In silico detection of virulence gene homologues in the human pathogen sphingomonas spp [0.03%]
链球菌属病原菌毒力基因同源物的计算机检测方法
Amr Tm Saeb,Satish Kumar David,Hissa Al-Brahim
Amr Tm Saeb
There is an ongoing debate about the clinical significance of Sphingomonas paucimobilis as a virulent bacterial pathogen. In the present study, we investigated the presence of different virulence factors and genes in Sphingomonas bacteria. ...
Functional Implications of RNA Splicing for Human Long Intergenic Noncoding RNAs [0.03%]
人类长间隔非编码RNA的RNA拼接的功能含义
Feng-Chi Chen,Chia-Lin Pan,Hsuan-Yu Lin
Feng-Chi Chen
Long intergenic noncoding RNAs (lincRNAs) have been suggested as playing important roles in human gene regulation. The majority of annotated human lincRNAs include multiple exons and are alternatively spliced. However, the connections betwe...
Evaluating the accuracy and efficiency of multiple sequence alignment methods [0.03%]
评估多种序列比对方法的准确性和效率
Muhammad Tariq Pervez,Masroor Ellahi Babar,Asif Nadeem et al.
Muhammad Tariq Pervez et al.
A comparison of 10 most popular Multiple Sequence Alignment (MSA) tools, namely, MUSCLE, MAFFT(L-INS-i), MAFFT (FFT-NS-2), T-Coffee, ProbCons, SATe, Clustal Omega, Kalign, Multalin, and Dialign-TX is presented. We also focused on the signif...
Peter W Harrison,Gregory E Jordan,Stephen H Montgomery
Peter W Harrison
With the greater availability of genetic data, large genome-wide scans for positive selection increasingly incorporate data from a range of sources. These data sets may be derived from different sequencing methods, each of which has potenti...
Evolutionary Analysis and Prediction of Peptide Vaccine Candidates for Foot-and-Mouth-Disease Virus Types A and O in Bangladesh [0.03%]
孟加拉国口蹄疫病毒A型和O型肽疫苗候选物的进化分析及预测
Samina Momtaz,Arafat Rahman,Munawar Sultana et al.
Samina Momtaz et al.
Foot-and-mouth disease (FMD), an endemic disease of cloven-hoofed animals, causes an annual economic loss of US$60-150 million in Bangladesh. There is no cross-protection among the foot-and-mouth disease virus (FMDV) serotypes and vaccinati...
Cloning and Expression Profiling of the Polycomb Gene, Retinoblastoma-related Protein from Tomato Solanum lycopersicum L [0.03%]
番茄(Solanum lycopersicum L.)Polycomb基因及视网膜母细胞瘤相关蛋白的克隆与表达分析
Zainab M Almutairi,Monther T Sadder
Zainab M Almutairi
Cell cycle regulation mechanisms appear to be conserved throughout eukaryotic evolution. One of the important proteins involved in the regulation of cell cycle processes is retinoblastoma-related protein (RBR), which is a negative regulator...
Comparative Study on Sequence-Structure-Function Relationship of the Human Short-chain Dehydrogenases/Reductases Protein Family [0.03%]
人短链脱氢酶/还原酶蛋白家族序构功能关系的比较研究
Nu Thi Ngoc Tang,Ly Le
Nu Thi Ngoc Tang
Human short-chain dehydrogenases/reductases (SDRs) protein family has been the subject of recent studies for its critical role in human metabolism. Studies also found that single nucleotide polymorphisms of the SDR protein family were respo...
Yuan Xu,Qiang Zhang,Changjun Zhou
Yuan Xu
Network motifs are overly represented as topological patterns that occur more often in a given network than in random networks, and take on some certain functions in practical biological applications. Existing methods of detecting network m...
The Comparative Genomics and Phylogenomics of Leishmania amazonensis Parasite [0.03%]
利什曼原虫（Leishmania amazonensis）的比较基因组学和系统基因组学
Diogo A Tschoeke,Gisele L Nunes,Rodrigo Jardim et al.
Diogo A Tschoeke et al.
Leishmaniasis is an infectious disease caused by Leishmania species. Leishmania amazonensis is a New World Leishmania species belonging to the Mexicana complex, which is able to cause all types of leishmaniasis infections. The L. amazonensi...
iteRates: An R Package for Implementing a Parametric Rate Comparison on Phylogenetic Trees [0.03%]
iteRates：一个在系统发育树上实现参数化速率比较的R软件包
James A Fordyce,Premal Shah,Benjamin M Fitzpatrick
James A Fordyce
Patterns of diversification rate variation detected in phylogenetic hypotheses are frequently used to infer historical, ecological, and evolutionary processes. The parametric rate comparison (PRC) is a method for detecting rate variation in...