Therapy for HIV-associated cryptococcal meningitis: a case report demonstrating a new treatment approach emphasizing updated treatment guidelines [0.03%]
HIV相关性隐球菌脑膜炎的治疗：一例报道，强调了最新的治疗指南中的新治疗方法
David M Hachey,Brian R Wood,Martha Buitrago et al.
David M Hachey et al.
Cryptococcal meningitis (CM) remains a significant global health burden, especially for persons living with HIV. Despite effective antiretroviral and antifungal therapy, mortality rates are still approximately 70% in low- and middle-income ...
Clozapine is the approved option in treatment-resistant schizophrenia and requires careful management [0.03%]
氯氮平是治疗难治性精神分裂症的首选药物，其使用需要谨慎管理
Caroline Fenton,Connie Kang
Caroline Fenton
Clozapine is the only agent approved for treatment-resistant schizophrenia, but is underprescribed. Its adverse drug event (ADE) profile and patient monitoring requirements can discourage its use, but the benefits of clozapine generally out...
Antidepressants with anti-inflammatory properties may be useful in long COVID depression [0.03%]
具有抗炎特性的抗抑郁药可能对长期COVID抑郁症有用
Caroline Fenton,Arnold Lee
Caroline Fenton
Long COVID, which is characterised by the presence of persistent symptoms following a COVID infection, may also cause long COVID depression (LCD). Although the risk factors for LCD are not directly characterised, prior mental health visits ...
Hannah A Blair
Hannah A Blair
Oral nirmatrelvir plus ritonavir (Paxlovid™) is an effective treatment option for coronavirus disease 2019 (COVID-19), the illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nirmatrelvir inhibits the main prote...
The role of professional socialisation in reducing drug-related problems during COVID-19: a new insight for future pandemics [0.03%]
职业社会化的角色在COVID-19期间减少与药物相关的问题：对未来的流行病的新见解
Ahmad Z Al Meslamani
Ahmad Z Al Meslamani
mRNA COVID-19 vaccines are well tolerated and myopericarditis is a rare adverse event following immunisation [0.03%]
mRNA新冠肺炎疫苗耐受性良好，心肌心包炎是极为罕见的接种后不良事件
Caroline Fenton,Arnold Lee
Caroline Fenton
mRNA vaccines are considered to be important tools for the management of the COVID-19 pandemic. Although mRNA COVID-19 vaccines are well tolerated in most recipients, post-marketing data have highlighted an association between myocarditis a...
RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use [0.03%]
关于RTS,S/AS01型疟疾疫苗（商品名：Mosquirix®）的使用概况
Yahiya Y Syed
Yahiya Y Syed
RTS,S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium falciparum. In a phase 3 trial, RTS,S/AS01 showed vaccine efficacy against clinical malaria, severe malaria and malaria hospitalization, with an acceptable safety an...
Design and implementation of an online tool for managing the availability of high-cost perishable medicines [0.03%]
一种用于管理高成本易腐药物可用性的在线工具的设计与实现
Myriam Gallego Galisteo,Javier Romero Puerto,Maria José Martínez Bautista et al.
Myriam Gallego Galisteo et al.
Introduction: Due to their impact on healthcare systems, the sustainability and optimization of high-cost drugs is an issue of concern for several countries. Different strategies have been implemented such as centralized ...