Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [0.03%]
基因标记、自我组织图和高级系统发育：参数分析
Derek Gatherer
Derek Gatherer
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures. The var...
Phylogenomic analysis reveals extensive phylogenetic mosaicism in the human GPCR superfamily [0.03%]
系统发育组学分析揭示了人类GPCR超家族广泛存在的谱系mosaic现象
Robin G Allaby,Mathew Woodwark
Robin G Allaby
A novel high throughput phylogenomic analysis (HTP) was applied to the rhodopsin G-protein coupled receptor (GPCR) family. Instances of phylogenetic mosaicism between receptors were found to be frequent, often as instances of correlated mos...
Characterization and evolution of the cell cycle-associated mob domain-containing proteins in eukaryotes [0.03%]
真核生物中细胞周期相关Mob结构域蛋白的鉴定与进化分析
Nicola Vitulo,Alessandro Vezzi,Giulio Galla et al.
Nicola Vitulo et al.
The MOB family includes a group of cell cycle-associated proteins highly conserved throughout eukaryotes, whose founding members are implicated in mitotic exit and co-ordination of cell cycle progression with cell polarity and morphogenesis...
Marc Thuillard
Marc Thuillard
Distance-based approaches to phylogeny use estimations of the evolutionary distance between sequences to reconstruct an evolution tree. If the evolution can be represented by an X-tree, the different sequences can be ordered so that the dis...
Underlying principles of natural selection in network evolution: systems biology approach [0.03%]
网络进化中自然选择的基本原理：系统生物学方法
Bor-Sen Chen,Wei-Sheng Wu
Bor-Sen Chen
Systems biology is a rapidly expanding field that integrates diverse areas of science such as physics, engineering, computer science, mathematics, and biology toward the goal of elucidating the underlying principles of hierarchical metaboli...
Fast genes and slow clades: comparative rates of molecular evolution in mammals [0.03%]
快基因与慢谱系——哺乳动物分子进化速率的比较研究
Olaf R P Bininda-Emonds
Olaf R P Bininda-Emonds
Although interest in the rate of molecular evolution and the molecular clock remains high, our knowledge for most groups in these areas is derived largely from a patchwork of studies limited in both their taxon coverage and the number of ge...
Gathering computational genomics and proteomics to unravel adaptive evolution [0.03%]
集合计算基因组学和蛋白质组学以解析适应性进化
Agostinho Antunes,Maria João Ramos
Agostinho Antunes
A recent editorial in PLoS Biology by MacCallum and Hill (2006) pointed out the inappropriateness of studies evaluating signatures of positive selection based solely in single-site analyses. Therefore the rising number of articles claiming ...
Simon Creer
Simon Creer
Introns are now commonly used in molecular phylogenetics in an attempt to recover gene trees that are concordant with species trees, but there are a range of genomic, logistical and analytical considerations that are infrequently discussed ...
Hedging our bets: the expected contribution of species to future phylogenetic diversity [0.03%]
未雨绸缪：预测物种对今后进化多样性贡献的期望值
Mike Steel,Aki Mimoto,Arne Ø Mooers
Mike Steel
If predictions for species extinctions hold, then the 'tree of life' today may be quite different to that in (say) 100 years. We describe a technique to quantify how much each species is likely to contribute to future biodiversity, as measu...
Xuhua Xia
Xuhua Xia
Codon adaptation index is a widely used index for characterizing gene expression in general and translation efficiency in particular. Current computational implementations have a number of problems leading to various systematic biases. I il...