Identification of oxidative stress-related genes associated with immune cells in Aortic Valve Stenosis based on bioinformatics analysis [0.03%]
基于生物信息学分析鉴定氧化应激相关基因与主动脉瓣狭窄中免疫细胞的关系
Shanghai Li,Zhenjie Bai,Jinhai Quan et al.
Shanghai Li et al.
Aortic valve stenosis (AS) is the most common clinical valvular heart disease. Without effective pharmaceutical therapy at present, identifying effective therapeutic targets is critical. However, the pathological and molecular mechanisms of...
Injectable, pH-responsive hybrid hydrogels for the treatment of periodontitis [0.03%]
可注射的、对pH敏感的水凝胶杂合物在牙周病治疗中的应用
Rui Zhu,Wenhua Du,Xiaohui Mi
Rui Zhu
Anti-inflammatory hydrogels have demonstrated great potential in the treatment of periodontitis. However, intelligent removal of reactive oxygen species (ROS) remains significantly challenging. In this study, a novel pH-responsive anti-infl...
Knocking down of lncRNA SBF2-AS1 inhibits proliferation, invasion and induces apoptosis of colorectal cancer through regulating PTEN [0.03%]
敲低lncRNA SBF2-AS1通过调节PTEN抑制结直肠癌的增殖和侵袭并诱导其细胞凋亡
Yanyang Cai,Haibin Yan,Fang Wang et al.
Yanyang Cai et al.
To illustrate the potential function of lncRNA SBF2-AS1 in the progression of colorectal cancer (CRC) and the molecular mechanism. The relative level of SBF2-AS1 in CRC tissues and cell lines was determined by qRT-PCR. Its level in CRC pati...
Qing Hu,Peng Zhou,Yixuan Yan et al.
Qing Hu et al.
IgG4-related sialadenitis is a systemic autoimmune disease that can lead to fibro-inflammatory conditions. This study aims to investigate the immune microenvironment and potential signaling pathways associated with IgG4-related sialadenitis...
Quercetin relieves coronary atherosclerosis via regulating fibroblast growth factor 2 [0.03%]
黄酮通过调节成纤维细胞生长因子2缓解冠状动脉粥样硬化
Rui Shi,Zhaozheng Liu,Jinzhu Yin et al.
Rui Shi et al.
This study aims to investigate the role of quercetin in coronary atherosclerosis and explore its possible mechanisms. Hematoxylin-eosin (H&E), immunohistochemical (IHC), and aniline blue staining were used to analyze the pathological change...
Effects of simvastatin on immunoreaction and inflammation in rats with asthma by regulating NOTCH signaling pathway [0.03%]
西立伐他汀通过调节NOTCH信号通路对哮喘大鼠免疫反应及炎症的影响作用研究
Xiaomeng Zhang,Haixia Qiao,Min Li et al.
Xiaomeng Zhang et al.
To investigate the effect of simvastatin on the immunoreaction and inflammation in rats with asthma through the NOTCH signaling pathway, a total of 36 Sprague-Dawley (SD) rats were enrolled and randomly divided into the normal group (n=12),...
Clinicopathological and prognostic significance of elevated BTF3 expression in gastric cancer [0.03%]
胃癌中BTF3表达升高的临床病理和预后意义
Pu Zhang,Chaochen Wang,Haiqing Wang et al.
Pu Zhang et al.
The purpose of this paper was to explore the significance of basic transcription factor 3 (BTF3) in the process and clinicopathological parameters of gastric cancer (GC) patients. GC tissues were collected in our hospital to detect the mRNA...
Antioxidant, AChE inhibitory, and anticancer effects of Verbascum thapsus extract [0.03%]
鼠尾草提取物的抗氧化，乙酰胆碱酯酶抑制和抗癌作用
Na Zhang,Ayşe Baran,Ferzane Valioglu et al.
Na Zhang et al.
Verbascum thapsus (VT) is a medicinal plant that is used in folk medicine to treat a variety of ailments. For this study, the biological functions of VT methanol extract were determined in vitro. The plant's methanol extract was created thr...
GLP-1 receptor agonist liraglutide inhibits the proliferation and migration of thyroid cancer cells [0.03%]
GLP-1受体激动剂利拉鲁肽抑制甲状腺癌细胞的增殖和迁移
Xuelian Zhang,Liqiang Zhang,Bo Wang et al.
Xuelian Zhang et al.
This research was done to find out how liraglutide affected the growth and movement of two human thyroid cancer cell lines overexpressing GLP-1 receptor (migration of medullary thyroid cancer TT/GLP-1R and papillary thyroid carcinoma TCP-1/...
Long-non-coding RNA AK001058: A genetic biomarker in cisplatin sensitivity of non-small-cell lung carcinoma [0.03%]
长链非编码RNA AK001058：非小细胞肺癌顺铂敏感性的遗传生物标志物
Yongjun Deng,Huimin Li,Chao Liu et al.
Yongjun Deng et al.
Previous evidences have shown that lncRNA AK001058 serves as an oncogene. This study aims to elucidate the expression characteristic of AK001058 in NSCLC samples, and its potential influence on the malignant progression and cisplatin resist...