The emerging role of the meningeal lymphatic and glymphatic systems in migraine pathophysiology: a systematic review [0.03%]
脑膜淋巴系统和胶质淋巴系统在偏头痛发病机制中的作用：系统性综述
Kimia Bagheri,Hadi Sahrai,Negin Safari Dehnavi et al.
Kimia Bagheri et al.
Background/objective: Migraine is a common, debilitating neurological disorder of unclear pathophysiology. Recent evidence has implicated impaired meningeal lymphatic function and its interaction with the glymphatic syste...
Long-term safety and continued clinical benefit of erenumab 70 mg in Asian patients with chronic migraine: an open-label extension of the phase 3 DRAGON study [0.03%]
亚洲慢性偏头痛患者长期使用erenumab 70毫克治疗的安全性与持续临床获益：开放延伸研究DRAGON三期临床试验
Shengyuan Yu,Byung-Kun Kim,Hebo Wang et al.
Shengyuan Yu et al.
Background: Erenumab is a fully human monoclonal antibody targeting the calcitonin gene-related peptide receptor. Several double-blind studies have demonstrated the clinical benefits of erenumab in migraine prevention. Ho...
Clinical characteristics of perimenopausal migraine and its correlation to hormonal levels [0.03%]
围绝经期偏头痛的临床特征及其与激素水平的相关性
Lobna Talaat El-Ghoneimy,Nervana M Elfayoumy,Hanan Helmy et al.
Lobna Talaat El-Ghoneimy et al.
Background: Studies about perimenopausal migraine are limited. In this study, we aimed to explore the characteristics of perimenopausal migraine and to compare perimenopausal women with and without migraine in terms of th...
Efficacy and safety of eptinezumab in adults with chronic migraine and medication-overuse headache who also received patient education: 24-week results of the randomized RESOLUTION trial [0.03%]
成人慢性偏头痛和药物过量性头痛患者的依替佐木单抗疗效和安全性：附患者教育的随机II期RESOLUTION试验24周结果
Henrik W Schytz,Rigmor H Jensen,Christofer Lundqvist et al.
Henrik W Schytz et al.
Background: The phase 4 RESOLUTION trial showed that the first 12 weeks of treatment with eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody, reduced migraine frequency, severity, and disease burden,...
CGRP-provoked headache is associated with a neuroimmune signature in idiopathic intracranial hypertension [0.03%]
促CGRP头痛与特发性颅内高压的神经免疫特征相关
Andreas Yiangou,Thien Phu Do,Olivia Grech et al.
Andreas Yiangou et al.
Background: Idiopathic intracranial hypertension (IIH) is characterised by raised intracranial pressure and disabling headaches, yet its underlying mechanisms remain poorly defined. Calcitonin gene-related peptide (CGRP) ...
Early life stress induces brain-wide electrical network predisposition to migraine [0.03%]
早期压力通过诱导广泛的脑电网络倾向性而成为偏头痛的发病因素
Micah Johnson,Maureen Eberle,Ian Hultman et al.
Micah Johnson et al.
Background: Migraine is a disorder of severe, recurrent headaches and debilitating sensory, cognitive and affective symptoms, often triggered by stress. Early life stress in childhood has been shown to increase the likeli...
CD4+T cells mediate systemic and local immune changes and pain symptoms in the rat model of temporomandibular disorders related pain [0.03%]
CD4⁺T细胞介导的大鼠颞下颌紊乱相关疼痛模型中的全身及局部免疫变化和痛觉症状
Jianquan He,Yuzhuo Hei,Lin Li et al.
Jianquan He et al.
Background and purpose: Immune cells involved in pain has received increasing attention, but the available literature on the role of T cells in temporomandibular disorders (TMD) related pain is limited. Our previous study...
Consistency of response to rimegepant for the acute treatment of migraine among real-world users - findings from the prospective observational CONFIDENCE study [0.03%]
REALITY研究：rimegepant治疗偏头痛急性发作疗效的持久性：CONFIDENCE研究结果
Richard B Lipton,Lucy Abraham,Alexandre Urani et al.
Richard B Lipton et al.
Background: Real-world data on the effectiveness of rimegepant for the acute treatment of migraine is limited, particularly regarding consistency of response over multiple attacks. ...
Oscillatory edge connectivity in pain-related regions supports machine learning identification of migraine [0.03%]
与疼痛相关区域的振荡边缘连接性支持机器学习识别偏头痛
Fu-Jung Hsiao,Kuan-Lin Lai,Wei-Ta Chen et al.
Fu-Jung Hsiao et al.
Background: Objective and interpretable brain signatures for migraine diagnosis and phenotyping remain limited. Edge-centric connectivity treats interregional connections as primary analytical units and captures higher-or...
Blood-brain barrier integrity and brain entropy in reversible cerebral vasoconstriction syndrome [0.03%]
可逆性脑血管收缩综合征患者血脑屏障完整性和脑熵的研究
Chia-Hung Wu,Tun-Wei Hsu,Yu-Hsiang Ling et al.
Chia-Hung Wu et al.
Background: Elucidating functional brain dynamics under different blood-brain barrier (BBB) permeabilities may resolve the enigmatic pathophysiology of reversible cerebral vasoconstriction (RCVS); however, relevant invest...