The relationship between headache-attributed disability and lost productivity: 1. A review of the literature [0.03%]
头痛致残与生产力损失的关系：文献综述
Simple Futarmal Kothari,Rigmor Hølland Jensen,Timothy J Steiner
Simple Futarmal Kothari
Background: Headache disorders are disabling and have a significant impact on productivity. The relationship between these two consequences is of considerable economic and political interest. We enquired into it through a...
MAB-MIG: registry of the spanish neurological society of erenumab for migraine prevention [0.03%]
西班牙神经学学会的erenumab防治偏头痛登记处(MAB-MIG)
Robert Belvís,Pablo Irimia,Patricia Pozo-Rosich et al.
Robert Belvís et al.
Background: Erenumab was approved in Europe for migraine prevention in patients with ≥ 4 monthly migraine days (MMDs). In Spain, Novartis started a personalized managed access program, which allowed free access to erenum...
Cortical metabolic and structural differences in patients with chronic migraine. An exploratory 18FDG-PET and MRI study [0.03%]
慢性偏头痛患者皮质代谢和结构的差异：一项探索性的葡萄糖正电子发射断层扫描及磁共振成像研究
Marta Torres-Ferrus,Deborah Pareto,Victor J Gallardo et al.
Marta Torres-Ferrus et al.
Background: To describe interictal brain structural and metabolic differences between patients with episodic migraine (EM), chronic migraine (CM) and healthy controls (HC). ...
Assessment of normalized cerebral blood flow and its connectivity with migraines without aura during interictal periods by arterial spin labeling [0.03%]
动脉自旋标记测定无先兆偏头痛发作间期脑血流量及其连接性评估
Di Zhang,Xiaobin Huang,Cunnan Mao et al.
Di Zhang et al.
Background: Migraine constitutes a global health burden, and its pathophysiology is not well-understood; research evaluating cerebral perfusion and altered blood flow between brain areas using non-invasive imaging techniq...
Comorbidities of primary headache disorders: a literature review with meta-analysis [0.03%]
原发性头痛共病的文献复习及荟萃分析
Valeria Caponnetto,Manuela Deodato,Micaela Robotti et al.
Valeria Caponnetto et al.
Background: Primary headache disorders are common and burdensome conditions. They are associated to several comorbidities, such as cardiovascular or psychiatric ones, which, in turn, contribute to the global burden of hea...
Interleukin-6 induces spatially dependent whole-body hypersensitivity in rats: implications for extracephalic hypersensitivity in migraine [0.03%]
白细胞介素-6在大鼠中诱导空间依赖性的全身高敏反应：偏头痛的局灶性高敏感性意义
Amanda Avona,Theodore J Price,Gregory Dussor
Amanda Avona
Background: Migraine is a complex neurological disorder that is characterized by throbbing head pain, increased sensitivity to light, sound, and touch, as well as nausea and fatigue. It is one of the most common and most ...
High concurrent validity between digital and analogue algometers to measure pressure pain thresholds in healthy participants and people with migraine: a cross-sectional study [0.03%]
健康受试者和偏头痛患者中数字压痛计与模拟压痛计测量压力痛阈值的高并行效度：横断面研究
René F Castien,Michel W Coppieters,Tom S C Durge et al.
René F Castien et al.
Background: Pressure pain thresholds (PPTs) are commonly assessed to quantify mechanical sensitivity in various conditions, including migraine. Digital and analogue algometers are used, but the concurrent validity between...
Efficacy and safety of fremanezumab in patients with episodic and chronic migraine with documented inadequate response to 2 to 4 classes of migraine preventive medications over 6 months of treatment in the phase 3b FOCUS study [0.03%]
弗马佐单抗治疗对2～4种预防性治疗药物反应不足的 episodic 和慢性偏头痛患者的疗效和安全性：FOCUS III期临床研究
Messoud Ashina,Joshua M Cohen,Maja Galic et al.
Messoud Ashina et al.
Background: Fremanezumab, a fully humanized monoclonal antibody (IgG2Δa) selectively targets the calcitonin gene-related peptide and has proven efficacy for the preventive treatment of migraine. In this study, we evaluat...
The patients' perspective on the burden of idiopathic intracranial hypertension [0.03%]
IIH患者的角度看待其发病给患者带来的疾病负担
Max Witry,Christine Kindler,Johannes Weller et al.
Max Witry et al.
Background: Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure without evidence of a tumor or any other underlying cause. Headache and visual disturbances are frequent complaint...
Phenome-wide analysis highlights putative causal relationships between self-reported migraine and other complex traits [0.03%]
全表型组分析揭示了自述偏头痛与其他复杂性状之间潜在的因果关系
Luis M García-Marín,Adrián I Campos,Nicholas G Martin et al.
Luis M García-Marín et al.
Background: Migraine is a complex neurological disorder that is considered the most common disabling brain disorder affecting 14 % of people worldwide. The present study sought to infer potential causal relationships betw...