Aberrant cerebral blood flow and functional connectivity in patients with vestibular migraine: a resting-state ASL and fMRI study [0.03%]
前庭性偏头痛患者异常的脑血流及功能连接：静息态动脉自旋标记和磁共振成像研究
Zhengwei Chen,Yueji Liu,Cunxin Lin et al.
Zhengwei Chen et al.
Background: Prior neuroimaging studies on vestibular migraine (VM) have extensively certified the functional and structural alterations in multiple brain regions and networks. However, few studies have assessed the cerebr...
Sustained response to atogepant in episodic migraine: post hoc analyses of a 12-week randomized trial and a 52-week long-term safety trial [0.03%]
外源性偏头痛发作对atogepant的持续反应：一项12周随机试验和一项52周长期安全试验的事后分析
Richard B Lipton,Stephanie J Nahas,Patricia Pozo-Rosich et al.
Richard B Lipton et al.
Background: Atogepant is an oral calcitonin gene-related peptide receptor antagonist approved for the preventive treatment of migraine in adults. These analyses evaluated the proportions of clinical trial participants who...
Randomized Controlled Trial
The journal of headache and pain. 2024 May 21;25(1):83. DOI:10.1186/s10194-024-01783-6 2024
Alleviation of migraine related pain and anxiety by inhibiting calcium-stimulating AC1-dependent CGRP in the insula of adult rats [0.03%]
通过抑制成人大鼠岛叶AC1依赖的CGRP介导的钙离子刺激来缓解偏头痛相关的疼痛和焦虑
Yang Li,Chenhao Li,Qi-Yu Chen et al.
Yang Li et al.
Background: Recent animal and clinical findings consistently highlight the critical role of calcitonin gene-related peptide (CGRP) in chronic migraine (CM) and related emotional responses. CGRP antibodies and receptor ant...
Poor healthy lifestyle and life's essential 8 are associated with higher risk of new-onset migraine: a prospective cohort study [0.03%]
不良的健康生活方式与新发偏头痛风险增加有关：前瞻性队列研究
Yuexiu Lei,Lili Zhang,Zhengming Shan et al.
Yuexiu Lei et al.
Background: Lifestyle are closely related to migraine. However, there is a lack of studies investigating the association between Healthy lifestyle or Life's Essential 8 (LE8) and the risk of migraine. The objective of thi...
MicroRNA profiling in women with migraine: effects of CGRP-targeting treatment [0.03%]
偏头痛女性患者的微小核糖核酸谱分析：降钙素基因相关肽靶向治疗的影响
Raffaele Ornello,Veronica Zelli,Chiara Compagnoni et al.
Raffaele Ornello et al.
Background: Migraine lacks biomarkers that can trace the biological pathways of the disease and predict the effectiveness of treatments. Monoclonal antibodies targeting calcitonin gene-related peptide pathway - including ...
Effectiveness and tolerability of eptinezumab in treating patients with migraine resistant to conventional preventive medications and CGRP (receptor) antibodies: a multicentre retrospective real-world analysis from Germany [0.03%]
德国多中心真实世界分析：对于对传统预防药物和CGRP（受体）抗体耐药的 migraine 患者，eptinezumab的有效性和耐受性
Armin Scheffler,Pauline Wenzel,Merle Bendig et al.
Armin Scheffler et al.
Background: Eptinezumab is a monoclonal antibody that targets calcitonin gene-related peptide (CGRP mAb) and is used for migraine prophylaxis. Efficacy data are mainly from clinical trials, real-world data are hardly avai...
Multicenter Study
The journal of headache and pain. 2024 May 16;25(1):79. DOI:10.1186/s10194-024-01788-1 2024
Migraine or any headaches and white matter hyperintensities and their progression in women and men [0.03%]
migraine或头痛以及高灌注白质异常及进展（女性和男性）
Sara Helena Schramm,I Tenhagen,M Jokisch et al.
Sara Helena Schramm et al.
Background: Cross-sectional and longitudinal studies have been conducted to investigate the association between migraine and any headache and white matter hyperintensities (WMH). However, studies are inconsistent regardin...
Does pain self-efficacy predict, moderate or mediate outcomes in people with chronic headache; an exploratory analysis of the CHESS trial [0.03%]
一项探索性分析：疼痛自我效能能否预测、调节或中介慢性头痛患者的预后；CHESS试验数据
Siew Wan Hee,Shilpa Patel,Harbinder Sandhu et al.
Siew Wan Hee et al.
Background: Chronic headache disorders are disabling. The CHESS trial studied the effects of a short non-pharmacological intervention of education with self-management support for people affected by migraine and/or tensio...
Deciphering the functional role of insular cortex stratification in trigeminal neuropathic pain [0.03%]
解读岛叶皮层分层在三叉神经痛功能作用中的作用
Jaisan Islam,Md Taufiqur Rahman,Elina Kc et al.
Jaisan Islam et al.
Trigeminal neuropathic pain (TNP) is a major concern in both dentistry and medicine. The progression from normal to chronic TNP through activation of the insular cortex (IC) is thought to involve several neuroplastic changes in multiple bra...
Extrasynaptic δGABAA receptors mediate resistance to migraine-like phenotype in rats [0.03%]
外突触δGABAA受体介导抵抗类似偏头痛的表型在大鼠模型中的作用研究
Berkay Alpay,Bariscan Cimen,Elif Akaydin et al.
Berkay Alpay et al.
Background: GABA, a key inhibitory neurotransmitter, has synaptic and extrasynaptic receptors on the postsynaptic neuron. Background GABA, which spills over from the synaptic cleft, acts on extrasynaptic delta subunit con...