Expert consensus on gepants for acute and preventive treatment of migraine in Thailand [0.03%]
泰国葛帕肽类药物急性及预防性治疗偏头痛专家共识
Prakit Anukoolwittaya,Wanakorn Rattanawong,Kiratikorn Vongvaivanich et al.
Prakit Anukoolwittaya et al.
Fibroblast reprogramming in the dura mater of NTG-induced migraine-related chronic hypersensitivity model drives monocyte infiltration via Angptl1-dependent stromal signaling [0.03%]
天疱疮诱导的偏头痛相关慢性高敏模型中成纤维细胞重编程通过Angptl1依赖性基质信号驱动单核细胞浸润
Guangyu Guo,Lei Zhang,Xuyang Liu et al.
Guangyu Guo et al.
Background: Migraine, characterized by recurrent episodes of severe headache, remains mechanistically enigmatic. While traditional theories emphasize trigeminovascular activation, the role of meningeal stromal-immune cros...
Association between headaches and lifestyle factors and physical and mental symptoms among 63,071 workers at a Japanese information technology company [0.03%]
日本一家信息技术公司的63071名员工的头痛与生活习惯及身心症状的相关性研究
Masako Yokoyama,Hisaka Igarashi,Hirohisa Kato et al.
Masako Yokoyama et al.
Background: Headaches are common and can significantly affect working conditions. To reduce their occurrence at work, identifying factors associated with headaches is important. We aimed to investigate the association bet...
Validation of an 8-item self-administered questionnaire for assessing migraine-related sensory hypersensitivities (MHQ-8) [0.03%]
一项用于评估与偏头痛相关的感官过敏性的自填调查问卷(MHQ-8)的有效性验证
François Gabrielli,Melissa Zuel,Camille Magaud et al.
François Gabrielli et al.
Background: In addition to headache, migraine patients often experience sensory hypersensitivity to external stimuli. While photophobia and phonophobia are part of the diagnostic criteria of migraine, many patients also e...
Ergotamine enhances circadian amplitude and diurnally mitigates nitroglycerin-induced mechanical hypersensitivity [0.03%]
麦角胺增强昼夜节律振幅并通过每日给药减轻硝酸甘油诱导的机械性超敏反应
Chorong Han,Hwayoung Baek,Ji Ye Lim et al.
Chorong Han et al.
Background: Cluster headache and migraine have a circadian timing of attacks and are linked to the trigeminovascular system. Recently the trigeminal ganglion was found to have a strong circadian rhythm, with the serotonin...
Unravelling the gut-brain connection: a systematic review of migraine and the gut microbiome [0.03%]
解开肠-脑联系:偏头痛与肠道微生物群的系统性综述
Caroline W Mugo,Ella Church,Richard D Horniblow et al.
Caroline W Mugo et al.
Background: There is substantial evidence linking migraines to gastrointestinal (GI) issues. Conditions such as irritable bowel syndrome and colitis often co-occur with migraines and GI symptoms are common among migraine ...
Reliability and validity of the Arabic version of cluster headache impact questionnaire in both active episodic and chronic cluster headache [0.03%]
阿拉伯语丛集性头痛影响调查问卷在各种丛集性头痛活动期的有效性和可靠性
Mona Hussein,Mona Af Nada,Amr Hassan et al.
Mona Hussein et al.
Background: Clinical evaluation of cluster headache (CH) impact on patients' quality of life is crucial in research and clinical practice. To our knowledge, none of the measures that evaluated CH-related disability were v...
Nuclear paraspeckle assembly transcript 1 promotes photophobia behavior in mice via miR-196a-5p/Trpm3 coupling [0.03%]
N核小体装配转录物1通过miR-196a-5p / Trpm3偶联促进小鼠畏光行为
Zhuoan Huang,Xingshen Li,Xiaolin Wang et al.
Zhuoan Huang et al.
Background: The long noncoding RNA, NEAT1, is recognized as a key regulator of proinflammatory gene expression; Yet, its functional role in migraine remains unexplored, despite the central role of neuroinflammatory mechan...
Genetic influence of the brain imaging phenotypes, brain and cerebrospinal fluid metabolites and brain genes on migraine subtypes: a Mendelian randomization and multi-omics study [0.03%]
基于孟德尔随机化和多组学研究探讨脑影像表型、脑脊液代谢物及脑基因对偏头痛亚型遗传影响的关联性分析
Ping-An Zhang,Jie-Lin Wang,Mei-Hua Dong et al.
Ping-An Zhang et al.
Background: Migraine is a complex neurological disorder with high prevalence but unclear pathogenesis. Numerous studies have suggested that migraine is associated with alterations in brain imaging phenotypes (BIPs) and dy...
Induction of more severe central sensitization in a medication overuse headache model mice through active ingestion of rizatriptan [0.03%]
佐米曲普坦主动摄入加重药物过度使用性头痛模型小鼠中枢敏化作用
Zhenjie Ma,Chenhao Li,Wenhao Bai et al.
Zhenjie Ma et al.
Background: Medication overuse headache (MOH) is a secondary headache disorder arising from excessive use of acute analgesics in patients with primary headache. Current animal models that predominantly employ passive drug...