Effects of respiratory flora regulation on microbial environment and IL-10/STAT3 signaling pathway in the bronchiolitis obliterans after lung transplantation [0.03%]
调节呼吸道菌群对肺移植后支气管腔外狭窄的影响及其作用机制研究
Xin Wang,Tianhua Liu,Yizhuo Chen et al.
Xin Wang et al.
Our purpose of this study was to explore the application effect of respiratory flora regulation in bronchiolitis obliterans after lung transplantation, and its regulatory effect on the microbial environment of the lesion and the IL-10/STAT3...
Synergistic toxicity of some food additives used in non-alcoholic beverages on renal tubular epithelial cells [0.03%]
几种非酒精饮料中所用食品添加剂对肾小管上皮细胞的协同毒性作用
Xiaopeng Meng,Yiran Yang,Jing Zhang et al.
Xiaopeng Meng et al.
Evidences supported many food additives (FAs) possess toxicity to human health due to chronic excessive exposure. Global hygienic standards strictly limit the dosage of each FA and mixture of the same functional FAs. However, the synergetic...
Effect of low-intensity pulsed ultrasound combined with Rhodiola rosea on proliferation and differentiation of osteoblasts [0.03%]
低强度脉冲超声联合红景天对骨形成的影响研究
Lanjun Zhang,Hang Yuan,Yongjun Tong et al.
Lanjun Zhang et al.
Osteoblasts (OB), as the mesenchymal progenitor cells differentiated from the inner and outer periosteum and the stroma in bone marrow, can specifically secrete a variety of bioactive substances, thereby regulating and influencing the proce...
PKD1 participates in the processing of aortic dissection via regulating vascular smooth muscle cell contraction and MAPK signaling [0.03%]
PKD1通过调节血管平滑肌细胞收缩和MAPK信号通路参与主动脉夹层的发生发展过程
Junbo Feng,Yuntao Hu,Peng Peng et al.
Junbo Feng et al.
Aortic Dissection (AD) is a cardiovascular emergency with high mortality, of which one feature is the phenotypic switch of vascular smooth muscle cells (VSMCs). Transient Receptor Potential Channel Interacting (PKD1) has been regarded as on...
GSDMD inhibitor protects chondrocyte from mechanical injury in human articular cartilage [0.03%]
GSDMD抑制剂保护人体关节软骨软骨细胞免受机械损伤
Chunye Tan,Linwei Li,Wenming Ma et al.
Chunye Tan et al.
Traumatic arthritis is caused by mechanical injury and results in the degeneration of articular cartilage, but it is unclear whether it is related to the pyroptosis of chondrocyte (CHs). Thus, this study was designed to investigate the role...
Erythropoietin relieves neuronal apoptosis in epilepsy rats via TGF-β/Smad signaling pathway [0.03%]
促红细胞生成素通过TGF-β/Smad信号通路缓解癫痫鼠神经元凋亡
Xiaoxiao Pan,Xiaoqian Gong,Lili Pan et al.
Xiaoxiao Pan et al.
This study aimed to investigate the influence of recombinant human erythropoietin (rHuEPO) on pentylenetetrazol (PTZ)-induced neuronal apoptosis in epilepsy rats, and to explore the signaling pathways related to the action. Healthy Sprague-...
Fasudil attenuates myocardial fibrosis in rats with diabetes mellitus via TGF-β1/Smad signaling pathway [0.03%]
法舒地尔通过TGF-β1/Smads信号途径减轻糖尿病大鼠心肌纤维化
Peng Zhang,Fei Wang,Jia Song et al.
Peng Zhang et al.
This research aimed to the study influence of fasudil (FAS) on myocardial fibrosis in rats with diabetes mellitus (DM) via the transforming growth factor-beta 1 (TGF-β1)/ small mothers against decapentaplegic (Smad) signaling pathway. A to...
Shaojun Wu,Jing Tang,Lin Wang
Shaojun Wu
This study was to investigate the effect and mechanism of Mus81 in severe PE. 20 cases of pregnant women with severe PE and 20 cases of healthy pregnant women were enrolled. Placental tissues were collected after delivery, and the expressio...
Peptostreptococcus anaerobius is a potential diagnostic biomarker of colorectal cancer [0.03%]
Peptostreptococcus anaerobius可作为结直肠癌诊断的生物标志物
Yuchao Zhang,Kaihu Fan,Linping Li et al.
Yuchao Zhang et al.
Accumulating evidences have shown that Peptostreptococcus anaerobius (P.a) is abundantly enriched in the fetus of colorectal cancer (CRC) patients. P.a is reported able to invade colorectal tissues. This study intends to uncover the clinica...
Identification of biomarkers associated with immune-propionate metabolism in nonalcoholic fatty liver disease [0.03%]
与非酒精性脂肪肝病免疫-丙酸代谢相关的生物标志物的鉴定
Shuye Qu,Hui Huang,Yan Diao et al.
Shuye Qu et al.
The mechanisms of the effect of propionate metabolism and immunity on nonalcoholic fatty liver disease (NAFLD) have not been adequately studied. Firstly, differentially expressed-propionate metabolism-related genes (DE-PMRGs) were selected ...