European Headache Federation (EHF) critical reappraisal and meta-analysis of oral drugs in migraine prevention - part 3: topiramate [0.03%]
欧洲头痛协会（EHF）对偏头痛预防口服药物的批判性再评价和meta分析（第三部分）：托吡酯
Bianca Raffaelli,David García-Azorín,Deirdre M Boucherie et al.
Bianca Raffaelli et al.
Objective: Topiramate is a repurposed first-line treatment for migraine prophylaxis. The aim of this systematic review and meta-analysis is to critically re-appraise the existing evidence supporting the efficacy and toler...
Rafael Navarro-González,David García-Azorín,Ángel L Guerrero-Peral et al.
Rafael Navarro-González et al.
Introduction: Neuroimaging has revealed that migraine is linked to alterations in both the structure and function of the brain. However, the relationship of these changes with aging has not been studied in detail. Here we...
COVID-19 vaccination-related headache showed two different clusters in the long-term course: a prospective multicenter follow-up study (COVA-Head Study) [0.03%]
一项前瞻性多中心随访研究显示新冠肺炎疫苗接种相关头痛在长期病程中表现出两种不同的类型：来自COVA-Head 研究的证据
Arife Çimen Atalar,Ayşe Nur Özdağ Acarlı,Betül Baykan et al.
Arife Çimen Atalar et al.
Background: Although acute headache following COVID-19 vaccination is widely acknowledged, the long-term progression of these headaches remains poorly understood. Our objective was to identify various phenotypes of prolon...
Observational Study
The journal of headache and pain. 2023 Sep 29;24(1):132. DOI:10.1186/s10194-023-01665-3 2023
Menstrual migraine is caused by estrogen withdrawal: revisiting the evidence [0.03%]
雌激素撤退引起月经性偏头痛：再审证据
Bianca Raffaelli,Thien Phu Do,Basit Ali Chaudhry et al.
Bianca Raffaelli et al.
Objective: To explore and critically appraise the evidence supporting the role of estrogen withdrawal in menstrual migraine. Main body: ...
Serum tau protein elevation in migraine: a cross-sectional case-control study [0.03%]
偏头痛患者血清tau蛋白水平的升高：横断面病例对照研究
Lucas Hendrik Overeem,Bianca Raffaelli,Robert Fleischmann et al.
Lucas Hendrik Overeem et al.
Background: Migraine is a disorder associated with neuropeptide release, pain and inflammation. Tau protein has recently been linked to inflammatory diseases and can be influenced by neuropeptides such as CGRP, a key neur...
Efficacy and safety of intranasal agents for the acute treatment of migraine: a systematic review and network meta-analysis [0.03%]
急性偏头痛的鼻内给药治疗效果及安全性：系统性回顾和网状meta分析
Guanglu Li,Shaojie Duan,Tiantian Zhu et al.
Guanglu Li et al.
Background: Intranasal agents may be ideal for the treatment of migraine patients. Many new acute intranasal-specific therapies have been developed, but few of them have been directly compared. The aim of this network met...
European Headache Federation (EHF) critical re-appraisal and meta-analysis of oral drugs in migraine prevention-part 2: flunarizine [0.03%]
欧洲头痛协会（EHF）对偏头痛预防的口服药物的批判性再评价和meta分析（第2部分）：氟桂利嗪
Christina I Deligianni,Simona Sacco,Esme Ekizoglu et al.
Christina I Deligianni et al.
Objective: Novel disease-specific and mechanism-based treatments sharing good evidence of efficacy for migraine have been recently marketed. However, reimbursement by insurers depends on treatment failure with classic ant...
Quality of life in children suffering from headaches: a systematic literature review [0.03%]
儿童头痛患者的生活质量：系统文献综述
S Ombashi,E Tsangaris,A G Heeres et al.
S Ombashi et al.
Background: Headaches are the most common complaints among pediatric populations. Determining the cause and appropriate treatment for headaches may be challenging and costly, and the impact of headaches on the lives of pa...
Global, regional, and national epidemiology of migraine and tension-type headache in youths and young adults aged 15-39 years from 1990 to 2019: findings from the global burden of disease study 2019 [0.03%]
1990年至2019年15至39岁青年和年轻成年人的偏头痛和肌紧张性头痛全球、区域和国家流行病学特征：来自GBD 2019的结果
Xin-Yu Li,Cheng-Hao Yang,Jia-Jie Lv et al.
Xin-Yu Li et al.
Background: In recent years, headache disorders have garnered significant attention as a pressing global health issue. This concern is especially pronounced in low- to middle-income countries and exhibits a notable increa...
Alejandro Labastida-Ramírez,Edoardo Caronna,Cédric Gollion et al.
Alejandro Labastida-Ramírez et al.
Targeting CGRP has proved to be efficacious, tolerable, and safe to treat migraine; however, many patients with migraine do not benefit from drugs that antagonize the CGRPergic system. Therefore, this review focuses on summarizing the gener...