Early onset of effect following galcanezumab treatment in patients with previous preventive medication failures [0.03%]
对于之前预防性治疗失败的患者，加尼珠单抗治疗早期起效
Todd J Schwedt,Dulanji K Kuruppu,Yan Dong et al.
Todd J Schwedt et al.
Background: Galcanezumab is a monoclonal antibody (mAb) that binds calcitonin gene-related peptide (CGRP) and is indicated for the preventive treatment of migraine. Galcanezumab demonstrated early onset of effect in patie...
Yu-Hsiang Ling,Yen-Feng Wang,Jiing-Feng Lirng et al.
Yu-Hsiang Ling et al.
Background: Chronic headache may persist after the remission of reversible cerebral vasoconstriction syndrome (RCVS) in some patients. We aimed to investigate the prevalence, characteristics, risk factors, and the impact ...
Comparison of pregnenolone sulfate, pregnanolone and estradiol levels between patients with menstrually-related migraine and controls: an exploratory study [0.03%]
与正常人比较月经相关性偏头痛患者的脱氢表雄酮硫酸酯、孕烷醇酮和雌二醇水平的探索性研究
Cecilia Rustichelli,Elisa Bellei,Stefania Bergamini et al.
Cecilia Rustichelli et al.
Background: Neurosteroids affect the balance between neuroexcitation and neuroinhibition but have been little studied in migraine. We compared the serum levels of pregnenolone sulfate, pregnanolone and estradiol in women ...
Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2 [0.03%]
ATP1A2错义突变所致遗传性半侧空间忽视型偏头痛2型
Fabio Antonaci,Sabrina Ravaglia,Gaetano S Grieco et al.
Fabio Antonaci et al.
Background: The mechanisms of genotype-phenotype interaction in Familiar Hemiplegic migraine type 2 (FHM2) are still far from clear. Different ATP1A2 mutations have been described, with a spectrum of phenotypes ranging fr...
Different dosage regimens of Eptinezumab for the treatment of migraine: a meta-analysis from randomized controlled trials [0.03%]
艾普奈珠单抗不同给药方案治疗偏头痛的疗效和安全性：随机对照试验 Meta 分析
Zeya Yan,Tao Xue,Shujun Chen et al.
Zeya Yan et al.
Background: Migraine is one of the most common neurological diseases around the world and calcitonin gene-related peptide (CGRP) plays an important role in its pathophysiology. Therefore, in the present study, we evaluate...
Selective denervation of the corrugator supercilii muscle for the treatment of idiopatic trigeminal neuralgia purely paroxysmal distributed in the supraorbital and suprathrochlear dermatomes [0.03%]
选择性去神经支配皱眉肌治疗单纯局限于眶上、滑车上皮神经区域的原发性三叉神經痛患者
Alessandro Gualdi,Janos Cambiaso-Daniel,Jonatann Gatti et al.
Alessandro Gualdi et al.
Introduction: Idiopatic trigeminal neuralgia purely paroxysmal (ITNp) distributed in the supraorbital and suprathrochlear dermatomes (SSd), refractory to conventional treatments have been linked to the hyperactivity of th...
Structural brain network characteristics in patients with episodic and chronic migraine [0.03%]
发作性与慢性偏头痛患者的脑结构网络特征
Lars Michels,Nabin Koirala,Sergiu Groppa et al.
Lars Michels et al.
Background: Migraine is a primary headache disorder that can be classified into an episodic (EM) and a chronic form (CM). Network analysis within the graph-theoretical framework based on connectivity patterns provides an ...
Correction to: Impact of primary headache disorder on quality of life among school students in Kuwait [0.03%]
Correction to: 关于科威特学校学生原发性头痛疾病对生活质量影响的研究
Jasem Y Al-Hashel,R Alroughani,S Shuaibi et al.
Jasem Y Al-Hashel et al.
Published Erratum
The journal of headache and pain. 2021 Feb 14;22(1):7. DOI:10.1186/s10194-021-01217-7 2021
Effect of galcanezumab on severity and symptoms of migraine in phase 3 trials in patients with episodic or chronic migraine [0.03%]
伽卡奈珠单抗对发作性或慢性 migrainef患者的疗效三期临床试验结果分析：严重程度和症状改善情况
Michael Ament,Kathleen Day,Virginia L Stauffer et al.
Michael Ament et al.
Background: Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days compared with placebo. Here, we analyze data...