S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis [0.03%]
S100A11通过H3K27ac-TFEB-线粒体自噬轴调节神经病理性疼痛小胶质细胞炎症反应
Heqing Zheng,Sheng Tian,Lanxiang Wu et al.
Heqing Zheng et al.
Neuropathic pain (NP) is tightly linked to spinal microglial overactivation, sustained neuroinflammation; however, the key molecular regulators and epigenetic circuitry driving microglial functional dyshomeostasis remain incompletely define...
Anti-CGRP receptor antibodies do not modulate trigeminal pain processing: indication for distinct mechanisms of CGRP pathway blockade [0.03%]
抗CGRP受体抗体不会调节三叉神经痛处理：表明CGRP通路阻断的机制不同
Kuan-Po Peng,Hauke Basedau,Karl Messlinger et al.
Kuan-Po Peng et al.
Background: Monoclonal antibodies (mAbs) targeting calcitonin gene-related peptides (CGRP) are established therapies for migraine. There are currently four CGRP-mAbs available on the market: one targets the CGRP receptor,...
Prescriber adherence to treatment guidelines for monoclonal antibodies against Calcitonin Gene-Related Peptide in migraine prophylaxis - a register-based cohort study [0.03%]
单克隆抗体反钙调神经磷酸肽在偏头痛预防中的治疗指南依从性——一项基于登记处的队列研究
Sofia Nordenmalm,Rickard E Malmström,Sara Freyland et al.
Sofia Nordenmalm et al.
Safety and efficacy of occipital nerve stimulation as treatment of chronic cluster headache: an investigator-initiated, double-blind, randomized, placebo-controlled study [0.03%]
枕神经刺激治疗慢性丛集性头痛的疗效和安全性：一项研究者发起的、双盲随机对照试验
Ida Stisen Fogh-Andersen,Jens Christian Hedemann Sørensen,Anja Sofie Petersen et al.
Ida Stisen Fogh-Andersen et al.
Background: Occipital nerve stimulation has shown promising results in attack prevention in patients with chronic cluster headache, but evidence from controlled trials is scarce. Conventional (tonic) occipital nerve stimu...
Genetic subtraction reveals divergent pathways and targets in anxiety-related and anxiety-independent TMD [0.03%]
遗传学减法发现焦虑相关和非焦虑依赖性TMD的分歧途径和靶点
Yu Cao,Xin Yang,Peter Svensson et al.
Yu Cao et al.
Iron concentration in the ventral pallidum of chronic migraine with medication-overuse headache [0.03%]
药物过度使用性慢性偏头痛患者腹侧苍白球铁含量测定
Xiaopei Xu,Jiahui He,Mengting Zhou et al.
Xiaopei Xu et al.
Background: Chronic migraine (CM) imposes a significant disease burden and frequently co-occurs with medication-overuse headache (MOH). MOH is a secondary headache disorder occurring especially in individuals with primary...
Unveiling state-specific neural dynamics in migraine with and without depressive symptom: a hidden Markov model and interpretable machine learning approach [0.03%]
基于隐藏马尔可夫模型和可解释机器学习的偏头痛及其伴或不伴有抑郁症状的个体化脑网络动态研究
Zhiyang Zhang,Chaorong Xie,Linglin Dong et al.
Zhiyang Zhang et al.
Timothy J Steiner,Latifa Adarmouch,Amalie Berring-Uldum et al.
Timothy J Steiner et al.
Epidemiology of primary headache and lifestyle factors among children and adolescents: a regional school-based study in China [0.03%]
中国在校儿童和青少年原发性头痛的流行病学及生活方式因素：一项区域校内研究
Guangshuang Lu,Xiaojing Li,Chaofei Bi et al.
Guangshuang Lu et al.
Altered dorsal anterior insula functional connectivity underlying abnormal interoceptive accuracy awareness in migraine without aura [0.03%]
无先兆偏头痛患者内感受准确性异常的相关背外侧前绝缘皮层功能连接的改变
Ruihua Liu,Yuanxiang Li,Ruidi Wang et al.
Ruihua Liu et al.
Background: Abnormal interoception is increasingly recognized as a key feature of migraine. The dorsal anterior insula (dAI) is hypothesized to play a central role in interoceptive processing, yet the neural mechanisms un...