Among Different Ethnicities and Bangladeshi Women: Demographic, Clinicopathological, and Integrated Cancer Informatics Analysis [0.03%]
不同族裔和孟加拉妇女乳腺癌亚型的流行率：人口统计学，临床病理学和综合癌症信息化分析
Diganta Islam,Md Shihabul Islam,Sanjida Islam Dorin et al.
Diganta Islam et al.
Background: The molecular subtyping of breast cancer is related to estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). The present study aimed to systematically analyze...
Immunogenetic Profiles and Associations of Breast, Cervical, Ovarian, and Uterine Cancers [0.03%]
乳腺癌、宫颈癌、卵巢癌和子宫体癌的免疫遗传学特征及其关联性
Lisa M James,Apostolos P Georgopoulos
Lisa M James
It is increasingly recognized that the human immune response influences cancer risk, progression, and survival; consequently, there is growing interest in the role of human leukocyte antigen (HLA), genes that play a critical role in initiat...
Visualization and Quantification of the Association Between Breast Cancer and Cholesterol in the All of Us Research Program [0.03%]
全美研究计划中胆固醇与乳腺癌之间关联的可视化和量化
Jianglin Feng,Esteban Astiazaran Symonds,Jason H Karnes
Jianglin Feng
Epidemiologic evidence for the association of cholesterol and breast cancer is inconsistent. Several factors may contribute to this inconsistency, including limited sample sizes, confounding effects of antihyperlipidemic treatment, age, and...
Identifying the Therapeutic and Prognostic Role of the CD8+ T Cell-Related Gene ALDH2 in Head and Neck Squamous Cell Carcinoma [0.03%]
CD8+ T细胞相关基因ALDH2在头颈鳞状细胞癌治疗和预后中的作用识别
Hongmei Zhang,Zhaozheng Li,Yan Zheng
Hongmei Zhang
Head and neck squamous cell carcinoma (HNSC) is a widely known malignancy which is usually diagnosed late and has a poor prognosis. This study focuses on finding a new gene linked with CD8+ T cell infiltration as a prognostic marker for pat...
TULIP: An RNA-seq-based Primary Tumor Type Prediction Tool Using Convolutional Neural Networks [0.03%]
TULIP：一个利用卷积神经网络基于RNA序列预测原发肿瘤类型的工具
Sara Jones,Matthew Beyers,Maulik Shukla et al.
Sara Jones et al.
Background: With cancer as one of the leading causes of death worldwide, accurate primary tumor type prediction is critical in identifying genetic factors that can inhibit or slow tumor progression. There have been effort...
Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues [0.03%]
单细胞转录组分析显示寄生颗粒在骨肉瘤组织中的表达
Emel Rothzerg,Wenyu Feng,Dezhi Song et al.
Emel Rothzerg et al.
Nuclear paraspeckles are subnuclear bodies contracted by nuclear-enriched abundant transcript 1 (NEAT1) long non-coding RNA, localised in the interchromatin space of mammalian cell nuclei. Paraspeckles have been critically involved in tumou...
In Silico Modeling Demonstrates that User Variability During Tumor Measurement Can Affect In Vivo Therapeutic Efficacy Outcomes [0.03%]
计算模拟显示在肿瘤测量过程中用户的变化会影响体内治疗效果
Jake T Murkin,Hope E Amos,Daniel W Brough et al.
Jake T Murkin et al.
User measurement bias during subcutaneous tumor measurement is a source of variation in preclinical in vivo studies. We investigated whether this user variability could impact efficacy study outcomes, in the form of the false negative resul...
Integration of Artificial Intelligence and CRISPR/Cas9 System for Vaccine Design [0.03%]
人工智能与CRISPR/Cas9系统在疫苗设计中的整合
Elham Maserat
Elham Maserat
The CRISPR/Cas9 system offers a new approach to genome editing and cancer treatment. This approach is able to detect drug targets and genomic analysis of cancer. The use of artificial intelligence (AI) capacity to edit genomes through CRISP...