Haidar M Al-Khazali,Håkan Ashina,Astrid Wiggers et al.
Haidar M Al-Khazali et al.
Background: Although the involvement of calcitonin gene-related peptide (CGRP) in migraines is well-established, its specific role in investigating the aura phase, which often precedes the headache, remains largely unexpl...
Investigating the relationship between sleep and migraine in a global sample: a Bayesian cross-sectional approach [0.03%]
从全球样本调查睡眠和偏头痛之间的关系：贝叶斯横断面研究方法
Emily C Stanyer,Jack Brookes,Jia Rong Pang et al.
Emily C Stanyer et al.
Background: There is a bidirectional link between sleep and migraine, however causality is difficult to determine. This study aimed to investigate this relationship using data collected from a smartphone application. ...
Proteomics profiling reveals mitochondrial damage in the thalamus in a mouse model of chronic migraine [0.03%]
蛋白组学分析揭示慢性偏头痛小鼠模型丘脑中线粒体损伤
Wei Xie,Ruibing Li,Wenjing Tang et al.
Wei Xie et al.
Background: Migraine, a complex brain disorder, is regarded as a possible clinical manifestation of brain energy dysfunction. The trigeminovascular system is considered the basis for the pathogenesis of migraine, hence we...
Current treatment options for cluster headache: limitations and the unmet need for better and specific treatments-a consensus article [0.03%]
丛集性头痛的当前治疗选择：限制因素及对更好更特异性治疗方法的需求——共识文章
Nunu Laura Timotheussen Lund,Anja Sofie Petersen,Rolf Fronczek et al.
Nunu Laura Timotheussen Lund et al.
Aim: Treatment for cluster headache is currently based on a trial-and-error approach. The available preventive treatment is unspecific and based on few and small studies not adhering to modern standards. Therefore, the au...
Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China [0.03%]
中国原发性头痛障碍的诊断和预防现状：真实世界中的未尽需求
Huanxian Liu,Ming Dong,Kaiming Liu et al.
Huanxian Liu et al.
Background: Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misdiagnosis and inadequate treatment of primary headache disorders remain significant chal...
Who cares about migraine? Pathways and hurdles in the European region - access to care III [0.03%]
谁在意偏头痛？欧洲地区的途径与障碍——获取医疗保障第三部分
Gloria Vaghi,Roberto De Icco,Cristina Tassorelli et al.
Gloria Vaghi et al.
Background: Migraine is a highly prevalent primary headache disorder and a leading cause of disability. Difficulties in access to care during diagnostic and therapeutic journey contribute to the disease burden. Several ta...
Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study [0.03%]
慢性偏头痛患者皮层过敏预示治疗反应的队列研究
Judith A Pijpers,Dennis A Kies,Erik W van Zwet et al.
Judith A Pijpers et al.
Background: Central sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third order neurons sequentially, resulting in an analogous spatial distribution of cutaneous a...
Randomized Controlled Trial
The journal of headache and pain. 2023 Aug 30;24(1):118. DOI:10.1186/s10194-023-01651-9 2023
Adiponectin receptor 1-mediated stimulation of Cav3.2 channels in trigeminal ganglion neurons induces nociceptive behaviors in mice [0.03%]
小鼠三叉神经节神经元中的载脂蛋白受体1介导的Cav3.2通道激活诱导痛觉行为
Yuan Zhang,Yuan Wei,Tingting Zheng et al.
Yuan Zhang et al.
Background: Adipokines, including adiponectin, are implicated in nociceptive pain; however, the underlying cellular and molecular mechanisms remain unknown. ...
Impact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatment [0.03%]
欧洲多国偏头痛患者的头痛频率与预防性药物失败对患者生活质量、功能和成本的影响：需要有效的预防性治疗
Dawn C Buse,Patricia Pozo-Rosich,Laure Dupont-Benjamin et al.
Dawn C Buse et al.
Background: Data are limited regarding the combined impact of headache frequency and failure of preventive medication (efficacy and/or tolerability) on the humanistic/economic burden of migraine. ...
Relationship between alcohol and primary headaches: a systematic review and meta-analysis [0.03%]
酒精与原发性头痛关系的系统评价和meta分析研究
Bartłomiej Błaszczyk,Marcin Straburzyński,Mieszko Więckiewicz et al.
Bartłomiej Błaszczyk et al.
Background: Headache is one of the most common neurological symptoms. Many previous studies have indicated a relationship between primary headaches and alcohol. Drinking has been associated with increased risk of tension-...