Altered amygdala effective connectivity in migraine without aura: evidence from resting-state fMRI with Granger causality analysis [0.03%]
无先兆偏头痛患者海马杏仁核有效连接的改变：基于静息态功能磁共振成像的格兰杰因果分析证据
Xiaobin Huang,Di Zhang,Peng Wang et al.
Xiaobin Huang et al.
Background: Granger causality analysis (GCA) has been used to investigate the pathophysiology of migraine. Amygdala plays a key role in pain modulation of migraine attack. However, the detailed neuromechanism remained to ...
The burden attributable to headache disorders in children and adolescents in Lithuania: estimates from a national schools-based study [0.03%]
立陶宛儿童和青少年头痛障碍的疾病负担估计：基于全国学校的研究结果
Diana Genc,Nerija Vaičienė-Magistris,Apolinaras Zaborskis et al.
Diana Genc et al.
Background: We recently showed headache to be common in children (aged 7-11 years) and adolescents (aged 12-17) in Lithuania. Here we provide evidence from the same study of the headache-attributable burden. ...
Petasin and isopetasin reduce CGRP release from trigeminal afferents indicating an inhibitory effect on TRPA1 and TRPV1 receptor channels [0.03%]
Petasin和Isopetasin通过抑制TRPA1和TRPV1通道来减少三叉神经传入CGRP的释放
Johanna Kleeberg-Hartmann,Birgit Vogler,Karl Messlinger
Johanna Kleeberg-Hartmann
Background: Butterbur root extract with its active ingredients petasin and isopetasin has been used in the prophylactic treatment of migraine for years, while its sites of action are not completely clear. Calcitonin gene-...
Reference programme: diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 3rd edition, 2020 [0.03%]
头痛与面部痛的诊断和治疗参考方案丹麦头痛协会 第三版 2020年发布
Henrik W Schytz,Faisal M Amin,Rigmor H Jensen et al.
Henrik W Schytz et al.
Headache and facial pain are among the most common, disabling and costly diseases in Europe, which demands for high quality health care on all levels within the health system. The role of the Danish Headache Society is to educate and advoca...
Comparative study of magnesium, sodium valproate, and concurrent magnesium-sodium valproate therapy in the prevention of migraine headaches: a randomized controlled double-blind trial [0.03%]
镁、丙戊酸钠以及联合应用镁和丙戊酸钠预防偏头痛的疗效比较：随机双盲临床试验
Samira Khani,Seyed Amir Hejazi,Mehdi Yaghoubi et al.
Samira Khani et al.
Objective: This study aimed to assess the efficacy of concurrent magnesium-sodium valproate therapy and compare it with either magnesium or sodium valproate alone in migraine prophylaxis. ...
Randomized Controlled Trial
The journal of headache and pain. 2021 Apr 7;22(1):21. DOI:10.1186/s10194-021-01234-6 2021
Reversible cerebral vasoconstriction syndrome (RCVS): an interesting case report [0.03%]
可逆性脑血管收缩综合征（RCVS）一例interesting病例报告
Mansoureh Togha,Mahsa Babaei,Parvin Ganji Ghelichi
Mansoureh Togha
Background: Reversible Cerebral Vasoconstriction Syndrome is a condition of transient cerebral vascular spasms, which usually presents with recurrent thunderclap headaches and recovers within 3 months. Several probable tr...
Advantages of imaging photoplethysmography for migraine modeling: new optical markers of trigemino-vascular activation in rats [0.03%]
基于影像的光容积描记法在偏头痛建模中的优势：新的三叉血管激活光学标志物研究（大鼠模型）
Alexey Y Sokolov,Maxim A Volynsky,Valery V Zaytsev et al.
Alexey Y Sokolov et al.
Background: Existent animal models of migraine are not without drawbacks and limitations. The aim of our study was to evaluate imaging photoplethysmography (PPG) as a method of assessing intracranial blood flow in rats an...
Peter J Goadsby,Michel Lantéri-Minet,Martin C Michel et al.
Peter J Goadsby et al.
Background: With headache experienced by up to 75% of adults worldwide in the last year, primary headache disorders constitute a major public health problem, yet they remain under-diagnosed and under-treated. Headache pre...
Effect of dural inflammatory soup application on activation and sensitization markers in the caudal trigeminal nucleus of the rat and the modulatory effects of sumatriptan and kynurenic acid [0.03%]
炎性脑脊液对大鼠三叉神经节后核活化和致敏标记物的影响及sumatriptan和Kynurenic酸的调节作用
Eleonóra Spekker,Klaudia Flóra Laborc,Zsuzsanna Bohár et al.
Eleonóra Spekker et al.
Background: The topical inflammatory soup can model the inflammation of the dura mater causing hypersensitivity and activation of the trigeminal system, a phenomenon present in migraineurs. Calcitonin gene-related peptide...
Safety and tolerability of eptinezumab in patients with migraine: a pooled analysis of 5 clinical trials [0.03%]
用于治疗偏头痛的eptinzumab的安全性和耐受性：五项临床试验的结果汇总分析
Timothy R Smith,Egilius L H Spierings,Roger Cady et al.
Timothy R Smith et al.
Background: The humanized anti-CGRP monoclonal antibody eptinezumab has been evaluated in five large-scale clinical trials conducted in patients with migraine. This integrated analysis was conducted to evaluate the compre...