Real-world effectiveness of fremanezumab in migraine patients initiating treatment in the United States: results from a retrospective chart study [0.03%]
法瑞莫治疗美国成人偏头痛患者的疗效和安全性：一项基于医疗记录的回顾性研究
Maurice T Driessen,Joshua M Cohen,Oscar Patterson-Lomba et al.
Maurice T Driessen et al.
Background: The efficacy and tolerability of fremanezumab, a fully humanized monoclonal antibody (IgG2Δa) that selectively targets calcitonin gene-related peptide (CGRP) and is approved for the preventive treatment of mi...
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates [0.03%]
全球头痛流行病学的更新及方法学因素对患病率估计影响的分析
Lars Jacob Stovner,Knut Hagen,Mattias Linde et al.
Lars Jacob Stovner et al.
Background: According to the Global Burden of Disease (GBD) study, headache disorders are among the most prevalent and disabling conditions worldwide. GBD builds on epidemiological studies (published and unpublished) whic...
Fremanezumab in the prevention of high-frequency episodic and chronic migraine: a 12-week, multicenter, real-life, cohort study (the FRIEND study) [0.03%]
一项为期12周的多中心真实世界队列研究：富马佐单抗用于高频发作性偏头痛和慢性偏头痛的预防（FRIEND研究）
Piero Barbanti,Gabriella Egeo,Cinzia Aurilia et al.
Piero Barbanti et al.
Background: Fremanezumab has demonstrated to be effective, safe, and tolerated in the prevention of episodic or chronic migraine (CM) in randomized, placebo-controlled trials (RCTs). Real-life studies are needed to explor...
Multicenter Study
The journal of headache and pain. 2022 Apr 9;23(1):46. DOI:10.1186/s10194-022-01396-x 2022
Abnormalities in resting-state EEG microstates are a vulnerability marker of migraine [0.03%]
静息态EEG微状态异常是偏头痛的脆弱性标志
Yansong Li,Guoliang Chen,Jing Lv et al.
Yansong Li et al.
Background: Resting-state EEG microstates are thought to reflect brief activations of several interacting components of resting-state brain networks. Surprisingly, we still know little about the role of these microstates ...
Involvement of adenosine signaling pathway in migraine pathophysiology: a systematic review of preclinical studies [0.03%]
腺苷信号通路在偏头痛发病机制中的作用：系统性回顾研究
Janu Thuraiaiyah,Lili Kokoti,Mohammad Al-Mahdi Al-Karagholi et al.
Janu Thuraiaiyah et al.
Background: Adenosine is a purinergic signaling molecule with a wide range of physiological functions including anti- and pronociceptive properties. Adenosine receptors are expressed in the trigeminovascular system, and a...
Attenuated alpha oscillation and hyperresponsiveness reveals impaired perceptual learning in migraineurs [0.03%]
衰减的α振荡和过度反应可揭示偏头痛患者的感知学习障碍
Chun Yuen Fong,Wai Him Crystal Law,Johannes Jacobus Fahrenfort et al.
Chun Yuen Fong et al.
Background: Anomalous phantom visual perceptions coupled to an aversion and discomfort to some visual patterns (especially grating in mid-range spatial frequency) have been associated with the hyperresponsiveness in migra...
FKN/CX3CR1 axis facilitates migraine-Like behaviour by activating thalamic-cortical network microglia in status epilepticus model rats [0.03%]
FKN/CX3CR1轴通过激活局灶性癫痫发作模型大鼠丘脑-皮层网络小胶质细胞来促进偏头痛样行为
Yanjie Zhou,Lily Zhang,Yuyan Hao et al.
Yanjie Zhou et al.
Background: The incidence of migraines is higher among individuals with epilepsy than in healthy individuals, and these two diseases are thought to shared pathophysiological mechanisms. Excitation/inhibition imbalance pla...
Headache onset after vaccination against SARS-CoV-2: a systematic literature review and meta-analysis [0.03%]
新型冠状病毒疫苗接种后的头痛：系统文献回顾和meta分析研究
Matteo Castaldo,Marta Waliszewska-Prosół,Maria Koutsokera et al.
Matteo Castaldo et al.
Background: Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are used to reduce the risk of developing Coronavirus Disease 2019 (COVID-19). Despite the significant benefits in terms of reduced...
Resumption of migraine preventive treatment with CGRP(-receptor) antibodies after a 3-month drug holiday: a real-world experience [0.03%]
降钙素基因相关肽(受体)抗体预防性治疗偏头痛停药3个月后的再次使用：真实世界经验
Bianca Raffaelli,Maria Terhart,Jasper Mecklenburg et al.
Bianca Raffaelli et al.
Background: Migraine frequency increases after the cessation of successful preventive treatment with CGRP(-receptor) monoclonal antibodies (mAbs). In this study, we aimed to evaluate the course of migraine after treatment...
Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs [0.03%]
全基因组分析鉴定出与偏头痛患者不安腿综合征易感性相关的新型候选基因
Yun-Jin Jiang,Cathy Shen-Jang Fann,Jong-Ling Fuh et al.
Yun-Jin Jiang et al.
Background: Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain unclear. Objectives: ...