Increased risk of all-cause, Alzheimer's, and vascular dementia in adults with migraine in Korea: a population-based cohort study [0.03%]
韩国成人偏头痛患者全因、阿尔茨海默病和血管性痴呆的患病风险增加：基于人口的队列研究
Kyungduk Hurh,Sung Hoon Jeong,Seung Hoon Kim et al.
Kyungduk Hurh et al.
Background: Studies investigating the association between migraine and dementia have reported inconsistent findings. This study aimed to evaluate whether patients with migraine have an increased risk of dementia compared ...
Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation [0.03%]
皮层弥散性抑制造成感觉刺激诱发小鼠脑aura的一个机制性认识
Sahin Hanalioglu,Aslihan Taskiran-Sag,Hulya Karatas et al.
Sahin Hanalioglu et al.
Background: Unlike the spontaneously appearing aura in migraineurs, experimentally, cortical spreading depression (CSD), the neurophysiological correlate of aura is induced by non-physiological stimuli. Consequently, neur...
Cédric Gollion,Fleur Lerebours,Federico Nemmi et al.
Cédric Gollion et al.
Introduction: Insula plays an integrating role in sensory, affective, emotional, cognitive and autonomic functions in migraine, especially in migraine with aura (MA). Insula is functionally divided into 3 subregions, the ...
Persistent headache after first-ever ischemic stroke: clinical characteristics and factors associated with its development [0.03%]
首次缺血性卒中后的持续性头痛：临床特点及影响因素分析
Elena R Lebedeva,Anton V Ushenin,Natalia M Gurary et al.
Elena R Lebedeva et al.
Background: It is poorly described how often headache attributed to stroke continues for more than 3 months, i.e. fulfils the criteria for persistent headache attributed to ischemic stroke. Our aims were: 1) to determine ...
Safety and tolerability of erenumab in individuals with episodic or chronic migraine across age groups: a pooled analysis of placebo-controlled trials [0.03%]
不同年龄段偏头痛患者使用erenumab的耐受性和安全性：安慰剂对照试验中的汇总分析
Christian Lampl,Viktoria Kraus,Katrina Lehner et al.
Christian Lampl et al.
Background: Erenumab, a fully human monoclonal antibody that targets the calcitonin gene-related peptide receptor, has demonstrated efficacy and safety in the prevention of episodic and chronic migraine. There exists an u...
HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain [0.03%]
外周神经损伤诱发的慢性疼痛丘脑前扣带回HMGB1介导的共病焦虑病理学机制研究
Yu Du,Ceng-Lin Xu,Jie Yu et al.
Yu Du et al.
Background: Whether neuroinflammation causes comorbid mood disorders in neuropathic pain remains elusive. Here we investigated the role of high mobility group box 1 protein (HMGB1), a proinflammatory cytokine, in the medi...
Post-COVID-19 neuropsychiatric manifestations among COVID-19 survivors suffering from migraine: a case-control study [0.03%]
一项关于新冠幸存者的病例对照研究：新冠病毒感染者发生偏头痛后的神经系统表现
Rehab Magdy,Alaa Elmazny,Shaimaa H Soliman et al.
Rehab Magdy et al.
Background: The burden of post-coronavirus disease (COVID)-19 symptoms has been increasing and is of great concern in patients with pre-existing chronic medical conditions.This study aimed to delineate the post-COVID-19 n...
Applying a biopsychosocial model to migraine: rationale and clinical implications [0.03%]
生物-心理-社会模型在偏头痛治疗中的应用：合理性及临床意义
Chiara Rosignoli,Raffaele Ornello,Agnese Onofri et al.
Chiara Rosignoli et al.
Migraine is a complex condition in which genetic predisposition interacts with other biological and environmental factors determining its course. A hyperresponsive brain cortex, peripheral and central alterations in pain processing, and com...
Avoid or seek light - a randomized crossover fMRI study investigating opposing treatment strategies for photophobia in migraine [0.03%]
避光或追光？一项针对偏头痛的畏光症的对立治疗策略的功能磁共振随机交叉试验研究
Eva Matt,Tuna Aslan,Ahmad Amini et al.
Eva Matt et al.
Background: Photophobia, the aberrantly increased sensitivity to light, is a common symptom in migraine patients and light discomfort is frequently found as a trigger for migraine attacks. In behavioral studies, planned e...
Randomized Controlled Trial
The journal of headache and pain. 2022 Aug 11;23(1):99. DOI:10.1186/s10194-022-01466-0 2022
Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine [0.03%]
多巴胺受体D2通过PI3K信号通路调节GLUA1型AMPA受体转运和中枢敏化在雄性慢性偏头痛大鼠模型中的作用研究
Wei Zhang,Ming Lei,Qianwen Wen et al.
Wei Zhang et al.
Background: The pathogenesis of chronic migraine remains unresolved. Recent studies have affirmed the contribution of GLUA1-containing AMPA receptors to chronic migraine. The dopamine D2 receptor, a member of G protein-co...