An AI-based nomogram (the CGRP score) for the prediction of response to modern migraine therapies: an independent assessment and some considerations on the application of AI tools in clinical setting [0.03%]
一种基于人工智能的预测偏头痛现代治疗反应的列线图（CGRP评分）：独立评估及临床环境中应用AI工具的一些考虑事项
Danilo Antonio Montisano,Licia Grazzi,Alberto Raggi
Danilo Antonio Montisano
The medial orbitofrontal cortex mediates neuropathic pain and anxiodepressive-like behaviors via two distinct pathways [0.03%]
内侧眶额皮质通过两条不同的通路介导神经病理性疼痛和类似焦虑抑郁的行为
Zhixiao Li,Tianen Si,Liangliang Gao et al.
Zhixiao Li et al.
Background: Chronic neuropathic pain is frequently accompanied by anxiety and depression, yet the cortical circuit mechanisms underlying this comorbidity remain unclear. The medial orbitofrontal cortex (mOFC) is a key cor...
Temporal and regional trends in the diagnosis and treatment of spontaneous intracranial hypotension: a systematic review [0.03%]
自发性颅内低压的诊断和治疗的趋势：系统评价
Woo-Seok Ha,Soyoun Choi,Mi-Kyoung Kang et al.
Woo-Seok Ha et al.
Prefrontal dysregulation of interoceptive and emotional processing in episodic migraine: a task-based fMRI study [0.03%]
发作性偏头痛患者内感受和情感处理的前额叶调节障碍：一项任务态功能磁共振成像研究
Yuanxiang Li,Ruihua Liu,Cunxin Lin et al.
Yuanxiang Li et al.
Background: Migraine is a complex sensory processing disorder marked by dysfunctions in both exteroception and interoception. The high frequency of emotional comorbidities suggests significant abnormalities in emotional p...
Evolution of use and overuse of triptans in Austria - What has changed in the last 15 years? [0.03%]
奥地利十几年来曲普坦类药物使用和滥用的变化趋势分析
Katharina Kaltseis,Sarah Maier,Karin Zebenholzer et al.
Katharina Kaltseis et al.
Functional connectome gradient alterations in herpes zoster and postherpetic neuralgia: associations with gene expression profiles [0.03%]
带状疱疹和带状疱疹后神经痛的功能连接组变化及基因表达特征分析
Jiaxin Xiong,Xiao Liang,Chen Yang et al.
Jiaxin Xiong et al.
Predictive factors of effectiveness of occipital nerve stimulation for chronic cluster headache: data from for the French ONS registry [0.03%]
法国后枕神经刺激注册中心慢性丛集性头痛患者的疗效预测因素分析
Denys Fontaine,Roxane Fabre,Aurelie Leplus et al.
Denys Fontaine et al.
BOLD repetition enhancement in the orbitofrontal cortex during complex visuospatial processing in migraine without aura: a shift in periaqueductal gray - cortical coupling? [0.03%]
无先兆偏头痛期间在复杂视空间处理过程中眶额皮质的重复性增强：脑导水管周围灰质-皮层耦合模式改变？
Zeynep Ceren Onlat,Sertac Ustun,Ilkem Guzel et al.
Zeynep Ceren Onlat et al.
Background: Visual discomfort and sensory overload are common complaints in migraine patients without aura (MwoA), even between attacks, yet their neural basis remains poorly understood. We aimed to explore brain activati...
S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis [0.03%]
S100A11通过H3K27ac-TFEB-线粒体自噬轴调节神经病理性疼痛小胶质细胞炎症反应
Heqing Zheng,Sheng Tian,Lanxiang Wu et al.
Heqing Zheng et al.
Neuropathic pain (NP) is tightly linked to spinal microglial overactivation, sustained neuroinflammation; however, the key molecular regulators and epigenetic circuitry driving microglial functional dyshomeostasis remain incompletely define...
Anti-CGRP receptor antibodies do not modulate trigeminal pain processing: indication for distinct mechanisms of CGRP pathway blockade [0.03%]
抗CGRP受体抗体不会调节三叉神经痛处理：表明CGRP通路阻断的机制不同
Kuan-Po Peng,Hauke Basedau,Karl Messlinger et al.
Kuan-Po Peng et al.
Background: Monoclonal antibodies (mAbs) targeting calcitonin gene-related peptides (CGRP) are established therapies for migraine. There are currently four CGRP-mAbs available on the market: one targets the CGRP receptor,...