Sanjukta Aich,Louis T J Delbaere
Sanjukta Aich
Phosphoenolpyruvate carboxykinase (PCK) is the key enzyme to initiate the gluconeogenic pathway in vertebrates, yeast, plants and most bacteria. Nucleotide specificity divided all PCKs into two groups. All the eukaryotic mammalian and most ...
Identification of novel retroid agents in Danio rerio, Oryzias latipes, Gasterosteus aculeatus and Tetraodon nigroviridis [0.03%]
斑马鱼、刺鲤、三刺鱼和绿斑复鱼中新型逆转录酶的鉴定
Holly A Basta,Alex J Buzak,Marcella A McClure
Holly A Basta
Retroid agents are genomes that encode a reverse transcriptase (RT) and replicate or transpose by way of an RNA intermediate. The Genome Parsing Suite (GPS) is software created to identify and characterize Retroid agents in any genome datab...
Prediction of protein-protein interactions on the basis of evolutionary conservation of protein functions [0.03%]
基于蛋白质功能进化保守性预测蛋白质相互作用
Ekaterina Kotelnikova,Andrey Kalinin,Anton Yuryev et al.
Ekaterina Kotelnikova et al.
Motivation: Although a great deal of progress is being made in the development of fast and reliable experimental techniques to extract genome-wide networks of protein-protein and protein-DNA interactions, the sequencing o...
Magnus Bordewich,Simone Linz,Katherine St John et al.
Magnus Bordewich et al.
Hybridization is an important evolutionary process for many groups of species. Thus, conflicting signals in a data set may not be the result of sampling or modeling errors, but due to the fact that hybridization has played a significant rol...
Gonzalo Giribet
Gonzalo Giribet
Phylogenetic methods based on optimality criteria are highly desirable for their logic properties, but time-consuming when compared to other methods of tree construction. Traditionally, researchers have been limited to exploring tree space ...
The GC skew index: a measure of genomic compositional asymmetry and the degree of replicational selection [0.03%]
GC偏差指数：基因组组成不对称性的一种度量以及复制选择的程度
Kazuharu Arakawa,Masaru Tomita
Kazuharu Arakawa
Circular bacterial chromosomes have highly polarized nucleotide composition in the two replichores, and this genomic strand asymmetry can be visualized using GC skew graphs. Here we propose and discuss the GC skew index (GCSI) for the quant...
Selection effects on the positioning of genes and gene structures from the interplay of replication and transcription in bacterial genomes [0.03%]
复制和转录在细菌基因组中的相互作用对基因和基因结构定位的选择效应
Kazuharu Arakawa,Masaru Tomita
Kazuharu Arakawa
Bacterial chromosomes are partly shaped by the functional requirements for efficient replication, which lead to strand bias as commonly characterized by the excess of guanines over cytosines in the leading strand. Gene structures are also h...
J U Flanagan,T Huber
J U Flanagan
The ATP binding cassette containing transporters are a superfamily of integral membrane proteins that translocate a wide range of substrates. The subfamily B members include the biologically important multidrug resistant (MDR) protein and t...
Non-molecular-clock-like evolution following viral origins in homo sapiens [0.03%]
人类起源后病毒非分子钟似的进化模式
Wendy Mok,Kelly Seto,Jon Stone
Wendy Mok
Researchers routinely adopt molecular clock assumptions in conducting sequence analyses to estimate dates for viral origins in humans. We used computational methods to examine the extent to which this practice can result in inaccurate 'retr...
Interactions between SNP alleles at multiple Loci and variation in skin pigmentation in 122 Caucasians [0.03%]
122名高加索人皮肤色素变异的多个基因座上的单核苷酸多态性基因型间的相互作用
Sumiko Anno,Takashi Abe,Koichi Sairyo et al.
Sumiko Anno et al.
This study was undertaken to clarify the molecular basis for human skin color variation and the environmental adaptability to ultraviolet irradiation, with the ultimate goal of predicting the impact of changes in future environments on huma...