Temporal characteristics of astrocytic activation in the TNC in a mice model of pain induced by recurrent dural infusion of inflammatory soup [0.03%]
小鼠反复硬膜下输注炎症液诱发痛模型背根神经节星形胶质细胞激活的动态特征研究
Leyi Zhang,Chenglong Lu,Li Kang et al.
Leyi Zhang et al.
Background: Astrocytic activation might play a significant role in the central sensitization of chronic migraine (CM). However, the temporal characteristics of the astrocytic activation in the trigeminal nucleus caudalis ...
Altered effective connectivity in migraine patients during emotional stimuli: a multi-frequency magnetoencephalography study [0.03%]
情绪刺激下偏头痛患者的连接性改变:一种多频磁脑电图研究
Jing Ren,Qun Yao,Minjie Tian et al.
Jing Ren et al.
Background: Migraine is a common and disabling primary headache, which is associated with a wide range of psychiatric comorbidities. However, the mechanisms of emotion processing in migraine are not fully understood yet. ...
Noemi Meylakh,Luke A Henderson
Noemi Meylakh
Background: Migraine is a neurological disorder characterized by intense, debilitating headaches, often coupled with nausea, vomiting and sensitivity to light and sound. Whilst changes in sensory processes during a migrai...
Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists [0.03%]
TRPM3激动剂激活雄鼠和雌鼠脑膜感觉神经元的性别差异及与偏头痛的相关性
G Krivoshein,E A Tolner,Amjm van den Maagdenberg et al.
G Krivoshein et al.
Background: Migraine is a common brain disorder that predominantly affects women. Migraine pain seems mediated by the activation of mechanosensitive channels in meningeal afferents. Given the role of transient receptor po...
Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2 [0.03%]
针对发作性偏头痛和慢性偏头痛的外周生物标志物评估:以NGF、BDNF、VEGF和PGE2为重点的病例对照研究
Mohammad Mozafarihashjin,Mansoureh Togha,Zeinab Ghorbani et al.
Mohammad Mozafarihashjin et al.
Background: Several inflammatory and vascular molecules, and neurotrophins have been suggested to have a possible role in the development of migraine. However, pathophysiological events leading to migraine onset and trans...
IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine [0.03%]
IL-17诱导血脑屏障通透性增加进而触发nitroglycerin所致慢性偏头痛的新机制研究
Hao Chen,Xueqian Tang,Jin Li et al.
Hao Chen et al.
Background: Chronic migraine places a disabling burden on patients, which is extensively modeled by the nitroglycerin (NTG)-treated animal model. Although the NF-κB pathway is involved in an increase in CGRP levels and a...
Headache, anosmia, ageusia and other neurological symptoms in COVID-19: a cross-sectional study [0.03%]
一项横断面研究:新冠肺炎患者的头痛、嗅觉丧失、味觉丧失和其他神经系统症状
Pedro Augusto Sampaio Rocha-Filho,Pedro Mota Albuquerque,Larissa Clementino Leite Sá Carvalho et al.
Pedro Augusto Sampaio Rocha-Filho et al.
Background: Neurological symptoms are frequent among patients with COVID-19. Little is known regarding the repercussions of neurological symptoms for patients and how these symptoms are related to one another. ...
Deterioration of headache impact and health-related quality of life in migraine patients after cessation of preventive treatment with CGRP(-receptor) antibodies [0.03%]
停止使用CGRP(受体)抗体预防性治疗后偏头痛患者病情影响及与健康相关的生活质量恶化
Maria Terhart,Jasper Mecklenburg,Lars Neeb et al.
Maria Terhart et al.
Background: Migraine preventive treatment with CGRP(-receptor) monoclonal antibodies (mAbs) has a positive effect on patients' health-related quality of life (HRQoL). The German treatment guidelines recommend discontinuin...
Characteristics of N400 component elicited in patients who have migraine with aura [0.03%]
伴随偏头痛的先兆患者的N400成分的特点分析
Igor Petrusic,Vojislav Jovanovic,Vanja Kovic et al.
Igor Petrusic et al.
Background: This study aimed to examine the N400 effect and event-related potentials (ERPs) elicited from congruent and incongruent stimuli in patients who have migraines with aura (MwA). ...
Is there a causal relationship between stress and migraine? Current evidence and implications for management [0.03%]
压力与偏头痛之间存在因果关系吗?当前的证据及对治疗的意义
Anker Stubberud,Dawn C Buse,Espen Saxhaug Kristoffersen et al.
Anker Stubberud et al.
Background: The purpose of this narrative review is to examine the literature investigating a causal relationship between stress and migraine and evaluate its implications for managing migraine. ...