A RESTful API for Access to Phylogenetic Tools via the CIPRES Science Gateway [0.03%]
一种通过CIPRES科学 gateway访问系统发育工具的RESTful应用编程接口
Mark A Miller,Terri Schwartz,Brett E Pickett et al.
Mark A Miller et al.
The CIPRES Science Gateway is a community web application that provides public access to a set of parallel tree inference and multiple sequence alignment codes run on large computational resources. These resources are made available at no c...
Muhammad Tariq Pervez,Masroor Ellahi Babar,Asif Nadeem et al.
Muhammad Tariq Pervez et al.
IVisTMSA is a software package of seven graphical tools for multiple sequence alignments. MSApad is an editing and analysis tool. It can load 409% more data than Jalview, STRAP, CINEMA, and Base-by-Base. MSA comparator allows the user to vi...
Extensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in Africa [0.03%]
非洲镰状细胞病与Knops血型多态性广泛基因组变异相关
Kimberley C Duru,Jenelle A Noble,Aldiouma Guindo et al.
Kimberley C Duru et al.
Sickle cell disease (SCD) is a multisystem disorder characterized by chronic hemolytic anemia, vaso-occlusive crises, and marked variability in disease severity. Patients require transfusions to manage disease complications, with complement...
Apparent microRNA-Target-specific Histone Modification in Mammalian Spermatogenesis [0.03%]
哺乳动物精子发生中的组蛋白修饰似乎具有microRNA靶特异性
Y-H Taguchi
Y-H Taguchi
Background: Epigenetics is an important mRNA expression regulator. However, how distinct epigenetic factors, such as microRNAs (miRNAs) and promoter methylation, cooperatively regulate mRNA expression is rarely discussed....
A novel approach to identify candidate prognostic factors for hepatitis C treatment response integrating clinical and viral genetic data [0.03%]
整合临床和病毒遗传数据识别肝癌治疗反应候选预后因素的新方法
Alicia Amadoz,Fernando González-Candelas
Alicia Amadoz
The combined therapy of pegylated interferon (IFN) plus ribavirin (RBV) has been for a long time the standard treatment for patients infected with hepatitis C virus (HCV). In the case of genotype 1, only 38%-48% of patients have a positive ...
Kevin Arbuckle,Amanda Minter
Kevin Arbuckle
Summary: windex is a package developed for the R statistical environment to provide novel tools for the analysis of convergent evolution. The recently described Wheatsheaf index provides quantitative measures of the stren...
Genome-Wide Characterization of miRNAs Involved in N Gene-Mediated Immunity in Response to Tobacco Mosaic Virus in Nicotiana benthamiana [0.03%]
烟草花叶病毒感染下Nicotiana benthamiana中参与N基因介导免疫的miRNA全基因组特征分析
Kangquan Yin,Yang Tang,Jinping Zhao
Kangquan Yin
microRNAs (miRNAs) are a class of endogenous small RNAs (sRNAs) that play pivotal roles in plant development, abiotic stress response, and pathogen response. miRNAs have been extensively studied in plants, but rarely in Nicotiana benthamian...
Classification of metagenomics data at lower taxonomic level using a robust supervised classifier [0.03%]
利用稳健的监督分类器在较低的分类水平上对元基因组数据进行分类
Tao Hou,Fu Liu,Yun Liu et al.
Tao Hou et al.
As more and more completely sequenced genomes become available, the taxonomic classification of metagenomic data will benefit greatly from supervised classifiers that can be updated instantaneously in response to new genomes. Currently, som...
Correction to: "In Silico Detection of Virulence Gene Homologues in the Human Pathogen Sphingomonas Spp." [0.03%]
“ Correction to: "In Silico Detection of Virulence Gene Homologues in the Human Pathogen Sphingomonas Spp. ""的更正通知：在线检测条件致病菌Sphingomonas基因同源物的毒力基因
Amr Tm Saeb,Satish Kumar David,Hissa Al-Brahim
Amr Tm Saeb
[This corrects the article on p. 229 in vol. 10, PMID: 25574122.].
Published Erratum
Evolutionary bioinformatics online. 2015 Jan 14:11:1. DOI:10.4137/EBO.S23536 2015
Computational analysis reveals a successive adaptation of multiple inositol polyphosphate phosphatase 1 in higher organisms through evolution [0.03%]
计算分析揭示了在进化过程中，肌醇磷酸盐磷酸酶1在较高生物体内的多次连续适应性变化
Surya P Kilaparty,Awantika Singh,William H Baltosser et al.
Surya P Kilaparty et al.
Multiple inositol polyphosphate phosphatase 1 (Minpp1) in higher organisms dephosphorylates InsP6, the most abundant inositol phosphate. It also dephosphorylates less phosphorylated InsP5 and InsP4 and more phosphorylated InsP7 or InsP8. Mi...