Effect of Xamoterol administration into the shell nucleus accumbens of rats on anxiety-like behavior and emotional memory [0.03%]
西马泽特啉在大鼠伏隔核内给药对焦虑及情绪记忆的影响
Kimia Najafi,Yasaman Vakiloroaya,Batool Ghorbani Yekta et al.
Kimia Najafi et al.
Beta-adrenergic receptors are involved in anxiety disorders and help regulate anxiety-like behaviors. The nucleus accumbens (NAc), an important brain structure for emotional regulation and learning, plays a crucial role in anxiety. However,...
A novel peptide cocktail containing B and T cell epitopes confers robust protection against Staphylococcus aureus bacteremia in a murine model [0.03%]
一种含有B细胞表位和T细胞表位的新型肽混合物可使小鼠在金黄色葡萄球菌菌血症模型中得到良好保护
Shymaa Kamal,Samar Solyman,Amro Hanora
Shymaa Kamal
Previous Staphylococcus aureus vaccines have been unsuccessful, but it seems that including T cell immunity in the vaccine is essential for its success. This study used Metal ABC transporter substrate-binding protein (MABC), Nickel ABC tran...
In-silico evaluation of the efficacy of essential oils from Artemisia absinthium, Artemisia herba-alba, and Artemisia annua against SARS-CoV-2 [0.03%]
牛膝菊、艾草和黄花蒿精油对SARS-CoV-2的抑制活性预测研究
Nawel Bouzerea,Nesrine Feknous,Sandra Feknous et al.
Nawel Bouzerea et al.
Since the outbreak of COVID-19 in China in December 2019, the pandemic has spread to almost every country in the world, resulting in more than half a billion sick patients and more than seven million victims. The objective of our present st...
Folic acid-decorated tamoxifen-loaded covalent organic framework induces apoptosis in MCF-7 breast cancer cells via BAX/Caspase-8 upregulation [0.03%]
叶酸修饰的载他莫昔芬共价有机框架通过上调BAX/Caspase-8诱导MCF-7乳腺癌细胞凋亡
Akash Chandran,Sudhina S,Radhika A et al.
Akash Chandran et al.
The side effects and non-specific targeting of healthy organs associated with conventional cancer therapies necessitate the design and fabrication of novel nanomaterial-based drug delivery systems. In this study, we successfully fabricated ...
Optimized enzymatic cell lysis protocols for single-cell genomic analysis [0.03%]
单细胞基因组分析的优化酶裂解细胞方案
Houssam Raad,Hamid Bou Saab,Ahmad Al Saabi et al.
Houssam Raad et al.
Optimizing cell lysis is essential for reliable single-cell genomic analysis. This study sought to refine enzymatic lysis conditions to minimize incubation time while maintaining DNA integrity. Microdissected human leukocytes were digested ...
Screening for MSX1 and PAX9 gene variants among hypodontia patients in the Jordanian population [0.03%]
在约旦人群中的牙数不足患者中筛查MSX1和PAX9基因变异类型
Areej Quran,Ahmed Maslat,Saied Jaradat et al.
Areej Quran et al.
This study aimed to sequence the PAX9 and MSX1 genes in a group of Jordanian patients diagnosed with non-syndromic hypodontia. The study also examined whether the identified genetic variants in these key odontogenic genes could be used to a...
Clinicopathological Characteristics of PRRX1 and PRRX2 Genes Expressions in Colorectal Cancer Patients [0.03%]
PRRX1和PRRX2基因在结直肠癌中的临床病理特征分析
Samira Zaman Nezhad,Zahra Mozooni,Amirhossein Eskandari et al.
Samira Zaman Nezhad et al.
Colorectal cancer (CRC) ranks as the third leading cause of cancer-related deaths globally. It results from polyp growth or ulcers formation in the colon or intestine lining. Genetic, environmental factors, unhealthy eating habits, and life...
Advances in algal biofuel production through catalysts and nanocatalysts: an integrated chemical, biochemical, and physical analysis [0.03%]
集成化学、生化和物理分析的催化剂和纳米催化剂在藻类燃料生产的进展研究
Anis Ahmad Chaudhary
Anis Ahmad Chaudhary
Biofuel has emerged as one of the most promising alternatives to petroleum-derived fuels, particularly in the current context of rapidly depleting fossil fuel reserves. The combustion of fossil-based fuels poses serious risks to both the en...
Modulatory effects of Mentha longifolia and Mentha spicata essential oils on Candida albicans biofilm formation [0.03%]
薄荷和绿薄荷精油对白色念珠菌生物膜形成的作用效果研究
Ayshah Alrashidi,Badria Abd El-Rahman Husin Husin,Meshari Alazmi et al.
Ayshah Alrashidi et al.
Mentha longifolia (horsemint) and Mentha spicata (spearmint) are economically valuable aromatic plants widely utilized in food, cosmetic, and pharmaceutical industries due to their rich reservoir of bioactive compounds. This study investiga...
Piezo1-mediated cellular apoptosis in breast cancer cells triggered by ultrasound and microbubbles [0.03%]
超声和微泡触发的乳腺癌细胞凋亡中的Piezo1介导作用
Nina Qu,Menglu Bi,Qingkai Meng et al.
Nina Qu et al.
Piezo1 ion channels play a crucial role in apoptosis regulation in human breast cancer cells (MCF-7), and this study evaluates the effects of Piezo1 agonist (Yoda1), inhibitor (GsMTx4), and ultrasound microbubble (USMB) treatment on cellula...