Promoter demethylation of cerebellin 2 by ten-eleven translocation 3 contributes to peripheral sensitization in trigeminal neuropathic pain of mice [0.03%]
Tet3介导的小脑肽2启动子去甲基化在三叉神经病理性痛外周敏化中的作用
Xin-Ying Guan,Bao-Tong Yuan,Meng-Na Li et al.
Xin-Ying Guan et al.
Background: Chronic neuropathic pain involves complex molecular adaptations, and emerging evidence indicates that cerebellins (CBLNs) play a role in sensory processing. This study investigates the role of CBLN2 in trigemi...
Headaches and family planning: insights from a Japanese school-based survey [0.03%]
日本学校-Based调查的头痛与计划生育的见解
Masahito Katsuki,Naomichi Wada,Keiko Iijima et al.
Masahito Katsuki et al.
Objective: To investigate the effect of headaches on women's pregnancy plans and fertility intentions. Methods: We prospectively perfor...
Comparing eptinezumab with onabotulinumtoxinA in the treatment of chronic migraine: a real-world evidence study [0.03%]
伊匹ネズマブとオンボツリヌ毒素Aの慢性片頭痛治療効果の実世界比較研究
Damiana Scuteri,Martina Pagliaro,Rosario Iannacchero et al.
Damiana Scuteri et al.
Background: Migraine, a spectrum of episodic headache disorders common in the global population, may evolve into a very debilitating chronic condition, usually underdiagnosed, poorly recognized and difficult to manage. Ne...
Spi1 aggravates neuropathic pain by modulating Clec7a-mediated neuroinflammation and microglial phagocytosis [0.03%]
Spi1通过调节Clec7a介导的神经炎症和小胶质细胞吞噬作用来加重神经病理性疼痛
Yin Xu,Xinli Liu,Hui Chen et al.
Yin Xu et al.
Background: Microglia are essential in mediating responses to nerve injury, with neuroinflammation and engulfment of interneuron inhibitory synapses driving heightened neuronal excitability and pain hypersensitivity. Spi1...
Micah Johnson,Yassine Filali,Anjayooluwa Adegboyo et al.
Micah Johnson et al.
It has long been recognized that there are comorbidities between migraine and psychiatric disorders, especially major depressive disorder (MDD). Often this relationship is attributed to the psychological risk of having an intermittent debil...
Do headaches impact pregnancy planning behaviors? A cross-sectional school-based study in Japan [0.03%]
日本一项基于学校的横断面研究：头痛会影响怀孕计划行为吗？
Masahito Katsuki,Yasuhiko Matsumori,Muneto Tatsumoto et al.
Masahito Katsuki et al.
Objective: Headache disorders are a common neurological disease with socioeconomic burdens among individuals of reproductive age, yet little is known about its impact on fertility intentions. This study examined the assoc...
White matter tract differences in persistent post-traumatic headache, migraine, and healthy controls: a diffusion tensor imaging study [0.03%]
扩散张量成像对持续性创伤后头痛、偏头痛和健康对照组患者弥散张量影像的白质束差异研究
Rune Häckert Christensen,Haidar Muhsen Al-Khazali,Cédric Gollion et al.
Rune Häckert Christensen et al.
Background: Persistent post-traumatic headache (PPTH) frequently resembles migraine but may involve distinct white matter perturbations. We compared white matter fiber tracts among adults with PPTH, migraine, and healthy ...
Shared neural signatures of photophobia in migraine and post-traumatic headache: a task-based fMRI study [0.03%]
偏头痛和创伤后头痛的光敏感共病：一项基于任务的功能磁共振研究
Rune Häckert Christensen,Haidar Muhsen Al-Khazali,Anna Gudrun Melchior et al.
Rune Häckert Christensen et al.
Background: Persistent post-traumatic headache (PTH) and migraine frequently present with photic hypersensitivity that exacerbates headache symptoms. We sought to determine whether persistent PTH is associated with altere...
Prevalence, characteristics and management of migraine patients with triptan failure in primary care: the EMR France-Mig study [0.03%]
法国初级医疗人群中曲普坦治疗失败的偏头痛患者的患病率、特征和处理情况：EMR France-Mig研究
M Lanteri-Minet,C Casarotto,O Bretin et al.
M Lanteri-Minet et al.
Background: The most used treatments for migraine attacks are triptans, yet a considerable proportion of the population develops treatment failure over time due to ineffectiveness, side effects, and/or contraindications. ...
High prevalence of primary headaches among patients with post-traumatic stress disorder: an observational study of consecutive patients [0.03%]
一项关于创伤后应激障碍患者的观察性研究：头痛在创伤后应激障碍患者中的高发病率
Hugues Magne,Bruno Pereira,Xavier Moisset
Hugues Magne
Background: Primary headaches affect between 40% and 50% of people worldwide and are linked to a range of medical and mental health conditions, including post-traumatic stress disorder (PTSD). Our objective is to assess t...