Silencing of long non-coding RNA SDCBP2-AS1/microRNA-656-3p/CRIM1 axis promotes ferroptosis of lung cancer cells [0.03%]
长非编码RNA SDCBP2-AS1/miR-656-3p/CRIM1轴沉默通过促进肺癌细胞铁死亡来抑制肿瘤进展
Ninghuang Dai,Haitao Ma,Yu Feng
Ninghuang Dai
Long non-coding RNAs (lncRNAs) play central roles in lung cancer progression by acting as competing endogenous RNAs (ceRNAs). This study aimed to explore the roles of lncRNA SDCBP2-AS1 in lung cancer and the molecular mechanism. The express...
Downregulation of NOX4 improves airway remodeling and inflammation by the TGF-β1-Smad2/3 pathway in asthma [0.03%]
NOX4下调通过TGF-β1-Smad2/3通路改善哮喘气道重构和炎症反应
Aili Xuan,Mei Yang,Qun Xia et al.
Aili Xuan et al.
Asthma is a respiratory inflammatory disease, and nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) is involved in the progression of respiratory diseases. However, the role of NOX4 in asthma remains unclear. In the present study...
Crocin improves lower extremity deep venous thrombosis by regulating the PIM1/FOXO3a axis [0.03%]
姜黄素通过调节PIM1/FOXO3A轴改善下肢深静脉血栓形成
Jun Chen,Yi Yang,Shuo Wang et al.
Jun Chen et al.
Lower extremity deep venous thrombosis (LEDVT) has a high incidence and mortality. Crocin has the potential to ameliorate thrombosis. The study aimed to clarify whether crocin affects LEDVT. Human umbilical vein endothelial cells (HUVECs) w...
Identification of anoikis related subtypes and construction of prognostic model in hepatocellular carcinoma [0.03%]
肝癌中与anoikis相关的亚型鉴定及预后模型的构建
Wanzhi Fang,Zhong Chen
Wanzhi Fang
Anoikis resistance, the acquired ability of tumor cells to resist detachment-induced cell death, has been linked to loss of cellular homeostasis, cancer growth, and metastasis. After cancer cells acquire this ability, they can spread to oth...
Evaluating the expression level of genes related to autophagy in rheumatoid arthritis patients [0.03%]
类风湿关节炎患者自噬相关基因表达量的评估研究论文
Wen Zhao,Shengbin Shi,Ai Jian et al.
Wen Zhao et al.
Rheumatoid arthritis or joint rheumatism is the most common systemic inflammatory disease of the joints and is considered one of the chronic autoimmune diseases. T cells and other immune cells are called to the synovial tissue and cause thi...
Perindopril improves cardiac fibrosis through targeting the AngII/AT1R pathway [0.03%]
培哚普利通过作用于血管紧张素Ⅱ/AT1受体通路改善心脏纤维化
Hao Liang,Na Zhang,Le Zhao et al.
Hao Liang et al.
To uncover the potential effect of Perindopril on cardiac fibrosis caused by pressure overload and the underlying mechanism. Cardiac fibrosis model in mice was established by TAC method. Mice were assigned into sham group, TAC group, 2 mg/k...
LncRNA MEG3 promotes neuronal apoptosis in rats with ischemic cerebral infarction via the TGF-β1 pathway [0.03%]
长链非编码RNA MEG3通过TGF-β1途径促进缺血性脑梗死大鼠神经元凋亡
Shiyu Long,Jingli Chen,Shuwei Tan et al.
Shiyu Long et al.
To study the influence of long non-coding ribonucleic acid maternally expressed gene 3 (lncRNA MEG3) on the neuronal apoptosis in rats with ischemic cerebral infarction, and to analyze its regulatory effect on the transforming growth factor...
In-vivo anti-inflammatory effects of Roman Chamomile (Chamaemelum nobile) aqueous extracts collected from the National Park of El-Kala (North-East, Algeria) [0.03%]
罗马洋甘菊（Chamaemelum nobile）水提取物的体内抗炎作用
Mustapha Hichem Zadam,Meriem Ahmida,Nesrine Djaber et al.
Mustapha Hichem Zadam et al.
The aim of our study is to evaluate anti-inflammatory effect of Chamaemelum nobile. Aqueous extracts were administrated to Wistar rats in bronchial-inflammation experimentally induced by an allergen and ovalbumin, administered intraperitone...
Nobiletin regulates invasion, migration and metastasis in hypopharyngeal squamous cell carcinoma [0.03%]
新橙皮苷二氢查尔酮调节低咽部鳞状细胞癌的侵袭、迁移和转移作用
Marisol Rosas-Martínez,José Antonio González Rosales,Gloria Gutiérrez-Venegas
Marisol Rosas-Martínez
Head and neck squamous cell carcinoma carries a poor prognosis. Patients typically present with advanced disease and exhibit severe malnutrition at the time of diagnosis. Nobiletin (NOB) (5,6,7,8,3',4'-Hexamethoxyflavone) is a polymethoxyfl...
The linkage between microRNA and cancer and its delivery as cancer therapy: A mini-review [0.03%]
微小核糖核酸与癌症的关联及其作为癌症治疗方法的作用：综述
Syed Umar Faruq Syed Najmuddin,Ammar Akram Kamarudin,Suraya Abdul Sani et al.
Syed Umar Faruq Syed Najmuddin et al.
The central dogma of molecular biology was no longer "central" after ground-breaking discoveries conveyed gene expression involves more complex physiological functions in cancer pathogenesis over the last decade. MicroRNAs (miRNAs) are shor...