Improvements in pain, medication use and quality of life in onabotulinumtoxinA-resistant chronic migraine patients following erenumab treatment - real world outcomes [0.03%]
对慢性偏头痛患者在抗CGRP抗体治疗后的疼痛、用药和生活质量的改善：真实世界结果
J Talbot,R Stuckey,L Crawford et al.
J Talbot et al.
Background: The CGRP antagonists offer a novel therapeutic approach in migraine. Their utility in patients with severe forms of chronic migraine is a subject of particular interest. We present outcomes of 9 months of eren...
Immunogenicity of biologic therapies for migraine: a review of current evidence [0.03%]
偏头痛的生物疗法免疫原性的当前证据综述
Joshua M Cohen,Xiaoping Ning,Yoel Kessler et al.
Joshua M Cohen et al.
Background: Monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway have been shown to be effective in migraine prevention. Eptinezumab, erenumab, fremanezumab, and galcanezumb have shown...
Differential alteration of fMRI signal variability in the ascending trigeminal somatosensory and pain modulatory pathways in migraine [0.03%]
头痛型偏头痛上升三叉神经感觉和疼痛调节通路的功能磁共振信号变异性的变化不同
Manyoel Lim,Hassan Jassar,Dajung J Kim et al.
Manyoel Lim et al.
Background: The moment-to-moment variability of resting-state brain activity has been suggested to play an active role in chronic pain. Here, we investigated the regional blood-oxygen-level-dependent signal variability (B...
Treatment benefit among migraine patients taking fremanezumab: results from a post hoc responder analysis of two placebo-controlled trials [0.03%]
法布纳珠单抗治疗偏头痛患者的疗效：一项针对2项安慰剂对照试验的事后分析结果
Stephen D Silberstein,Joshua M Cohen,Ronghua Yang et al.
Stephen D Silberstein et al.
Background: Monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway, including the fully humanized monoclonal antibody (IgG2Δa) fremanezumab, have demonstrated safety and efficacy for migraine ...
Randomized Controlled Trial
The journal of headache and pain. 2021 Jan 7;22(1):2. DOI:10.1186/s10194-020-01212-4 2021
Association between response to triptans and response to erenumab: real-life data [0.03%]
偏头痛患者对曲坦类药物反应情况与对erenumab（ERN）反应情况的相关性分析：真实世界数据
Ilaria Frattale,Valeria Caponnetto,Alfonsina Casalena et al.
Ilaria Frattale et al.
Background: Triptans and erenumab are both migraine-specific agents acting on the calcitonin gene-related peptide pathway. Therefore, response to triptans might be associated with response to erenumab. ...
Neuromodulation techniques for acute and preventive migraine treatment: a systematic review and meta-analysis of randomized controlled trials [0.03%]
急性与预防性偏头痛治疗的神经调控技术：随机对照试验的系统评价和.meta.分析
Xavier Moisset,Bruno Pereira,Daniel Ciampi de Andrade et al.
Xavier Moisset et al.
Background: Several neuromodulation methods exists for migraine treatment. The aim of the present study was to perform a systematic review and meta-analysis of randomized controlled trials (RCTs) focusing on migraine trea...
Concurrent brain structural and functional alterations in patients with migraine without aura: an fMRI study [0.03%]
无先兆偏头痛患者的脑结构和功能的同步改变：一项fMRI研究
Zhengjie Li,Jun Zhou,Lei Lan et al.
Zhengjie Li et al.
Objectives: To explore the possible concurrent brain functional and structural alterations in patients with migraine without aura (MwoA) patients compared to healthy subjects (HS). ...
Correction to: The knockdown of Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion [0.03%]
Correction to: 敲低神经肽FF受体2抑制辣椒素诱导的小鼠三叉神经节中CGRP上调
Ya-Tin Lin,Zachary Yu,Sze-Chi Tsai et al.
Ya-Tin Lin et al.
An amendment to this paper has been published and can be accessed via the original article.
Published Erratum
The journal of headache and pain. 2020 Dec 7;21(1):140. DOI:10.1186/s10194-020-01209-z 2020
Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal [0.03%]
metab型谷氨酸受体5通过PKC/NR2B信号调节慢性偏头痛大鼠模型的突触可塑性
Yingying Niu,Xiaoxu Zeng,Lilin Zhao et al.
Yingying Niu et al.
Background: The mechanism of chronic migraine (CM) is complex, central sensitization is considered as one of the pathological mechanism. Synaptic plasticity is the basis of central sensitization. Metabotropic glutamate re...
The role of deficient pain modulatory systems in the development of persistent post-traumatic headaches following mild traumatic brain injury: an exploratory longitudinal study [0.03%]
疼痛调节系统缺陷在轻度脑外伤后慢性创伤性头痛发病中的作用：一项探索性的纵向研究
Kelly M Naugle,Christopher Carey,Eric Evans et al.
Kelly M Naugle et al.
Background: Post-traumatic headache (PTH) is one of the most common and long-lasting symptoms following mild traumatic brain injury (TBI). However, the pathological mechanisms underlying the development of persistent PTH ...