Exploring sensory sensitivity, cortical excitability, and habituation in episodic migraine, as a function of age and disease severity, using the pattern-reversal task [0.03%]
探索阵发性偏头痛的感觉敏感性、皮层兴奋性和适应性的年龄和疾病严重度依赖的特征：模式反转任务研究
Angela Marti-Marca,Adrià Vilà-Balló,Xim Cerda-Company et al.
Angela Marti-Marca et al.
Background: Migraine is a cyclic, neurosensory disorder characterized by recurrent headaches and altered sensory processing. The latter is manifested in hypersensitivity to visual stimuli, measured with questionnaires and...
Galcanezumab in patients with episodic migraine: results from the open-label period of the phase 3 PERSIST study [0.03%]
偏头痛发作期患者的Galcanezumab治疗：III期PERSIST研究开放标签期间的结果
Jiying Zhou,Lianmei Zhong,Debashish Chowdhury et al.
Jiying Zhou et al.
Background: The phase 3 randomized PERSIST study demonstrated the efficacy and tolerability of galcanezumab, a humanized anti-calcitonin gene-related peptide (CGRP) monoclonal antibody for prevention of episodic migraines...
Randomized Controlled Trial
The journal of headache and pain. 2023 Aug 4;24(1):103. DOI:10.1186/s10194-023-01613-1 2023
Real-world effectiveness, satisfaction, and optimization of ubrogepant for the acute treatment of migraine in combination with onabotulinumtoxinA: results from the COURAGE Study [0.03%]
用于偏头痛急性治疗的 ubrogepant 与 OnabotulinumtoxinA 联合应用的效果、满意度及优化：来自 COURAGE 研究的结果
Aubrey Manack Adams,Susan Hutchinson,Ella Engstrom et al.
Aubrey Manack Adams et al.
Background: Individuals using onabotulinumtoxinA as a preventive migraine treatment often use acute treatments for breakthrough attacks. Data on real-world effectiveness of the small-molecule calcitonin gene-related pepti...
Observational Study
The journal of headache and pain. 2023 Aug 3;24(1):102. DOI:10.1186/s10194-023-01622-0 2023
Persistence to anti-CGRP monoclonal antibodies and onabotulinumtoxinA among patients with migraine: a retrospective cohort study [0.03%]
一种单克隆抗体和onabotulinumtoxinA治疗偏头痛患者的持久性：一项回顾性队列研究
Larry Charleston th,Brian Talon,Christine Sullivan et al.
Larry Charleston th et al.
Background: To date, real-world evidence on persistence to anti-calcitonin gene-related peptide (anti-CGRP) monoclonal antibodies (mAbs) or onabotulinumtoxinA have excluded eptinezumab. This retrospective cohort study was...
Adrian Scutelnic,Hristina Drangova,Antonia Klein et al.
Adrian Scutelnic et al.
Aim: Given the similar presentation of migraine aura and acute ischemic stroke, advancing patient age might change the characteristics of migraine with aura (MA) and be clinically important. Clinical data, however, are li...
Ten open questions in migraine prophylaxis with monoclonal antibodies blocking the calcitonin-gene related peptide pathway: a narrative review [0.03%]
靶向降钙素基因相关肽通路的单克隆抗体治疗偏头痛预防的十大待决问题：叙述性综述
Jean Schoenen,Annelies Van Dycke,Jan Versijpt et al.
Jean Schoenen et al.
The monoclonal antibodies (mAbs) blocking the calcitonin-gene related peptide (CGRP) pathway, collectively called here "anti-CGRP/rec mAbs", have dramatically improved preventive migraine treatment. Although their efficacy and tolerability ...
A higher probability of subsequent stroke and ischemic heart disease in migraine patients: a longitudinal follow-up study in Korea [0.03%]
韩国一项关于偏头痛患者的后续研究：卒中和缺血性心脏病的发生概率更高
Mi Jung Kwon,Hyo Geun Choi,Yoo Hwan Kim et al.
Mi Jung Kwon et al.
Background: Whether migraine is related to the risk of cardiovascular diseases (CVDs) remains unclear. Therefore, we conducted a longitudinal follow-up study to address the association between migraine and the development...
MRI features of idiopathic intracranial hypertension are not prognostic of visual and headache outcome [0.03%]
特发性颅内高压的MRI特征不能预示视觉及头痛转归
Gabriel Bsteh,Wolfgang Marik,Nik Krajnc et al.
Gabriel Bsteh et al.
Background: In idiopathic intracranial hypertension (IIH), certain MRI features are promising diagnostic markers, but whether these have prognostic value is currently unknown. ...
2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study [0.03%]
生酮饮食和低血糖指数饮食治疗慢性偏头痛和发作性偏头痛的疗效：一项单中心真实世界回顾性研究
Yan Tereshko,Simone Dal Bello,Cherubino Di Lorenzo et al.
Yan Tereshko et al.
Aims: The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding the ketogenic diet. However, less evidence exists for the Low-Glycemic Index Diet and the 2:1 KD. This...
Optogenetic cortical spreading depolarization induces headache-related behaviour and neuroinflammatory responses some prolonged in familial hemiplegic migraine type 1 mice [0.03%]
光遗传皮层扩散去极化诱导偏瘫型家族性偏头痛小鼠的头痛行为和神经炎症反应并持续一段时间
Anisa Dehghani,Maarten Schenke,Sandra H van Heiningen et al.
Anisa Dehghani et al.
Background: Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain pathways, but the neurobiological mechanisms and behavioural consequences remain unc...