RGC-32 facilitates pancreatic cancer via activating Wnt/β-catenin signaling [0.03%]
RGC-32通过激活Wnt/β-catenin信号促进胰腺癌
Jinli He,Guihong Yang,Ronglai Cao et al.
Jinli He et al.
Longitudinal studies have indicated the facilitating effect of RGC-32 during diverse disease progression including pancreatic cancer, yet the systematic and detailed effect of RGC-32 during pancreatic cancer is largely unknowable. For this ...
Bone marrow mesenchymal stem cells-derived exosomal miR-185-5p plays a protective role in high-glucose stimulated human retinal microvascular endothelial cells in vitro by regulating CXCL8 [0.03%]
骨髓间充质干细胞来源的外泌体miR-185-5p通过调节CXCL8对高糖刺激的人视网膜微血管内皮细胞起保护作用的研究
Lin Zhou,Weixia Wang
Lin Zhou
In this study, we intended to probe the impacts and mechanism of bone marrow mesenchymal stem cells (BM-MSCs)-derived exosomal miR-185-5p on angiogenesis and inflammatory response in diabetic retinopathy (DR). Based on the GEO database, we ...
The relationship between the expression of lncRNA MALAT1 and clinical features and prognosis in bladder cancer: A meta-analysis [0.03%]
lncRNA MALAT1的表达与膀胱癌的临床特征和预后的关系：一项荟萃分析
Yi Su,Hong Chen,Lifeng Yao et al.
Yi Su et al.
The objective of this meta-analysis is to evaluate the association between LncRNA MALAT1 and the clinicopathological characteristics and prognosis in patients with bladder cancer. Related studies were searched from Pubmed, Embase, Cochrane ...
KIAA0101 promotes cisplatin resistance through regulating cell apoptosis in lung cancer cells [0.03%]
KIAA0101通过调节肺癌细胞的凋亡来促进顺铂耐药性
Cian Zhang,Yongying Liu,Jing Zhao et al.
Cian Zhang et al.
Lung cancer is one of the most server mortality in the world and remains a huge threat to human health. Recently, cisplatin-based chemotherapy represented a common therapeutic strategy, however, cisplatin resistance greatly limits the thera...
Association of IL-8 levels in serum and bronchoalveolar lavage fluid with sputum emboli in children with lobar pneumonia [0.03%]
血清和支气管肺泡灌洗液中IL-8水平与大叶性肺炎儿童痰栓的关联性研究
Qingqing Chen,Na Lv,Xue Wang et al.
Qingqing Chen et al.
To provide a clinical reference for the management of lobar pneumonia (LP) by analyzing the association of interleukin-8 (IL-8) with the disease. A retrospective analysis was performed on 69 LP children (observation group, OG) and 60 health...
Evaluation of the diagnostic performance of Alpha-1-Antitrypsin in early detection of hepatocellular carcinoma [0.03%]
α1-抗糜蛋白酶在肝细胞癌早期检测中诊断性能的评估
Mohammed Q Sultan,Bassem Charfeddine,Aws Rassul Hussain Al-Salih
Mohammed Q Sultan
Hepatocellular carcinoma (HCC) constitutes one of the most frequent cancer types and accounting the vast majority of tumour-related fatalities worldwide. HCC is remain related to a bad prognosis in patients with an advanced disease stage. T...
TRPM8 knockdown relieved inflammatory response and cell apoptosis in pneumonia model induced by Streptococcus pneumoniae in vitro [0.03%]
TRPM8敲减在体外链球菌肺炎模型中缓解了炎症反应和细胞凋亡
Kui Sheng,Linli Sang,Hui Ge
Kui Sheng
Streptococcus pneumoniae infection remains a leading cause of pneumonia-related deaths. Transient receptor potential melastatin 8 (TRPM8) exerts crucial roles in lung diseases. We first dissected the role of TRPM8 in pneumococcal pneumonia ...
Low vitamin D level increases women's breast cancer risks, Sulaimaniyah, Iraq: A case-control study [0.03%]
低维生素D水平增加伊拉克女性患乳腺癌的风险：一项病例对照研究
Mardin Othman Abdulqadir,Niaz Mustafa Kamal,Heshu Sulaiman Rahman
Mardin Othman Abdulqadir
Vitamin D (Vit D) is essential in maintaining calcium homeostasis and other body processes. It has been widely studied how Vit D affects cell cycle pathways and how it affects the development and prevention of breast cancer (BC). This study...
Biological functions of miRNA-203b-3p/ZNF324 in laryngeal carcinoma [0.03%]
miRNA-203b-3p/ZNF324在喉癌中的生物功能研究
Liping Wang,Xianyang Luo
Liping Wang
The present study aimed to elucidate the role of MicroRNA-203b-3p (miRNA-203b-3p) in protecting the deterioration of laryngeal carcinoma through targeting ZNF324. Relative levels of miRNA-203b-3p and ZNF324 in laryngeal carcinoma tissues wi...
Pyrotinib shows a potent antitumor effect on HER2-positive esophageal cancer cells by promoting HER2 proteasomal degradation [0.03%]
通过促进HER2蛋白酶体降解吡咯替尼对HER2阳性食道癌细胞表现出强抗肿瘤作用
Fei Zhao,Tienian Zhu,Ruijing Zhao et al.
Fei Zhao et al.
Pan-HER TKIs (pyrotinib, lapatinib) are potent HER2 inhibitors, however, their anti-tumor efficacy on esophageal cancer remains to be elucidated. Using two HER2-positive esophageal cancer cell lines, we observed that both pyrotinib and lapa...