Impact of iodine supplementation and mtDNA mutations on papillary thyroid cancer in saudi women following a vegetarian diet [0.03%]
碘补充和线粒体DNA突变对沙特女性食素后患乳头状甲状腺癌的影响
Manal Abdulaziz Binobead,Wahidah H Al-Qahtani,Mashael Alhumaidi Alotaibi et al.
Manal Abdulaziz Binobead et al.
This study examined the influence of iodine supplementation and mitochondrial DNA (mtDNA) mutations in Saudi vegetarian women with papillary thyroid cancer (PTC). Blood and tissue samples from PTC-diagnosed women were analyzed for thyroid f...
miR-26 inhibits proliferation and promotes apoptosis of multiple myeloma cells by targeting BNIP3 [0.03%]
miR-26通过靶向BNIP3抑制多发性骨髓瘤细胞增殖并促进其凋亡
Meiyu Zhou,Tianxia Deng,Yonghong Tan et al.
Meiyu Zhou et al.
This study was carried out to investigate the molecular mechanism of microRNA-26 (miR-26) targeting BNIP3 to mediate proliferation and apoptosis of multiple myeloma (MM) cells. The expression of miR-26 and BNIP3 in MM and normal tissues was...
Mutational and expressional association of the PIK3CA gene with the risk of breast cancer in the Pakistani population [0.03%]
PIK3CA基因的突变和表达与巴基斯坦人群乳腺癌风险的相关性研究
Samina Asghar Abbasi,Rashida Khan,Mehvish Naseer Ahmed et al.
Samina Asghar Abbasi et al.
PI3K pathway is a very important pathway that is reported to be involved in breast cancer. Mutation of PI3K and p110 alpha-catalytic subunit of phosphatidylinositol 3-kinase (PIK3CA) is of high predictive and prognostic values in breast can...
Biochemical and gene expression studies reveal the potential of Aspergillus oryzae-fermented broken rice and brewers' rice water extracts as anti-photoageing agents [0.03%]
生化和基因表达研究揭示了发酵大米和酿酒大米水提取物作为抗光老化剂的潜力
Anisah Jamaluddin,Siti Muneerah Mohd Abd Rahman,Musaalbakri Abd Manan et al.
Anisah Jamaluddin et al.
In this study, UVA- and UVB-irradiated human fibroblasts were used to investigate the anti-photoaging efficacy of two aqueous extracts from Aspergillus oryzae-fermented broken rice (FBR) and brewers' rice (FBrR). As UVA and UVB can damage t...
Camk2a suppresses denervated muscle atrophy by maintaining the Ca2+ homeostasis in muscle cells [0.03%]
CaMKIIα通过维持肌肉细胞内的钙离子稳态抑制神经损伤引起的肌肉萎缩
Yanan Zhang,Mingjie Xia,Tianyu Zhao et al.
Yanan Zhang et al.
Denervated muscle atrophy is a severe neurological complication that significantly impacts patients' quality of life. Currently, there is a lack of effective treatment methods. This study aims to investigate the molecular mechanisms associa...
KRAS and MT-CO1 genes in colorectal cancer: a molecular investigation [0.03%]
结直肠癌中KRAS和MT-CO1基因的分子研究
Harmand A Hama,Bestoon S Hasan,Basak Barzngy et al.
Harmand A Hama et al.
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. The tumor suppressor gene MT-CO1, and Kristen Rat Sarcoma Virus (KRAS), an oncogene are primarily responsible for controlling cell apoptosis, cell cycle ...
Activin suppresses the expression of inflammatory genes and signaling proteins in human leukemia monocytic THP-1 cells [0.03%]
活化素通过抑制炎症基因和信号蛋白的表达来抑制人单核白血病THP-1细胞中的炎症反应
Sang Oh Yun,Young Il Kim,Hyung Joon Ahn et al.
Sang Oh Yun et al.
Activin regulates inflammation, cell proliferation, immune response, wound repair, and endocrine function. In this study, we investigated the effect of activin on inflammatory genes in THP-1 cells and the involvement of NF-κB, AKT, and mit...
Jun Ling Shan,Guang Yu Zhu,Li Hui Su et al.
Jun Ling Shan et al.
The skeletal system of the body is responsible for important functions in the human body. In addition to causing movement, this system also plays a role in the production of blood cells and fat storage. Bone marrow is a spongy or viscous ti...
Callus cell and explants regeneration, glucose, mineral, antioxidant and flavonoid content development using broccoli root tip and leaf cutting in vitro [0.03%]
基于根尖和叶段的布鲁姆科尔培养中愈伤组织细胞及外植体再生、糖类、矿质元素、抗氧化物质和黄酮类化合物的动态变化研究
Abm Sharif Hossain,Hassan A Alrudayni,Faouzi Haouala et al.
Abm Sharif Hossain et al.
The study was conducted to evaluate the root, shoot and leaf callus cell regeneration and its biochemical properties like antioxidant, carbohydrate, pigment and mineral content from broccoli root, shoot and leaf cutting in vitro. An in vitr...
Mutation analysis of the TERT gene in ovarian cancer patients of the Turkish population by next generation sequencing method [0.03%]
基于下一代测序技术分析土耳其人群卵巢癌患者的TERT基因突变
Betul Capar Gorali,Seda Gulec Yılmaz,Fatma Tuba Akdeniz et al.
Betul Capar Gorali et al.
Ovarian cancer (OC) ranks seventh among malignant tumors worldwide. As one of the most common gynecological malignancies, ovarian cancer has the second-highest mortality rate, after cervical and uterine cancer. Next-Generation Sequencing (N...