Molecular Subtypes Based on PANoptosis Genes and Characteristics of Immune Infiltration in Cutaneous Melanoma [0.03%]
基于PANoptosis基因的分子亚型及其免疫浸润特征在皮肤黑色素瘤中的研究
Like Zhong,Wenkang Qian,Wangang Gong et al.
Like Zhong et al.
Cutaneous melanoma (CM) remains the most life-threatening form of skin cancer. Further risk stratification and search for new prognostic targets for CM are of positive clinical significance. PANoptosis is defined as an inflammatory programm...
CRISPR/Cas-9 vector system: targets UL-39 and inhibits Simplexvirus humanalpha1 (HSV-1) replication in vitro [0.03%]
CRISPR/Cas-9载体系统：以UL-39为靶点，抑制单纯疱疹病毒1型（HSV-1）的体外复制
Jéssica Vasques Raposo,Luciana Rodrigues Carvalho Barros,Lauana Ribas Torres et al.
Jéssica Vasques Raposo et al.
Simplexvirus humanalpha1 (HSV-1) affects approximately 67% of the world's population. Here, we sought to use the CRISPR / Cas9 system with the UL39 target, essential for virus replication. The sgRNA sequence was inserted into the plasmid (PX4...
Integrated bioinformatics analysis of microarray data from non-small cell lung cancer [0.03%]
非小细胞肺癌基因芯片数据的综合生物信息学分析
Lulu Feng,Wenping Cai,Shan Jin et al.
Lulu Feng et al.
Non-small cell lung cancer (NSCLC), with its high mortality rate, lack of early diagnostic markers and prevention of distant metastases are the main challenges in treatment. To identify potential miRNAs and key genes in NSCLC to find new bi...
Saman Rafeeq Abdulla,Sarmad Raheem Kareem,Ayad H Hasan
Saman Rafeeq Abdulla
Due to its rising prevalence, first-trimester miscarriage is getting more attention. Abortion etiology and pathology, especially in non-pathological cases, are unknown. In this study, 435 vaginal swabs were collected from aborted women in M...
Maykel González Torres,Gerardo Leyva Gómez,María Luisa Del Prado-Audelo et al.
Maykel González Torres et al.
In recent years, increasing interest has been paid to using antibody-based therapies for clinical applications. However, it is unclear whether recombinant antibodies can be combined with other scientific approaches to generate innovative so...
Resveratrol alleviates MSU-induced gouty arthritis in rats through inhibition of HIF-1α- and NLRP3-derived IL-1β secretion in macrophages [0.03%]
白藜芦醇通过抑制巨噬细胞中的HIF-1α和NLRP3来源的IL-1β分泌缓解MSU诱导的急性痛风性关节炎
Yamen Wang,Wei Li,Tianhan Zhang et al.
Yamen Wang et al.
Gouty arthritis is an acute and chronic joint inflammatory joint disease characterized by the deposition of monosodium urate (MSU) crystals in joints and periarticular tissues. Resveratrol (3, 5, 4-trihydroxy-trans-stilbene, RV), a natural ...
Validation of secretory Immunoglobulin A (IgA) for early and efficient diagnosis of Pseudomonas aeruginosa lung infection [0.03%]
分泌型免疫球蛋白A(IgA)诊断铜绿假单胞菌肺部感染的有效性和高效性验证研究
Yingzhen Zhou,Hao Zhang,Poonam Verma et al.
Yingzhen Zhou et al.
Pseudomonas aeruginosa is a gram-negative bacterium that is considered to be a major causal organism of nosocomial infection. This study brought data-specific evidence to reveal the efficacy of secretory Immunoglobulin A (IgA) measurement i...
Management of Acute Cerebral Infarction by Intravenous Thrombolysis with Recombinant T Cell Receptor and Plasminogen Activator and Association of Emergency Nursing Route in the Prognosis [0.03%]
重组T细胞受体和尿激酶原联合静脉溶栓治疗急性脑梗死及急诊护理路径对其预后的影响管理
Yuqi Liu,Chengyong Wang,Yuanpeng Han
Yuqi Liu
The purpose of this study is to determine the impact and prognosis of the emergency nursing approach in conjunction with the use of recombinant T cell receptors and plasminogen activators in patients who have just had an acute stroke. In th...
Randomized Controlled Trial
Cellular and molecular biology (Noisy-le-Grand, France). 2023 Aug 31;69(8):18-24. DOI:10.14715/cmb/2023.69.8.3 2023
Colonoscopy Combined with Me-Nbi to Observe the Canceration Characteristics of Colon Polyps and the Correlation of RHOC Protein Expression [0.03%]
联合肠镜窄带成像技术观察结肠息肉癌变特征及RHOC蛋白表达的相关性研究
Shuqi Xu,Weimin Chen,Yiming Chen et al.
Shuqi Xu et al.
The current study was carried out to analyze the characteristics of colon polyps canceration observed by colonoscopy combined with ME-NBI (Magnifying Endoscopy combined with Narrow-Band Imaging) and its correlation with RhoC (Ras homolog ge...
Functional assessment of DNA extraction methods from frozen human blood samples for Sanger sequencing analysis [0.03%]
桑格测序分析中评估冻存人血样品DNA提取方法的实用性
Pravi Vidyadharan,Santhi Ckv,Anjali Sethumadhavan et al.
Pravi Vidyadharan et al.
The quality of input DNA is crucial for obtaining significant inferences from molecular techniques like Sanger sequencing and Next Generation Sequencing experiments. Many of the extraction methods are suitable for retrieving quality DNA fro...