Screening of Important Factors in the Early Sepsis Stage Based on the Evaluation of ssGSEA Algorithm and ceRNA Regulatory Network [0.03%]
基于ssGSEA算法和ceRNA调控网络评估的早期脓毒症重要影响因素筛查
Liou Huang,Chunrong Wu,Dan Xu et al.
Liou Huang et al.
Background: Sepsis is a dysregulated host response to pathogens. Delay in sepsis diagnosis has become a primary cause of patient death. This study determines some factors to prevent septic shock in its early stage, contri...
AURKB as a Promising Prognostic Biomarker in Hepatocellular Carcinoma [0.03%]
AURKB作为肝细胞癌预后生物标志物的应用前景分析
Jingchuan Xiao,Yingai Zhang
Jingchuan Xiao
The Aurora kinases form a family of 3 genes encoding serine/threonine kinases and are involved in the regulation of cell division during the mitosis. This study was designed to investigate the prognostic role of Aurora kinases in hepatocell...
Comparison of the Gut Microbiota in Patients with Benign and Malignant Breast Tumors: A Pilot Study [0.03%]
良性与恶性乳腺肿瘤患者的肠道微生物群的对比研究：初步研究
Peidong Yang,Zhitang Wang,Qingqin Peng et al.
Peidong Yang et al.
The microbiome plays diverse roles in many diseases and can potentially contribute to cancer development. Breast cancer is the most commonly diagnosed cancer in women worldwide. Thus, we investigated whether the gut microbiota differs betwe...
Exploration of Prognostic Biomarkers of Muscle-Invasive Bladder Cancer (MIBC) by Bioinformatics [0.03%]
生物信息学探索肌侵袭性膀胱癌(MIBC)的预后生物标志物
Xianglai Xu,Yelin Wang,Sihong Zhang et al.
Xianglai Xu et al.
We aimed to discover prognostic factors of muscle-invasive bladder cancer (MIBC) and investigate their relationship with immune therapies. Online data of MIBC were obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus dat...
Identification of Conserved Pappalysin 1-Derived Circular RNA-Mediated Competing Endogenous RNA in Osteosarcoma [0.03%]
骨肉瘤中保守的Pappalysin 1来源的环状RNA介导的竞争性内源RNA的鉴定
Guang-Fu Ming,Bo-Hua Gao,Peng Chen
Guang-Fu Ming
The etiology of osteosarcoma (OS) is complex and not fully understood till now. This study aimed to identify the miRNAs, circRNAs, and genes (mRNAs) that are differentially expressed in OS cell lines to investigate the mechanism of circRNA-...
Sequence-Based Prediction of Plant Protein-Protein Interactions by Combining Discrete Sine Transformation With Rotation Forest [0.03%]
通过结合离散正弦变换与旋转森林来基于序列预测植物蛋白质相互作用
Jie Pan,Li-Ping Li,Chang-Qing Yu et al.
Jie Pan et al.
Protein-protein interactions (PPIs) in plants are essential for understanding the regulation of biological processes. Although high-throughput technologies have been widely used to identify PPIs, they are usually laborious, expensive, and s...
Compelling Evidence Suggesting the Codon Usage of SARS-CoV-2 Adapts to Human After the Split From RaTG13 [0.03%]
有说服力的证据表明SARS-CoV-2的密码子使用在与RaTG13分离后适应了人类
Yanping Zhang,Xiaojie Jin,Haiyan Wang et al.
Yanping Zhang et al.
SARS-CoV-2 needs to efficiently make use of the resources from hosts in order to survive and propagate. Among the multiple layers of regulatory network, mRNA translation is the rate-limiting step in gene expression. Synonymous codon usage u...
Biomarkers of Blood from Patients with Atherosclerosis Based on Bioinformatics Analysis [0.03%]
基于生物信息学分析的动脉粥样硬化患者血液生物标志物研究
Yongjiang Qian,Lili Zhang,Zhen Sun et al.
Yongjiang Qian et al.
Atherosclerosis is a multifaceted disease characterized by the formation and accumulation of plaques that attach to arteries and cause cardiovascular disease and vascular embolism. A range of diagnostic techniques, including selective coron...
[This corrects the article DOI: 10.1177/1176934320901721.]. © The Author(s) 2021.
Genome-Wide Phylogenetic Analysis, Expression Pattern, and Transcriptional Regulatory Network of the Pig C/EBP Gene Family [0.03%]
猪C/EBP基因家族的全基因组系统发生分析、表达模式和转录调控网络
Chaoxin Zhang,Tao Wang,Tongyan Cui et al.
Chaoxin Zhang et al.
The CCAAT/enhancer binding protein (C/EBP) transcription factors (TFs) regulate many important biological processes, such as energy metabolism, inflammation, cell proliferation etc. A genome-wide gene identification revealed the presence of...