Unveiling a groundbreaking alliance: the inaugural collaboration between the Asian Regional Consortium of Headache and The Journal of Headache and Pain [0.03%]
亚洲头痛区域联盟与《头痛和疼痛杂志》首次合作启动仪式
Tissa Wijeratne,Surat Tanprawate,Lakshman Singh et al.
Tissa Wijeratne et al.
Unraveling the interplay of neuroinflammatory signaling between parenchymal and meningeal cells in migraine headache [0.03%]
解开神经炎症信号在偏头痛中的作用：皮质细胞和脑膜细胞的相互影响
Turgay Dalkara,Zeynep Kaya,Şefik Evren Erdener
Turgay Dalkara
Background: The initiation of migraine headaches and the involvement of neuroinflammatory signaling between parenchymal and meningeal cells remain unclear. Experimental evidence suggests that a cascade of inflammatory sig...
The role of hypertension in the relationship between leisure screen time, physical activity and migraine: a 2-sample Mendelian randomization study [0.03%]
高血压在休闲屏幕时间、身体活动和偏头痛关系中的作用：两项样本孟德尔随机化研究
Quan Gan,Enfeng Song,Lily Zhang et al.
Quan Gan et al.
Background: The relationship between lifestyle and migraine is complex, as it remains uncertain which specific lifestyle factors play the most prominent role in the development of migraine, or which modifiable metabolic t...
European Headache Federation (EHF) critical re-appraisal and meta-analysis of oral drugs in migraine prevention - part 4: propranolol [0.03%]
欧洲头痛联合会（EHF）偏头痛预防口服药物的批判性再评价和荟萃分析第4部分：心得安
Jan Versijpt,Christina Deligianni,Muizz Hussain et al.
Jan Versijpt et al.
Objective: The aim of this paper is to critically re-appraise the published trials assessing propranolol for migraine prophylaxis. Methods: ...
Elevated cytokine levels in the central nervous system of cluster headache patients in bout and in remission [0.03%]
发作期和缓解期丛集性头痛患者中枢神经系统的细胞因子水平升高
Caroline Ran,Felicia Jennysdotter Olofsgård,Katrin Wellfelt et al.
Caroline Ran et al.
Background: Cluster headache is characterized by activation of the trigeminovascular pathway with subsequent pain signalling in the meningeal vessels, and inflammation has been suggested to play a role in the pathophysiol...
The effect of P2X7 antagonism on subcortical spread of optogenetically-triggered cortical spreading depression and neuroinflammation [0.03%]
P2X7抗炎药对光遗传学触发的皮层扩散抑制向皮层下结构传播及神经炎症的影响研究
Burak Uzay,Buket Donmez-Demir,Sinem Yilmaz Ozcan et al.
Burak Uzay et al.
Migraine is a neurological disorder characterized by episodes of severe headache. Cortical spreading depression (CSD), the electrophysiological equivalent of migraine aura, results in opening of pannexin 1 megachannels that release ATP and ...
Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential drug target for migraine [0.03%]
整合GWAS、eQTL和pQTL数据的多组学孟德尔随机化研究揭示GSTM4为偏头痛的潜在药物靶点
Xinyue Sun,Bohong Chen,Yi Qi et al.
Xinyue Sun et al.
Introduction: Migraine, as a complex neurological disease, brings heavy burden to patients and society. Despite the availability of established therapies, existing medications have limited efficacy. Thus, we aimed to find...
Abnormally glymphatic system functional in patients with migraine: a diffusion kurtosis imaging study [0.03%]
弥散张量成像在偏头痛患者中的应用研究
Yungang Cao,Mei Huang,Fangwang Fu et al.
Yungang Cao et al.
Background: The diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) method has been used to evaluate glymphatic system function in patients with migraine. However, since the diffusion tensor model ca...
Efficacy and safety of atogepant, a small molecule CGRP receptor antagonist, for the preventive treatment of migraine: a systematic review and meta-analysis [0.03%]
阿托杰潘治疗偏头痛有效性和安全性的系统评价和网络meta分析
Min Hou,Xiaofeng Luo,Shuangshuang He et al.
Min Hou et al.
Background: Migraine is one of the most common diseases worldwide while current treatment options are not ideal. New therapeutic classes of migraine, the calcitonin gene-related peptide (CGRP) antagonists, have been devel...
Inhibition of 2-AG hydrolysis alleviates posttraumatic headache attributed to mild traumatic brain injury [0.03%]
2-AG水解抑制可缓解轻度创伤性脑损伤所致的外伤后头痛
Jie Wen,Mikiei Tanaka,Yumin Zhang
Jie Wen
Background: Posttraumatic headache (PTH) is a common and debilitating symptom following repetitive mild traumatic brain injury (rmTBI), and it mainly resembles a migraine-like phenotype. While modulation of the endocannab...