Dupilumab as maintenance therapy in steroid-dependent eosinophilic enteritis: a multidisciplinary approach [0.03%]
dupilumab用作依赖激素的嗜酸细胞性肠炎维持治疗的多学科方法研究
Íñigo Roa Esparza,Irene Arteagoitia Casero,Mario Salvador Argueta Valdez et al.
Íñigo Roa Esparza et al.
Eosinophilic enteritis is a rare immune-mediated disorder for which systemic corticosteroids remain the mainstay of treatment during acute flares, although no standardized maintenance therapy exists and some patients develop recurrent disea...
Sweet legacy, bitter outcomes: sugar, sweeteners, and the microbial origins of a modern syndrome. An evidence-based narrative review [0.03%]
甜蜜的遗产，苦涩的结果：糖、甜味剂和现代综合征的微生物起源。基于证据的故事性回顾
Daniel Ceballos,María Caba,Cristian Almeida et al.
Daniel Ceballos et al.
The consumption of added sugars and artificial sweeteners has risen exponentially in recent decades, driven by industrial availability, food processing, and Western dietary patterns. This narrative review, adopting a critical and multidisci...
Ferroptosis in intestinal ischemia-reperfusion injury: a systematic review and meta-analysis [0.03%]
肠道缺血再灌注损伤中铁死亡作用的系统评价和meta分析
Zicen Zhao,Yuxuan Wu,Yufang Leng et al.
Zicen Zhao et al.
Purpose: This meta-analysis evaluated changes in ferroptosis-related factors during intestinal ischemia-reperfusion injury by integrating data from animal experiments. ...
Routine X-ray contrast study after peroral endoscopic myotomy does not improve patient outcomes [0.03%]
经口内镜肌切开术后常规进行X线造影检查并不能改善患者的预后
Marek Vojtko,Martin Ďuriček,Zuzana Trabalková et al.
Marek Vojtko et al.
Study Background and Aim: Peroral endoscopic myotomy (POEM) is a primary treatment for achalasia. Traditionally, oral feeding is initiated after an X-ray contrast study excludes the post-procedure leak. However, since major adverse events (...
Collagen expression downregulation and intestinal barrier impairment are associated with severe clinical phenotypes in very early-onset inflammatory bowel disease [0.03%]
胶原表达下调和肠屏障功能障碍与Very Early Onset炎症性肠病的严重临床表型相关
Hefang Wu,Hongwei Guo,Anding Zhang et al.
Hefang Wu et al.
Background: The global incidence of pediatric inflammatory bowel disease (IBD) is increasing steadily. Children with IBD under 6 years present unique clinical characteristics. ...
Andrea Boscà Robledo,Eva María Montalvá Orón,Rafael López-Andújar
Andrea Boscà Robledo
The indication for liver transplantation in liver metastases from neuroendocrine tumors is to improve overall survival and disease-free survival in these patients. The selection criteria for candidates are strict, and although few patients ...
Stent insertion for malignant esophageal strictures: endoscopy with fluoroscopy or endoscopy alone [0.03%]
恶性食管狭窄置入支架：内镜联合透视与单纯内镜的对比研究
Jesús García-Cano,Francisco Domper,María Rodríguez
Jesús García-Cano
Dysphagia is a debilitating consequence for patients with esophageal cancer. Recanalization of the obstruction with esophageal stents is one of the palliative measures that can most improve the quality of life in these patients. Among patie...
Evaluating the efficacy of PD-1 or PD-L1 inhibitors in gastric cancer patients [0.03%]
评价PD-1或PD-L1抑制剂在胃癌患者中的疗效
Zhuo Han,Haicheng Yang,Tao Wu et al.
Zhuo Han et al.
Objective: This study aims to assess the therapeutic advantages of PD-1 and PD-L1 inhibitors for gastric cancer (GC) patients and determine which of the two agents confers greater benefits. ...
Severe adverse events associated with thiopurine therapy in inflammatory bowel disease: A retrospective cohort study from a tertiary centerInflammatory Bowel Disease: A Retrospective Cohort Study from a Tertiary Center [0.03%]
硫嘌呤治疗炎症性肠病严重不良事件的回顾队列研究
Luís Enrique Frisancho,Eduard Brunet-Mas,Belén García Sagué et al.
Luís Enrique Frisancho et al.
Background and aim of the study: Thiopurines are cornerstone immunosuppressants for maintenance therapy in inflammatory bowel disease, but their use is limited by potentially serious adverse events. The aim of this study ...
Ductal plate malformation revisited ‒ Hepatobiliary manifestations of polycystic kidney and liver disease [0.03%]
再访肝板畸形：多囊性肾脏和肝脏疾病的胆汁淤积表现
Manuel Romero-Martínez,Alberto Gómez Gómez,Marcos Sánchez Martínez et al.
Manuel Romero-Martínez et al.
Polycystic kidney diseases are linked to a myriad of hepatobiliary diseases. Patients with such diseases have a higher risk of admission. Clinical manifestations and complementary testing differ from healthy controls leading to suboptimal c...