Phylogenetic Analysis Provides Insight Into the Molecular Evolution of Nociception and Pain-Related Proteins [0.03%]
系统发育分析揭示了伤害感受和疼痛相关蛋白质的分子进化特点
Rujun Zhai,Qian Wang
Rujun Zhai
Nociception and pain sensation are important neural processes in humans to avoid injury. Many proteins are involved in nociception and pain sensation in humans; however, the evolution of these proteins in animals is unknown. Here, we chose ...
Anaïs Vannutelli,Aïda Ouangraoua,Jean-Pierre Perreault
Anaïs Vannutelli
Background: G-quadruplexes (G4s) are secondary structures in DNA and RNA that impact various cellular processes, such as transcription, splicing, and translation. Due to their numerous functions, G4s are involved in many ...
Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer [0.03%]
计算机辅助发现新型可可碱衍生物作为EGFR蛋白靶向凋亡诱导剂
Ibrahim H Eissa,Reda G Yousef,Eslam B Elkaeed et al.
Ibrahim H Eissa et al.
The overexpression of the Epidermal Growth Factor Receptor (EGFR) marks it as a pivotal target in cancer treatment, with the aim of reducing its proliferation and inducing apoptosis. This study aimed at the CADD of a new apoptotic EGFR inhi...
Multi-omics Analysis of Prognostic Significance and Immune Infiltration of FASTK Family Members in Kidney Renal Clear Cell Carcinoma [0.03%]
FASTK家族成员在肾透明细胞癌预后意义和免疫浸润的多组学分析
Guanghui Zhong,Dali Wu,Haiping Chen et al.
Guanghui Zhong et al.
Objective: The Fas-activated serine/threonine kinase (FASTK) family of proteins has been recently found to be able to regulate mitochondrial gene expression post-transcriptionally. Nonetheless, there is a paucity of study...
Retrospective Phylodynamic and Phylogeographic Analysis of the Bluetongue Virus in Tunisia [0.03%]
突尼斯蓝舌病病毒的回顾性谱系发生和谱系地理学分析
Oussema Souiai,Marwa Arbi,Mariem Hanachi et al.
Oussema Souiai et al.
Bluetongue virus (BTV) is an arbovirus considered as a major threat for the global livestock economy. Since 1999, Tunisia has experienced several incursions of BTV, during which numerous cases of infection and mortality have been reported. ...
Molecular Mechanisms of the miR396b- GRF1 Module Underlying Rooting Regulation in Acer rubrum L [0.03%]
红 maple(L.)中miR396b-GRF1模块调控根系的分子机制
Manyu Zhang,Huiju Li,Huiyu Zhu et al.
Manyu Zhang et al.
Rooting and root development in Acer rubrum have important effects on overall growth. A. rubrum does not take root easily in natural conditions. In this study, the mechanisms of the miR396b-GRF1 module underlying rooting regulation in A. ru...
New Insights Into The Evolution of Chloroplast Genomes in Ochna Species (Ochnaceae, Malpighiales) [0.03%]
神秘果属叶绿体基因组的进化新见解
Nguyen Nhat Nam,Nguyen Hoang Danh,Vu Minh Thiet et al.
Nguyen Nhat Nam et al.
Ochnaceae DC. includes more than 600 species that exhibit potential values for environmental ecology, ornamental, pharmaceutical, and timber industries. Although studies on phylogeny and phytochemicals have been intensively conducted, chlor...
Utilizing In Silico Approaches to Investigate the Signaling Pathway's Crucial Function in Pennisetum glaucum Under Thermal Stress [0.03%]
利用计算机模拟方法研究热应力下虎尾草信号通路的关键作用
Faten Dhawi
Faten Dhawi
Pearl millet (Pennisetum glaucum (L.)) is a remarkable cereal crop known for its ability to thrive in challenging environmental conditions. Despite its resilience, the intricate molecular mechanisms behind its toughness remain a mystery. To...
Transposable Elements-Derived MicroRNA Expression Patterns in TCGA Dataset for 10 Species [0.03%]
TCGA数据集中的10种物种的转座子来源的microRNA表达模式
Chan-Mi Lee,Sang Woo Jin,Byunghyun Jang et al.
Chan-Mi Lee et al.
MicroRNAs (miRNAs) are a class of non-coding RNAs that act as regulators of disease. An evolutionary approach to the disease could reveal factors such as diagnosis, treatment, and prognosis prediction. The expression patterns of transposabl...
The Pan-Genomic Analysis of Corynebacterium striatum Revealed its Genetic Characteristics as an Emerging Multidrug-Resistant Pathogen [0.03%]
泛基因组分析揭示了分枝杆菌作为一种新兴的多重耐药病原体的遗传特征
Junhui Qiu,Yulan Shi,Fei Zhao et al.
Junhui Qiu et al.
Corynebacterium striatum is a Gram-positive bacterium that is straight or slightly curved and non-spore-forming. Although it was originally believed to be a part of the normal microbiome of human skin, a growing number of studies have ident...