METTL3-modified lncRNA-MALAT1 regulates the molecular axis of miR-124-3p/CDK4 involved in Ewing's sarcoma [0.03%]
METTL3修饰的lncRNA-MALAT1通过调节Ewing肉瘤中miR-124-3p/CDK4分子轴发挥作用
Fangzhou He,Tingting Ren,Xiaodong Tang
Fangzhou He
N6-methyladenosine (m6A) modifications are considered key mechanisms in cancer. As an m6A-modified lncRNA, MALAT1 is associated with tumor progression. In this study, the MALAT1/miR-124-3p/CDK4 axis was studied to discover METTL3's effects ...
Changes in Lipid biomarker related to trauma severity in intertrochanteric fracture patients [0.03%]
股骨转子间骨折患者血脂生物标志物与创伤严重程度的相关性变化
Yang Chen,Gang Ye,Daniel Edwards Porter et al.
Yang Chen et al.
This study aimed to identify whether there are elevations or declines in specific plasma lipids in intertrochanteric fracture (ITF) patients which might serve as potential biomarkers for assessing the severity of trauma, or therapeutic targ...
Identification and functional analysis of novel biomarkers in adenoid cystic carcinoma [0.03%]
腺样囊性癌的新型生物标志物鉴定及功能分析
Jiang Su,Wei Zhou,Huajie Yuan et al.
Jiang Su et al.
To explore the key genes associated with the development and progression of adenoid cystic carcinoma (ACC), with the aim of exploring novel biomarkers that can better diagnose ACC, and thus better improve patient prognosis. The GSE59701 and...
A study on the mechanism of action of YiQiYangYindecotion for the treatment of diabetes based on network pharmacology [0.03%]
基于网络药理学的益气养阴方治疗糖尿病作用机制研究
Ru Liu,Jing Xu,Qian Lu
Ru Liu
To study the mechanism of action of YiQiYangYin decoction on diabetes mellitus by a network pharmacology method. The chemical components and targets of all the drugs in the YiQiYangYin decoction were obtained through the Traditional Chinese...
FOXN4 affects myocardial ischemia-reperfusion injury through HIF-1α/MMP2-mediated ferroptosis of cardiomyocytes [0.03%]
FOXN4通过HIF-1α/MMP2介导的心肌细胞铁死亡影响心肌缺血再灌注损伤
Jiyang Wang,Min Deng,Jiaona Yang et al.
Jiyang Wang et al.
Myocardial ischemia-reperfusion injury (MIRI) is an important factor leading to myocardial injury and necrosis, and can induce ischemic heart disease. Forkhead box protein N4 (FOXN4) belongs to the gene family of Fork head domain (Fox) tran...
The Relationship among the Performance and the ACE I/D and ACTN3 R577X Polymorphisms and some Anthropometric Factors in Arm Wrestlers [0.03%]
ACE I/D和ACTN3 R577X多态性以及一些体质因素与力量型运动员运动成绩的关系研究
Raif Zileli,Onur Eroğlu,Muhammed Ali Nalbant et al.
Raif Zileli et al.
Sport genetics has become increasingly important in recent years. The concept of performance includes genetic and anthropometric factors. These factors have not been adequately examined when the current literature is examined. One of the ai...
Abdulaziz Alqahtani,Alzhraa Ali Mohamed,Irfan Ahmad et al.
Abdulaziz Alqahtani et al.
Multidrug-resistant (MDR) bacteria are one of the major public health threats facing humanity. Infections with MDR strains are difficult or impossible to treat with standard antibiotics leading to severe illnesses and even deaths. The sprea...
HDAC inhibitor SB939 potentiates TRAIL-induced apoptosis in colorectal cancer cells [0.03%]
组蛋白脱乙酰酶抑制剂SB939增强TRAIL诱导的结直肠癌细胞凋亡作用
Min Woo Shin,Seung Young Seo,Se Lim Kim et al.
Min Woo Shin et al.
Colorectal cancer (CRC) displays noticeable resistance to chemotherapeutic drugs or innovative tumor cell apoptosis-inducing agents such as tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Thus, sensitizers are needed to enh...
Molecular Mechanism of Bai-Bo Formula for Treatment of Vitiligo Based on Network Pharmacology and Molecular Docking [0.03%]
基于网络药理学和分子对接的白驳汤治疗白癜的分子机制研究
Kaibo Zhang,Bin Zhang,Yeqiang Song
Kaibo Zhang
Using network pharmacology and molecular docking, this study aims to evaluate the pharmacological mechanism of Bai-Bo Formula in the prevention and treatment of vitiligo. The chemical composition collection and anticipated targets for Bai-B...
Molecular detection of different virulence factors genes harbor pslA, pelA, exoS, toxA and algD among biofilm-forming clinical isolates of Pseudomonas aeruginosa [0.03%]
分子检测生物被膜形成临床分离铜绿假单胞菌中不同毒力因素基因pslA、pelA、exoS、toxA和algD的携带情况
Rehab E Farhan,Samar M Solyman,Amro M Hanora et al.
Rehab E Farhan et al.
Pseudomonas aeruginosa (P. aeruginosa) is considered as the foremost cause of hospital-acquired infections due to its innate and plasmid-mediated resistance to multiple antibiotics making it a multi-drug resistant (MDR) pathogen. This study...