Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials [0.03%]
用于预防性治疗偏头痛的阿托甘的安全性和耐受性：四项临床试验的汇总数据分析中的事后分析
Paul Rizzoli,Michael J Marmura,Jennifer Robblee et al.
Paul Rizzoli et al.
Background: Conventional, non-specific preventive migraine treatments often demonstrate low rates of treatment persistence due to poor efficacy or tolerability. Effective, well-tolerated preventive treatments are needed t...
Randomized Controlled Trial
The journal of headache and pain. 2024 Mar 11;25(1):35. DOI:10.1186/s10194-024-01736-z 2024
Decoding pain through facial expressions: a study of patients with migraine [0.03%]
通过面部表情来解码疼痛：一项偏头痛患者的研究
Wei-Ta Chen,Fu-Jung Hsiao,Gianluca Coppola et al.
Wei-Ta Chen et al.
Background: The present study used the Facial Action Coding System (FACS) to analyse changes in facial activities in individuals with migraine during resting conditions to determine the potential of facial expressions to ...
Commentary on 2022 guidelines on clinical trial design in cluster headache and further suggestions [0.03%]
2022年丛集性头痛临床试验设计指南解读及进一步建议
Ioana Medrea,Stewart J Tepper,Donliang Wang et al.
Ioana Medrea et al.
Background: New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies. ...
AMPK activation attenuates central sensitization in a recurrent nitroglycerin-induced chronic migraine mouse model by promoting microglial M2-type polarization [0.03%]
AMPK激活通过促进小胶质细胞M2型极化减轻复发性硝酸甘油诱导的慢性 migraine 鼠模型的中枢敏化
Guangshuang Lu,Shaobo Xiao,Fanchao Meng et al.
Guangshuang Lu et al.
Background: Energy metabolism disorders and neurogenic inflammation play important roles in the central sensitization to chronic migraine (CM). AMP-activated protein kinase (AMPK) is an intracellular energy sensor, and it...
The crucial role of locus coeruleus noradrenergic neurons in the interaction between acute sleep disturbance and headache [0.03%]
蓝斑去甲肾上腺素神经元在急性睡眠障碍和头痛相互作用中的重要作用
Bozhi Li,Ya Cao,Huijuan Yuan et al.
Bozhi Li et al.
Background: Both epidemiological and clinical studies have indicated that headache and sleep disturbances share a complex relationship. Although headache and sleep share common neurophysiological and anatomical foundation...
One-year prevalence of cluster headache, hemicrania continua, paroxysmal hemicrania and SUNCT in Norway: a population-based nationwide registry study [0.03%]
挪威人群中丛集性头痛、半侧颜面神经痛持续症、阵发性偏侧头痛及短间隔单侧面刺痛样头痛的年患病率-一项基于全国注册系统的研究
Knut Hagen
Knut Hagen
Background: There is lack of population-based studies evaluating the prevalence of paroxysmal hemicrania, hemicrania continua and short-lasting unilateral neuralgiform headache attacks. ...
The impact of primary headaches on disability outcomes: a literature review and meta-analysis to inform future iterations of the Global Burden of Disease study [0.03%]
原发性头痛对残疾结果的影响：文献回顾和元分析以指导疾病全球负担研究的未来迭代
Marta Waliszewska-Prosół,Danilo Antonio Montisano,Mariola Antolak et al.
Marta Waliszewska-Prosół et al.
Background: The burden and disability associated with headaches are conceptualized and measured differently at patients' and populations' levels. At the patients' level, through patient-reported outcome measures (PROMs); ...
LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion [0.03%]
长链非编码RNA Anxa10-203通过募集DHX30促进三叉神经节中Mc1r mRNA稳定性进而促进神经病理性疼痛
YaJing Liu,Fei Liu,YiKe Li et al.
YaJing Liu et al.
Background: Trigeminal nerve injury is one of the most serious complications in oral clinics, and the subsequent chronic orofacial pain is a consumptive disease. Increasing evidence demonstrates long non-coding RNAs (lncR...
Harris Poll Migraine Report Card: population-based examination of high-frequency headache/migraine and acute medication overuse [0.03%]
哈里斯民意调查关于头痛/偏头痛报告卡：基于人群的高频头痛/偏头痛和急性药物过量使用的检查
Amaal J Starling,Roger Cady,Dawn C Buse et al.
Amaal J Starling et al.
Background: Migraine is a disabling neurologic disease that can fluctuate over time in severity, frequency, and acute medication use. Harris Poll Migraine Report Card was a US population-based survey to ascertain quantifi...
Janu Thuraiaiyah,Håkan Ashina,Rune Häckert Christensen et al.
Janu Thuraiaiyah et al.
Background: Migraine is a multiphasic neurovascular disorder, where headache can be succeeded by postdromal symptoms. However, there are limited research on postdromal symptoms. This study aimed to investigate the proport...