Vascular responses to molecular migraine triggers: a systematic review of magnetic resonance angiography studies [0.03%]
分子触发因素引起的血管性偏头痛的磁共振血管造影系统评价研究
Robin Arquizan,Anna G Melchior,Rune H Christensen et al.
Robin Arquizan et al.
Objective: To synthesize and interpret magnetic resonance angiography (MRA) findings on vascular changes after administration of established molecular migraine triggers in adults with migraine and in healthy individuals, ...
Impact of migraine on productivity and efficiency among adult population in India: a scoping review [0.03%]
头痛对印度成人人口生产力和效率的影响:系统综述
S Saha,D Chowdhury,M Wadhwa et al.
S Saha et al.
Background: Migraine is a common neurological disorder that has a major negative influence on productivity loss and quality of life. Significant socioeconomic consequences are associated with the condition, such as decrea...
Compromised PGF2α signaling in the paraventricular hypothalamic nucleus contributes to the central sensitization of the nitroglycerin-induced chronic migraine in male mice [0.03%]
PVN中PGF2α信号转导受损参与了硝基甘油诱导的小鼠慢性偏头痛的中枢敏化作用
Xianrong Hu,Lunquan Wu,Li Wang et al.
Xianrong Hu et al.
Impaired descending inhibitory controls are now understood to exacerbate central sensitization of chronic migraine, yet the underlying neural and molecular mechanisms remain largely elusive. Herein, a paraventricular hypothalamic nucleus (P...
Atrophy of hypothalamic subregions increases migraine risk: cross-sectional study and mendelian randomization analysis [0.03%]
颅脑结构亚区域萎缩会增加偏头痛的风险:横断面研究与孟德尔随机化分析
Zhonghua Xiong,Lei Zhao,Geyu Liu et al.
Zhonghua Xiong et al.
Background: The hypothalamus is a versatile structure comprising several nuclei that play key roles in regulating various biological processes associated with migraine, including hormone secretion, metabolism, circadian r...
Small-molecule CGRP antagonist atogepant does not affect cortical spreading depression susceptibility in rats [0.03%]
小分子CGRP拮抗剂Atogepant不影响大鼠的皮质扩散性抑制易感性
Xuyan Jin,Andreia Morais,Yuichi Sasaki et al.
Xuyan Jin et al.
Background: Atogepant is a small-molecule non-competitive calcitonin gene-related peptide (CGRP) receptor antagonist efficacious in preventing episodic migraine. Cortical spreading depolarization (CSD) is a slowly propaga...
Volume of the hypothalamus and its subunits in patients with episodic migraine without aura during interictal periods [0.03%]
无先兆发作性偏头痛间歇期脑下垂体各子结构的体积变化研究
Irene Giardina,Antonio Di Renzo,Davide Chiffi et al.
Irene Giardina et al.
Background: The hypothalamus is thought to play a crucial role in the recurrence of migraine attacks, exhibiting activity prior to the onset of a migraine attack. Nonetheless, our comprehension of the roles of its subunit...
Pretreatment with an anti-CGRP monoclonal antibody attenuates mild TBI-induced tactile hypersensitivity in mice [0.03%]
针对CGRP的单克隆抗体可减轻轻度脑创伤诱发的小鼠触觉过敏症状
Anne-Sophie Wattiez,Adisa Kuburas,William C Castonguay et al.
Anne-Sophie Wattiez et al.
Background: Post-traumatic headache (PTH) can develop following a mild traumatic brain injury (mTBI), such as a concussion. It is especially common among active-duty military personnel, Veterans, and athletes. The high pr...
Network control theory uncovers aberrant connectome controllability in trigeminal neuralgia [0.03%]
网络控制理论揭示三叉神经痛患者异常脑网络可控性损伤
Tiantian Chu,Juan Peng,Feng Gao et al.
Tiantian Chu et al.
Background: Trigeminal neuralgia (TN) involves complex neural network alterations beyond the trigeminal system. Network Control Theory (NCT) offers a novel framework to quantify how brain network architecture constrains n...
Migraine in men - differences in phenotype and treatment patterns: results from the Migraine in Poland cross-sectional national survey [0.03%]
男性 migraine 的表型和治疗模式的差异:波兰全国性的横断面调查的结果
Marta Waliszewska-Prosół,Karol Marschollek,Sławomir Budrewicz et al.
Marta Waliszewska-Prosół et al.
Background: The 'Migraine in Poland' study is a large-scale nationwide cross-sectional online survey that assessed symptomatology, consulting, diagnosis, treatment, and burden of migraine in Poland, conducted from August ...
One-month atogepant treatment induces rapid changes in delta-band functional connectivity in migraine: an HD-EEG study [0.03%]
一项有关偏头痛的研究:一个月的atogepant治疗迅速改变了一髙密度脑电图记录到的功能连接态.delta频段动力学变化
Matteo Conti,Silvio Bagetta,Federico Carparelli et al.
Matteo Conti et al.
Background: Atogepant is a novel oral calcitonin gene-related peptide (CGRP) receptor antagonist approved for the preventive treatment of migraine. While its peripheral mechanisms are well characterized, little is known a...