Jiajie Mo,Jianguo Zhang,Wenhan Hu et al.
Jiajie Mo et al.
Background: Novel neuroimaging strategies have the potential to offer new insights into the mechanistic basis for trigeminal neuralgia (TN). The present study aims to conduct whole-brain morphometry analyses of TN patient...
Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms [0.03%]
ATP1A2突变的临床表型谱与功能相关性:从纯运动型偏瘫型偏头痛到其变异型
Yingji Li,Wenjing Tang,Li Kang et al.
Yingji Li et al.
Background: Mutations in ATP1A2, the gene encoding the α2 subunit of Na+/K+-ATPase, are the main cause of familial hemiplegic migraine type 2 (FHM2). The clinical presentation of FHM2 with mutations in the same gene vari...
HMGB1, NLRP3, IL-6 and ACE2 levels are elevated in COVID-19 with headache: a window to the infection-related headache mechanism [0.03%]
COVID-19相关头痛患者的HMGB1、NLRP3、IL-6和ACE2水平升高:感染相关性头痛机制的窗口研究
Hayrunnisa Bolay,Ömer Karadas,Bilgin Oztürk et al.
Hayrunnisa Bolay et al.
Background and aim: Pathogenesis of COVID-19 -related headache is unknown, though the induction of the trigeminal neurons through inflammation is proposed. We aimed to investigate key systemic circulating inflammatory mol...
Acute prolonged motor aura resembling ischemic stroke after COVID - 19 vaccination (CoronaVac): the first case report [0.03%]
新型冠状病毒疫苗(科兴疫苗)接种后出现类似缺血性脑卒中的急性长时间运动先兆:首例报告
Wanakorn Rattanawong,Wasan Akaratanawat,Supatporn Tepmongkol et al.
Wanakorn Rattanawong et al.
Background: We report the first case of a patient who suffered transient focal neurological deficit mimicking stroke following CoronaVac vaccination. However, instead of an ischemic stroke, motor aura was suspected. ...
Regional cerebral blood flow as predictor of response to occipital nerve block in cluster headache [0.03%]
枕神经阻滞治疗丛集性头痛疗效的脑血流灌注预测模型研究
Sonia Medina,Norazah Abu Bakar,Owen ODaly et al.
Sonia Medina et al.
Background: Cluster headache is an excruciating disorder with no cure. Greater occipital nerve blockades can transiently suppress attacks in approximately 50% of patients, however, its mechanism of action remains uncertai...
Identifying genetic variants for age of migraine onset in a Han Chinese population in Taiwan [0.03%]
在台湾汉族人中鉴定偏头痛发病年龄的遗传变异型
Chia-Kuang Tsai,Chih-Sung Liang,Guan-Yu Lin et al.
Chia-Kuang Tsai et al.
Background: Considering the involvement of genetics in migraine pathogenesis in diverse ethnic populations, genome-wide association studies (GWAS) are being conducted to identify migraine-susceptibility genes. However, li...
Structured headache services as the solution to the ill-health burden of headache. 3. Modelling effectiveness and cost-effectiveness of implementation in Europe: findings and conclusions [0.03%]
有组织的头痛诊疗服务可解决头痛引起的疾病负担。第三部分:在欧洲实施此类服务的效果和成本效益模型分析结果及结论
Michela Tinelli,Matilde Leonardi,Koen Paemeleire et al.
Michela Tinelli et al.
Background: There have been several calls for estimations of costs and consequences of headache interventions to inform European public-health policies. In a previous paper, in the absence of universally accepted methodol...
The baton changed hands [0.03%]
权杖易手
Paolo Martelletti
Paolo Martelletti
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy [0.03%]
偏头痛中CGRP通路多态性的作用:系统性综述及其对CGRP单克隆抗体治疗的影响
Damiana Scuteri,Maria Tiziana Corasaniti,Paolo Tonin et al.
Damiana Scuteri et al.
Background: the interest of clinical reaseach in polymorphisms and epigenetics in migraine has been growing over the years. Due to the new era of preventative migraine treatment opened by monoclonal antibodies (mAbs) targ...
Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation [0.03%]
在复发性硝基甘油刺激后三叉神经脊束核微胶质细胞GLP-1R激活抑制慢性偏头痛的中枢敏化作用
Feng Jing,Qian Zou,Yangyang Wang et al.
Feng Jing et al.
Background: Central sensitization is considered a critical pathogenic mechanism of chronic migraine (CM). Activation of microglia in the trigeminal nucleus caudalis (TNC) contributes to this progression. Microglial glucag...