Exploring potential neuroimaging biomarkers for the response to non-steroidal anti-inflammatory drugs in episodic migraine [0.03%]
探讨偏头痛发作患者对非甾体抗炎药反应的潜在神经影像生物标志物
Heng-Le Wei,Yu-Sheng Yu,Meng-Yao Wang et al.
Heng-Le Wei et al.
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are considered first-line medications for acute migraine attacks. However, the response exhibits considerable variability among individuals. Thus, this study aime...
Connectivity of the insular subdivisions differentiates posttraumatic headache-associated from nonheadache-associated mild traumatic brain injury: an arterial spin labelling study [0.03%]
基于动脉自旋标记的轻度脑外伤患者岛叶亚区连接性的改变及其在头痛中的作用
Fengfang Li,Di Zhang,Jun Ren et al.
Fengfang Li et al.
Objective: The insula is an important part of the posttraumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) neuropathological activity pattern. It is composed of functionally different subdivisions and...
Occurrence of new or more severe headaches following COVID-19 is associated with markers of microglial activation and peripheral sensitization: results from a prospective cohort study [0.03%]
一项前瞻性队列研究的结果：COVID-19后出现新的或更严重的头痛与小胶质细胞活化和外周敏化的标志物有关
Johanna Ruhnau,Max Blücher,Susanne Bahlmann et al.
Johanna Ruhnau et al.
Background: New onset or worsening of a headache disorder substantially contributes to the disease burden of post-COVID-19. Its management poses a suitable means to enhance patients' participation in professional, social,...
Hypersensitivity to BKCa channel opening in persistent post-traumatic headache [0.03%]
BKCa通道开放过度敏感在持续性创伤后头痛中的作用
Haidar M Al-Khazali,Rune H Christensen,David W Dodick et al.
Haidar M Al-Khazali et al.
Background: Large conductance calcium-activated potassium (BKCa) channels have been implicated in the neurobiological underpinnings of migraine. Considering the clinical similarities between migraine and persistent post-t...
Randomized Controlled Trial
The journal of headache and pain. 2024 Jun 18;25(1):102. DOI:10.1186/s10194-024-01808-0 2024
Identifying therapeutic target genes for migraine by systematic druggable genome-wide Mendelian randomization [0.03%]
基于孟德尔随机化的全基因组范围可用药性分析鉴定偏头痛的治疗靶点基因
Chengcheng Zhang,Yiwei He,Lu Liu
Chengcheng Zhang
Background: Currently, the treatment and prevention of migraine remain highly challenging. Mendelian randomization (MR) has been widely used to explore novel therapeutic targets. Therefore, we performed a systematic drugg...
Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine [0.03%]
episodic偏头痛患者边缘系统和感觉系统的结构连接组变化
Eunchan Noh,Jong Young Namgung,Yeongjun Park et al.
Eunchan Noh et al.
Migraine is a complex neurological condition characterized by recurrent headaches, which is often accompanied by various neurological symptoms. Magnetic resonance imaging (MRI) is a powerful tool for investigating whole-brain connectivity p...
PACAP-38 and sex hormones in women with migraine: exploratory analysis of a cross-sectional, matched cohort study [0.03%]
促肾上腺皮质激素释放肽和性激素与女性偏头痛的相关性：一项匹配队列研究的探索性分析
Elisabeth Storch,Lucas H Overeem,Maria Terhart et al.
Elisabeth Storch et al.
Background: Endogeneous and exogeneous sex hormones can impact the frequency and severity of migraine attacks, but the underlying mechanisms are poorly understood. In this study, we investigate the relationship between fe...
Longitudinal neurofunctional changes in medication overuse headache patients after mindfulness practice in a randomized controlled trial (the MIND-CM study) [0.03%]
一项随机对照试验（MIND-CM研究）中正念练习后药物过量性头痛患者纵向神经功能变化的研究
Davide Fedeli,Giuseppe Ciullo,Greta Demichelis et al.
Davide Fedeli et al.
Background: Mindfulness practice has gained interest in the management of Chronic Migraine associated with Medication Overuse Headache (CM-MOH). Mindfulness is characterized by present-moment self-awareness and relies on ...
Woo-Seok Ha,Min Kyung Chu
Woo-Seok Ha
Background: The pathogenesis of migraine remains unclear; however, a large body of evidence supports the hypothesis that immunological mechanisms play a key role. Therefore, we aimed to review current studies on altered i...
Global, regional, and national burden and trends of migraine among women of childbearing age from 1990 to 2021: insights from the Global Burden of Disease Study 2021 [0.03%]
1990年至2021年全球、区域和国家育龄女性偏头痛疾病负担和趋势：来自2021年全球疾病负担研究的见解
Jing Cen,Qian Wang,Lin Cheng et al.
Jing Cen et al.
Background: Migraine, a neurological disorder with a significant female predilection, is the leading cause of disability-adjusted life years (DALYs) in women of childbearing age (WCBA). There is currently a lack of compre...