Functional Annotation and Molecular Characterization of a Hypothetical Protein From Mycobacterium leprae Through In Silico Approaches: A Potential Therapeutic Target [0.03%]
基于计算方法的麻风分枝杆菌假想蛋白的功能性注解及其分子特征研究：潜在的治疗靶点
Tasnim Hosen Tanha,Shoaib Saikat,Rabiul Hasan et al.
Tasnim Hosen Tanha et al.
Objective: Mycobacterium leprae causes leprosy, an infectious disease that has persisted over centuries and is still an issue in public health in many nations. Diverse bioinformatics techniques have been effectively emplo...
Gustavo Caetano-Anollés
Gustavo Caetano-Anollés
Gene Expression Underlying Teloblast Formation in Leech (Annelida: Hirudinae) [0.03%]
钩虫（环节动物：hirudinae）teloblast形成相关的基因表达模式
Samuel Hsiao,Naim Saglam,Ralph Saunders et al.
Samuel Hsiao et al.
Objective: Species of glossiphoniid leech provide model systems for exploring fundamental questions in evolutionary and developmental biology. In this study, we took advantage of large embryonic cells and stereotypical cl...
Computational Optimization of CRISPR-Cas13a sgRNAs Targeting the SARS-CoV-2 Spike Gene for SHERLOCK-Based Diagnostics [0.03%]
基于SHERLOCK诊断的SARS-CoV-2刺突基因CRISPR-Cas13a gRNA的计算优化
Maryam Ahmadzadeh,Fatemeh Akbarian,Mohammad Hossein Sanati et al.
Maryam Ahmadzadeh et al.
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered a global health crisis, emphasizing the urgent need for accurate and rapid diagnostic tools. Modern molecular biology technologies, in...
Adaptive Evolution-Inspired Algorithm for Intrusion Detection in Bioinformatics Systems [0.03%]
受进化启发的生物信息系统入侵检测自适应算法
Mehtab Alam,Chandra Kanta Samal,Ashraf Ali et al.
Mehtab Alam et al.
The increasing integration of bioinformatics with cloud infrastructure, artificial intelligence, and real-time data analytics has introduced unprecedented cybersecurity challenges. Sensitive genomic and clinical data, when exposed to evolvi...
Comparative Genome Analysis of 25 Sri Lankan Leptospir a Isolates Outer Membrane Receptors That Interact With Human TLR2 [0.03%]
斯里兰卡25株致病性钩端螺旋体外膜与TLR2相互作用的受体蛋白比较基因组分析
Chamila Kappagoda,Indika Senavirathna,Dinesha Jayasundara et al.
Chamila Kappagoda et al.
Background: During leptospiral infection, the host innate immune response is initiated through recognition of pathogen-associated molecular patterns (PAMPs) by Toll-like receptor 2 (TLR2). Among these PAMPs, LipL32, Loa22...
Structural and Functional Characterization of a Putative Type VI Secretion System Protein in Cronobacter sakazakii as a Potential Therapeutic Target: A Computational Study [0.03%]
计算研究：肠杆菌素萨克扎基辅菌潜在的治疗靶标六型分泌系统假定蛋白的结构和功能表征
Nurun Nahar Akter,Md Moin Uddin,Nesar Uddin et al.
Nurun Nahar Akter et al.
Background: Cronobacter sakazakii, a foodborne pathogen with a fatality rate of 33%, is a rod-shaped, Gram-negative, non-spore-forming bacterium responsible for causing meningitis, bacteremia, and necrotizing enterocoliti...
Genome-Wide Identification and Characterization of the WRKY Gene Family and Their Associated Regulatory Elements in Fortunella hindsii [0.03%]
香圆中WRKY基因家族的全基因组鉴定与特征分析及其相关调控元件分析
Hadia Hussain,Aleena Alam,Iqra Mehar et al.
Hadia Hussain et al.
Background: The WRKY gene family is identified as one of the most prominent transcription factor families in plants and is involved in various biological processes such as metabolism, growth and development, and response ...
Phylodynamic Investigation of Yellow Fever Virus Sheds New Insight on Geographic Dispersal Across Africa [0.03%]
黄热病毒的谱系动态研究揭示了其在非洲大陆传播的新见解
Babatunde Olanrewaju Motayo,Adewale Opayele,Paul Akiniyi Akinduti et al.
Babatunde Olanrewaju Motayo et al.
Background: Molecular epidemiology has shown the presence of four genotypes circulating across Africa, a paucity of data exists regarding phylogeography of the African Yellow fever (YF) genotypes. The need to fill this ga...
In silico Characterization of a Hypothetical Protein (PBJ89160.1) from Neisseria meningitidis Exhibits a New Insight on Nutritional Virulence and Molecular Docking to Uncover a Therapeutic Target [0.03%]
链球菌属脑膜炎奈瑟菌中的假想蛋白(PBJ89160.1)的计算机表征为营养致病性提供了新的见解以及分子对接以发现治疗靶点
Israt Jahan Asha,Shipan Das Gupta,Md Murad Hossain et al.
Israt Jahan Asha et al.
Objective: Neisseria meningitidis is an encapsulated, diplococcus, kidney bean-shaped bacteria that causes bacterial meningitis. Our study hopes to advance our understanding of disease progression, the spread frequency of...