MicroRNA Transcriptomes Reveal Prevalence of Rare and Species-Specific Arm Switching Events During Zebrafish Ontogenesis [0.03%]
微小核糖核酸转录组揭示了罕见和物种特异性臂切换事件在斑马鱼发生发育过程中的普遍存在性
Arthur Casulli de Oliveira,Luiz Augusto Bovolenta,Lucas Figueiredo et al.
Arthur Casulli de Oliveira et al.
In metazoans, microRNAs (miRNAs) are essential regulators of gene expression, affecting critical cellular processes from differentiation and proliferation, to homeostasis. During miRNA biogenesis, the miRNA strand that loads onto the RNA-in...
The Spatio-Temporal Expression Profiles of Silkworm Pseudogenes Provide Valuable Insights into Their Biological Roles [0.03%]
家蚕假基因的时空表达谱提供了其生物学功能的重要见解
Linrong Wan,Siyuan Su,Jinyun Liu et al.
Linrong Wan et al.
Background: Pseudogenes are sequences that have lost the ability to transcribe RNA molecules or encode truncated but possibly functional proteins. While they were once considered to be meaningless remnants of evolution, r...
Study on Allele Specific Expression of Long-Term Residents in High Altitude Areas [0.03%]
高原世居人群基因特异表达研究
Chao He,Bin Zhu,Wenwen Gao et al.
Chao He et al.
In diploid organisms, half of the chromosomes in each cell come from the father and half from the mother. Through previous studies, it was found that the paternal chromosome and the maternal chromosome can be regulated and expressed indepen...
An Integrated Framework for Analysis and Prediction of Impact of Single Nucleotide Polymorphism Associated with Human Diseases [0.03%]
一种分析和预测与人类疾病相关的单核苷酸多态性影响的综合框架
Syed Shah Muhammad,Muhammad Shoaib,Muhammad Tariq Pervez
Syed Shah Muhammad
Single nucleotide polymorphisms are most common type of genetic variation in human genome. Analyzing genetic variants can help us better understand the genetic basis of diseases and develop predictive models which are useful to identify ind...
HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer [0.03%]
连接肠上皮化生和胃癌的HNF4A桥梁作用
Yihang Zhao,Hong Tang,Jianhua Xu et al.
Yihang Zhao et al.
Background: Intestinal metaplasia (IM) of gastric epithelium has traditionally been regarded as an irreversible stage in the process of the Correa cascade. Exploring the potential molecular mechanism of IM is significant ...
Genomic Characterization of IS 6110 Insertions in Mycobacterium orygis [0.03%]
Mycobacterium orygis 耐药性的基因组特征分析
Ahmed Kabir Refaya,Umashankar Vetrivel,Kannan Palaniyandi
Ahmed Kabir Refaya
Mycobacterium orygis, a subspecies of the Mycobacterium tuberculosis complex (MTBC), has emerged as a significant concern in the context of One Health, with implications for zoonosis or zooanthroponosis or both. MTBC strains are characteriz...
Large-scale Pan Genomic Analysis of Mycobacterium tuberculosis Reveals Key Insights Into Molecular Evolutionary Rate of Specific Processes and Functions [0.03%]
大规模的结核分枝杆菌泛基因组分析揭示了特定过程和功能分子进化速率的关键见解
Eshan Bundhoo,Anisah W Ghoorah,Yasmina Jaufeerally-Fakim
Eshan Bundhoo
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), an infectious disease that is a major killer worldwide. Due to selection pressure caused by the use of antibacterial drugs, Mtb is characterised by mutational eve...
Draft Genome Sequence of Pantoea sp. Strain MHSD4, a Bacterial Endophyte With Bioremediation Potential [0.03%]
潘特氏菌MHSD4株的草稿基因组序列，一种具有生物修复潜能的细菌内生菌
Dimpho Michelle Morobane,Khuthadzo Tshishonga,Mahloro Hope Serepa-Dlamini
Dimpho Michelle Morobane
Pantoea sp. strain MHSD4 is a bacterial endophyte isolated from the leaves of the medicinal plant Pellaea calomelanos. Here, we report on strain MHSD4 draft whole genome sequence and annotation. The draft genome size of Pantoea sp. strain M...
A Comprehensive Analysis of 3 Moroccan Genomes Revealed Contributions From Both African and European Ancestries [0.03%]
对3个摩洛哥人基因组的全面分析揭示了来自非洲和欧洲祖先的贡献
Nasma Boumajdi,Houda Bendani,Souad Kartti et al.
Nasma Boumajdi et al.
Genetic variations in the human genome represent the differences in DNA sequence within individuals. This highlights the important role of whole human genome sequencing which has become the keystone for precision medicine and disease predic...
Screening and Validation of Key Genes of Autophagy in Acute Myocardial Infarction Based on Bioinformatics [0.03%]
基于生物信息学筛选和验证急性心肌梗死自噬的关键基因
Yingjie Geng,Yu&#x;e Han,Shujuan Wang et al.
Yingjie Geng et al.
Aims: Autophagy plays a significant role in the development of acute myocardial infarction (AMI), and cardiomyocyte autophagy is of major importance in maintaining cardiac function. We aimed to identify key genes associat...