Multi-omics Pathways Workflow (MOPAW): An Automated Multi-omics Workflow on the Cancer Genomics Cloud [0.03%]
多组学途径工作流(MOPAW):癌症基因组云上的自动化多组学工作流
Trinh Nguyen,Xiaopeng Bian,David Roberson et al.
Trinh Nguyen et al.
Introduction: In the era of big data, gene-set pathway analyses derived from multi-omics are exceptionally powerful. When preparing and analyzing high-dimensional multi-omics data, the installation process and programing ...
Chemical Complementarity of Breast Cancer Resident, T-Cell Receptor CDR3 Domains and the Cancer Antigen, ARMC3, is Associated With Higher Levels of Survival and Granzyme Expression [0.03%]
乳腺癌驻留T细胞受体CDR3区域和癌症抗原ARMC3的化学互补性与更高的生存率和颗粒酶表达水平相关
Nagehan Pakasticali,Andrea Chobrutskiy,Dhruv N Patel et al.
Nagehan Pakasticali et al.
Introduction: One of the most pressing goals for cancer immunotherapy at this time is the identification of actionable antigens. Methods: ...
Development of an eHealth Tool for Capturing and Analyzing the Immune-related Adverse Events (irAEs) in Cancer Treatment [0.03%]
一种用于捕获和分析癌症治疗中免疫相关不良事件的电子健康工具的发展
Saeed Moradian,Shive Ghasemi,Babak Boutorabi et al.
Saeed Moradian et al.
Introduction: Immunotherapy has revolutionized the treatment of many different types of cancer, but it is associated with a myriad of immune-related adverse events (irAEs). Patient-reported outcome (PRO) measures have bee...
A Real-World Study of Safety, Immunogenicity and Efficacy of Bevacizumab in Patients With Solid Malignancies: A Phase IV, Post-Marketing Study in India [0.03%]
贝伐珠单抗治疗实体瘤患者真实世界安全性、免疫原性及疗效研究:印度上市后监测IV期研究
Shubhadeep D Sinha,Ghanashyam Biswas,Bala Reddy Bheemareddy et al.
Shubhadeep D Sinha et al.
Objective: The aim of this study was to evaluate the post-marketing safety, tolerability, immunogenicity and efficacy of Bevacizumab (manufactured by Hetero Biopharma) in a broader population of patients with solid tumors...
Melanoma and Human Leukocyte Antigen (HLA): Immunogenicity of 69 HLA Class I Alleles With 11 Antigens Expressed in Melanoma Tumors [0.03%]
黑色素瘤与人类白细胞抗原(HLA):具有11种黑素瘤肿瘤表达抗原的69种HLAⅠ类等位基因的免疫原性
Apostolos P Georgopoulos,Lisa M James,Spyros A Charonis et al.
Apostolos P Georgopoulos et al.
Host immunogenetics play a critical role in the human immune response to melanoma, influencing both melanoma prevalence and immunotherapy outcomes. Beneficial outcomes that stimulate T cell response hinge on binding affinity and immunogenic...
Patient Identification and Tumor Identification Management: Quality Program in a Cancer Multicentric Clinical Data Warehouse [0.03%]
基于癌症多中心临床数据仓库的质量项目:病人及肿瘤身份识别管理
Karine Pallier,Olivier Prot,Simone Naldi et al.
Karine Pallier et al.
Background: The Regional Basis of Solid Tumor (RBST), a clinical data warehouse, centralizes information related to cancer patient care in 5 health establishments in 2 French departments. ...
Prevalence of Iron Deficiency and its Association With Breast Cancer in Premenopausal Compared to Postmenopausal Women in Al Ahsa, Saudi Arabia [0.03%]
沙特阿拉伯阿赫萨地区经产和未产妇缺铁的患病率及其与乳腺癌的关系
Mohammad Al Khamees,Aymen A Alqurain,Abdulmonem A Alsaleh et al.
Mohammad Al Khamees et al.
Iron is an essential cofactor needed for normal functions of various enzymes and its depletion lead to increase DNA damage, genomic instability, deteriorate innate, adaptive immunity, and promote tumor development. It is also linked to tumo...
Nourhan Abu-Shahba,Elsayed Hegazy,Faiz M Khan et al.
Nourhan Abu-Shahba et al.
Abnormal miRNA expression has been evidenced to be directly linked to HCC initiation and progression. This study was designed to detect possible prognostic, diagnostic, and/or therapeutic miRNAs for HCC using computational analysis of miRNA...
Quantifying the Contributions of Environmental Factors to Prostate Cancer and Detecting Risk-Related Diet Metrics and Racial Disparities [0.03%]
量化环境因素在前列腺癌中的贡献及检测与风险相关的饮食指标和种族差异
Wensheng Zhang,Kun Zhang
Wensheng Zhang
The relevance of nongenetic factors to prostate cancer (PCa) has been elusive. We aimed to quantify the contributions of environmental factors to PCa and identify risk-related diet metrics and relevant racial disparities. We performed a uni...
Trends in Subcutaneous Tumour Height and Impact on Measurement Accuracy [0.03%]
皮下肿瘤厚度变化及对测量精度影响的趋势分析
Daniel Brough,Hope Amos,Karl Turley et al.
Daniel Brough et al.
Tumour volume is typically calculated using only length and width measurements, using width as a proxy for height in a 1:1 ratio. When tracking tumour growth over time, important morphological information and measurement accuracy is lost by...