Comparing the relative and absolute effect of erenumab: is a 50% response enough? Results from the ESTEEMen study [0.03%]
ERENUMAB的相对和绝对效应比较：50%的反应足够吗？来自ESTEEMen研究的结果
Raffaele Ornello,Carlo Baraldi,Simona Guerzoni et al.
Raffaele Ornello et al.
Background: Monoclonal antibodies acting on the calcitonin gene-related peptide (CGRP) or its receptor have changed migraine preventive treatment. Those treatments have led to reconsidering the outcomes of migraine preven...
Comparative Study
The journal of headache and pain. 2022 Mar 19;23(1):38. DOI:10.1186/s10194-022-01408-w 2022
Cluster Headache Impact Questionnaire (CHIQ) - a short measure of cluster headache related disability [0.03%]
簇头痛影响问卷(CHIQ)-一种测量与簇头痛相关的残疾的简短量表
Katharina Kamm,Andreas Straube,Ruth Ruscheweyh
Katharina Kamm
Background: Cluster headache (CH) is a severe, highly disabling primary headache disorder. However, there is little research on CH-related disability, and most of it is based on non CH-specific questionnaires. The aim of ...
Migraine susceptibility is modulated by food triggers and analgesic overuse via sulfotransferase inhibition [0.03%]
migraines的发生通过硫转移酶的抑制作用受食物触发和止痛药过度使用调节
Doga Vuralli,Burak Arslan,Elif Topa et al.
Doga Vuralli et al.
Background/aim: Certain constituents in migraine food triggers and non-steroidal anti-inflammatory drugs (NSAIDs) inhibit sulfotransferases (SULTs) that detoxify drugs/chemicals and play role in the metabolism of neurotra...
Calcitonin gene-related peptide receptor antagonist BIBN4096BS regulates synaptic transmission in the vestibular nucleus and improves vestibular function via PKC/ERK/CREB pathway in an experimental chronic migraine rat model [0.03%]
针对慢性偏头痛的大鼠模型研究BIBN4096BS对前庭核突触传递的调节作用及改善前庭功能机制
Ruimin Tian,Yun Zhang,Qi Pan et al.
Ruimin Tian et al.
Background: Vestibular symptoms are frequently reported in patients with chronic migraine (CM). However, whether vestibular symptoms arise through overlapping neurobiology of migraine remains to be elucidated. The neurope...
Time is of the essence in headache measurement. A response to Gil-Gouveia [0.03%]
头痛测量的时间至关重要。对Gil-Gouveia的回应
T J Steiner
T J Steiner
Correction to: Hyperbaric oxygen attenuates neuropathic pain and reverses inflammatory signaling likely via the Kindlin-1/Wnt-10a signaling pathway in the chronic pain injury model in rats [0.03%]
Correction to: 高压氧减轻大鼠慢性疼痛模型神经病理性疼痛并通过Kindlin-1/Wnt-10a信号通路逆转炎症信号
Baisong Zhao,Yongying Pan,Haiping Xu et al.
Baisong Zhao et al.
Published Erratum
The journal of headache and pain. 2022 Mar 4;23(1):32. DOI:10.1186/s10194-022-01407-x 2022
TIME, to move forward? comment on "a universal outcome measure for headache treatments, care-delivery systems and economic analysis" [0.03%]
时间向前？对“偏头痛治疗、医疗服务系统及经济分析的普遍结果测量方法”的评论
Raquel Gil-Gouveia
Raquel Gil-Gouveia
The paper from Steiner et al. suggests that an outcome measure expressed in time units may be an adequate method to assess the impact of headache disorders, regardless of diagnosis or health care setting, proving useful for cost-benefit ana...
Early response to eptinezumab indicates high likelihood of continued response in patients with chronic migraine [0.03%]
埃普替奈珠单抗早期治疗效果良好可预测慢性偏头痛患者的持续反应率较高
Dawn C Buse,Paul K Winner,Larry Charleston th et al.
Dawn C Buse et al.
Background: A clinical ability to describe the response trajectory of patients receiving preventive migraine treatment could expedite and improve therapeutic management decisions. This post hoc analysis of the PROMISE-2 s...
Randomized Controlled Trial
The journal of headache and pain. 2022 Feb 21;23(1):29. DOI:10.1186/s10194-022-01387-y 2022
Dual action of the cannabinoid receptor 1 ligand arachidonyl-2'-chloroethylamide on calcitonin gene-related peptide release [0.03%]
麻风药Arachidonyl-2'-氯乙胺对calcitonin基因相关肽释放的双重作用
Isabella Mai Christiansen,Jacob C A Edvinsson,Philip V Reducha et al.
Isabella Mai Christiansen et al.
Background: Based on the current understanding of the role of neuropeptide signalling in migraine, we explored the therapeutic potential of a specific cannabinoid agonist. The aim of the present study was to examine the e...
Effectiveness and acceptability of noninvasive brain and nerve stimulation techniques for migraine prophylaxis: a network meta-analysis of randomized controlled trials [0.03%]
非侵入性脑和神经刺激技术预防偏头痛有效性和可接受性的网络meta分析：随机对照试验证据
Yu-Chen Cheng,Bing-Yan Zeng,Chao-Ming Hung et al.
Yu-Chen Cheng et al.
Background: Current pharmacologic prophylactic strategies for migraine have exhibited limited efficacy, with response rates as low as 40%-50%. In addition to the limited efficacy, the acceptability of those pharmacologic ...