Effect of testosterone on the mRNA expression of Wnt-2 and dickkopf1 (DKK1), collagen deposition and oxidative stress in the cardiac tissue in male rats [0.03%]
睾酮对大鼠心脏组织Wnt-2、DKK1mRNA表达、胶原沉积和氧化应激的影响
Mahnaz Ghowsi,Sajjad Sisakhtnezhad,Youwei Wang
Mahnaz Ghowsi
Some studies suggest that misuse of androgenic-anabolic steroids may increase the risk of cardiovascular diseases in males. This study explored the effects of testosterone enanthate (TE) on the total antioxidant capacity (TAC) and malondial...
In vivo and in vitro action mechanism of treatment of glucocorticoid-induced osteoporosis by regulation of osteoprotegerin/receptor activator of nuclear factor-κB pathways by denshensu [0.03%]
丹参治疗糖皮质激素所致骨质疏松症的体内和体外作用机制及其对骨保护素/核因子κB受体活化剂途径的调节作用
Jianshi Li
Jianshi Li
The research aimed to discuss the action mechanism of the treatment of glucocorticoid-induced osteoporosis (GIOP) by denshensu. In the research, 60 rats were purchased and divided into a control group, model group, estradiol group, and dens...
Formation ability and drug resistance mechanism of Klebsiella pneumoniae biofilm and capsule for multidrug-resistant [0.03%]
耐多药肺炎克雷伯菌生物被膜和荚膜的形成能力及其耐药机制
Jiayu Liang,Shanshan Lin,Lanbo He
Jiayu Liang
This study was to explore the formation ability of biofilm and capsule and the drug resistance mechanism for multidrug-resistant Klebsiella pneumoniae. firstly, 55 strains of K. pneumoniae were screened out from the body fluid specimens of ...
The heat-labile enterotoxin B subunit bio-adjuvant linked to Newcastle disease virus recombinant hemagglutinin neuraminidase elicited a humoral immune response in animal model [0.03%]
热不稳定肠毒素B亚单位黏膜佐剂与新城疫病毒重组血凝素神经氨酸酶蛋白在动物模型中激发体液免疫反应
Mehregan Rahmani,Atena Mozafari,Mahyat Jafari et al.
Mehregan Rahmani et al.
Newcastle disease is a highly contagious viral infection primarily affecting poultry, leading to significant economic losses worldwide due to its high morbidity and mortality rates. Given the severity of the disease and its impact on the po...
Microsatellite-based diversity analysis and the development of core-set germplasm in Pakistani barley lines [0.03%]
基于微卫星的多样性分析及巴基斯坦大麦核心种质的建立
Murad Ali,Fiza Shaukat,Waqar Khan et al.
Murad Ali et al.
Illustrating the population structure and genetic diversity in selected germplasm resources (after three year multi locations trials) plays a key role which directly utilize the selection of lines in a population for accumulative trait bree...
Meta-analysis of the effect of FLT3 inhibitor maintenance therapy on survival and chronic graft-versus-host disease in allogeneic hematopoietic stem cell transplantation for malignant hematologic disease [0.03%]
FLT3抑制剂维持治疗对恶性血液系统疾病allo-HSCT后生存率和慢性移植物抗宿主病影响的meta分析研究
Xin Li,Lijun Li
Xin Li
This study aimed to investigate the effect of FLT3 inhibitor maintenance therapy on survival and chronic graft-versus-host diseases (cGVHD) in allogeneic hematopoietic stem cell transplantation (allo-HSCT) for malignant hematologic disease ...
Efficacy of timolol in the treatment of facial hemangioma and its effect on the proliferation and apoptosis of hemangioma stem cells [0.03%]
他莫西隆治疗血管瘤的疗效及其对血管瘤干细胞增殖和凋亡的影响研究
Hongjian Zhu,Hua Luo,Wenjuan Lai
Hongjian Zhu
To investigate the efficacy of timolol in the treatment of facial hemangioma and the effect on the proliferation and apoptosis of hemangioma stem cells, 60 cases of children with IHs admitted to our hospital between 2020 and 2021 were selec...
Deletion of the PPARδ gene exacerbates high-fat diet-induced nonalcoholic fatty liver disease in mice through the gut-liver axis [0.03%]
PPARδ基因缺失通过肠-肝轴加重高脂饮食诱导的小鼠非酒精性脂肪肝病
Ya-Tao Wang,Feng-Fan Wang,Hong Li et al.
Ya-Tao Wang et al.
Gut microbiota dysbiosis is an essential factor contributing to non-alcoholic fatty liver disease (NAFLD), in which the gut-liver axis plays a crucial role. Peroxisome proliferator-activated receptor δ (PPARδ) is considered a new directio...
Antiproliferative effect of Solanum nigrum L. water extract on breast can-cer cells: potential roles of apoptosis and oxidative stress [0.03%]
毛菍水提取物对乳腺癌细胞增殖抑制作用的初步研究及抗氧化和促凋亡作用机制探究
Haseeb A Khan,N Rajendra Prasad,Salman H Alrokayan et al.
Haseeb A Khan et al.
Breast cancer is the most progressive cancer among women worldwide. The currently available chemotherapeutic agents induce severe unacceptable adverse effects in breast cancer patients. In this context, natural medicinal herbs are gaining i...
Native and endemic Iranian Nepeta spp.: powerful antimicrobial agents [0.03%]
具有抗菌作用的本土及特有伊朗鼠尾草属植物（Nepeta）种类
Najmeh Hadi,Miloš Nikolić,Fatemeh Sefidkon et al.
Najmeh Hadi et al.
Pathogenic microorganisms are more or less successfully treated by synthetic chemical compounds, whose residues often cause serious health problems. Plant specialized metabolites with antimicrobial properties have for a long time been the f...