Glenn Hickey,Frank Dehne,Andrew Rau-Chaplin et al.
Glenn Hickey et al.
The subtree prune and regraft distance (d(SPR)) between phylogenetic trees is important both as a general means of comparing phylogenetic tree topologies as well as a measure of lateral gene transfer (LGT). Although there has been extensive...
Reverse conservation analysis reveals the specificity determining residues of cytochrome P450 family 2 (CYP 2) [0.03%]
反向保护分析揭示细胞色素P450家族2（CYP 2）的特异性决定残基
Tai-Sung Lee
Tai-Sung Lee
The concept of conservation of amino acids is widely used to identify important alignment positions of orthologs. The assumption is that important amino acid residues will be conserved in the protein family during the evolutionary process. ...
Detecting microsatellites in genome data: variance in definitions and bioinformatic approaches cause systematic bias [0.03%]
基因组数据中的微卫星检测：定义和生物信息学方法的变异导致系统偏差
Angelika Merkel,Neil J Gemmell
Angelika Merkel
Microsatellites are currently one of the most commonly used genetic markers. The application of bioinformatic tools has become common practice in the study of these short tandem repeats (STR). However, in silico studies can suffer from stud...
Exploring the evolutionary history of the differentially expressed genes between human populations: action of recent positive selection [0.03%]
探究人类种群差异表达基因的进化历史：近期正选择的作用
Wei Zhang,M Eileen Dolan
Wei Zhang
Though debates exist on the early human evolutionary models such as the "Out of Africa" theory, which hypothesizes that modern humans migrated from Africa to Europe about 50,000 to 100,000 years ago, Africans and Europeans were geographical...
Leonardo Mariño-Ramírez,Olivier Bodenreider,Natalie Kantz et al.
Leonardo Mariño-Ramírez et al.
Evolutionary knowledge is often used to facilitate computational attempts at gene function prediction. One rich source of evolutionary information is the relative rates of gene sequence divergence, and in this report we explore the connecti...