Validity and reliability of Arabic version of pediatric migraine disability assessment scale (Child Self-Report versus Parent Proxy-Report): a multi-center study [0.03%]
儿童偏头痛残疾评定量表阿拉伯版(儿童自评与家长代报)的效度及信度:多中心研究
Rehab Magdy,Amr Hassan,Zeinab Mohammed et al.
Rehab Magdy et al.
Background: Pediatric Migraine Disability Assessment (PedMIDAS) is one of the most frequently used questionnaires to assess disability from migraine in pediatric patients. This work aimed to evaluate the validity and test...
Multicenter Study
The journal of headache and pain. 2024 Feb 5;25(1):15. DOI:10.1186/s10194-024-01713-6 2024
Real-world effectiveness of Anti-CGRP monoclonal antibodies compared to OnabotulinumtoxinA (RAMO) in chronic migraine: a retrospective, observational, multicenter, cohort study [0.03%]
在慢性偏头痛中抗CGRP单克隆抗体与肉毒杆菌素Onabot的现实效果对比(RAMO研究):一项回顾性,观察性,多中心队列研究
Licia Grazzi,Riccardo Giossi,Danilo Antonio Montisano et al.
Licia Grazzi et al.
Background: Chronic migraine (CM) is a disabling condition with high prevalence in the general population. Until the recent approval of monoclonal antibodies targeting the calcitonin gene-related peptide (Anti-CGRP mAbs),...
Observational Study
The journal of headache and pain. 2024 Feb 2;25(1):14. DOI:10.1186/s10194-024-01721-6 2024
Claudio Tana,Bianca Raffaelli,Marcio Nattan Portes Souza et al.
Claudio Tana et al.
Current definitions of migraine that are based mainly on clinical characteristics do not account for other patient's features such as those related to an impaired quality of life, due to loss of social life and productivity, and the differe...
Jakob Paungarttner,Martina Quartana,Lucrezia Patti et al.
Jakob Paungarttner et al.
Background: Migraine and epilepsy are two paroxysmal chronic neurological disorders affecting a high number of individuals and being responsible for a high individual and socioeconomic burden. The link between these disor...
Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBase® [0.03%]
妊娠期降钙素基因相关肽受体拮抗剂:VigiBase中的一个不均衡分析
Roberta Noseda,Francesca Bedussi,Claudio Gobbi et al.
Roberta Noseda et al.
Background: Current evidence on the safety of calcitonin gene-related peptide antagonists (CGRP-A) in pregnancy for the treatment of both episodic and chronic migraine is scarce and does not yet provide definitive informa...
Anti-CGRP antibody galcanezumab modifies the function of the trigeminovascular nocisensor complex in the rat [0.03%]
抗CGRP抗体galcanezumab改变大鼠三叉血管痛感受器复合体的功能
Nadine Friedrich,Krisztina Németh,Martin Tanner et al.
Nadine Friedrich et al.
Background: Monoclonal antibodies directed against the neuropeptide calcitonin gene-related peptide (CGRP) are effective in the prevention of chronic and frequent episodic migraine. Since the antibodies do not cross the b...
Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura [0.03%]
皮层快慢震荡对扩散性极化抑制效应具有不同的易感性:可能与先兆偏头痛的发病有关的状态依赖特征
Tatiana M Medvedeva,Maria P Smirnova,Irina V Pavlova et al.
Tatiana M Medvedeva et al.
Background: Spreading depolarization (SD), underlying mechanism of migraine aura and potential activator of pain pathways, is known to elicit transient local silencing cortical activity. Sweeping across the cortex, the el...
Adriana Della Pietra,Laura Gómez Dabó,Petr Mikulenka et al.
Adriana Della Pietra et al.
Background: Migraine is a debilitating neurological disorder with pain profile, suggesting exaggerated mechanosensation. Mechanosensitive receptors of different families, which specifically respond to various mechanical s...
Involvement of the ipsilateral-to-the-pain anterior-superior hypothalamic subunit in chronic cluster headache [0.03%]
慢性丛集性头痛中痛侧的前上丘脑亚单位的参与作用
Stefania Ferraro,Anna Nigri,Maria Grazia Bruzzone et al.
Stefania Ferraro et al.
Background: Despite hypothalamus has long being considered to be involved in the pathophysiology of cluster headache, the inconsistencies of previous neuroimaging studies and a limited understanding of the hypothalamic ar...
Double-blind, randomized, placebo-controlled study to evaluate erenumab-specific central effects: an fMRI study [0.03%]
评估erenumab特异性中枢效应的双盲随机安慰剂对照研究:一项fMRI研究
Hauke Basedau,Kuan-Po Peng,Marlene Schellong et al.
Hauke Basedau et al.
Objective: Given the findings of central effects of erenumab in the literature, we aimed to conduct a rigorous placebo-controlled, double-blind, randomized study to elucidate whether the observed changes are directly attr...
Randomized Controlled Trial
The journal of headache and pain. 2024 Jan 9;25(1):5. DOI:10.1186/s10194-023-01709-8 2024