Phasic perfusion dynamics among migraine subtypes: a multimodel arterial spin labeling investigation [0.03%]
偏头痛亚型的阶段性灌注动力学：动脉自旋标记多模式研究
Chia-Hung Wu,Pei-Lin Lee,Yen-Feng Wang et al.
Chia-Hung Wu et al.
Background: Migraine-related perfusion changes are documented but inconsistent across studies due to limited sample size and insufficient phenotyping. The phasic and spatial dynamics across migraine subtypes remains poorl...
Effects of passive smoking on cortical spreading depolarization in male and female mice [0.03%]
环境烟雾对小鼠皮层扩散去极化的影响
Tsubasa Takizawa,Keiko Ihara,Miyuki Unekawa et al.
Tsubasa Takizawa et al.
Background: Patients with migraine are typically advised to avoid passive smoking because it may aggravate headaches and other health conditions. However, there is insufficient high-quality evidence on the association bet...
Household income is associated with attack frequency, but not with the prevalence of headache: an analysis of self-reported headache in the general population in Germany [0.03%]
家庭收入与头痛发作频率但与患病率无关：基于德国一般人群的自我报告式分析
Britta Müller,Charly Gaul,Olaf Reis et al.
Britta Müller et al.
Background: Headache disorders are among the most prevalent neurological disorders worldwide. However, whether groups differing in socioeconomic position (SEP) are disproportionately affected by headache disorders has not...
1H-MRS reveals abnormal energy metabolism and excitatory-inhibitory imbalance in a chronic migraine-like state induced by nitroglycerin in mice [0.03%]
1H-MRS揭示硝酸甘油诱导的小鼠慢性偏头痛样状态下的异常能量代谢和兴奋性-抑制失衡
Jinggui Gao,Da Wang,Chenlu Zhu et al.
Jinggui Gao et al.
Background: Chronic migraine is closely related to the dysregulation of neurochemical substances in the brain, with metabolic imbalance being one of the proposed causes of chronic migraine. This study aims to evaluate the...
Characteristics of locus coeruleus functional connectivity network in patients with comorbid migraine and insomnia [0.03%]
合并偏头痛和失眠患者的蓝斑功能连接网络特征分析
Changlin Wang,Sishi Chen,Zihan Cheng et al.
Changlin Wang et al.
Background: Migraine and insomnia are prevalent conditions that often co-occur, each exacerbating the other and substantially impacting the quality of life. The locus coeruleus (LC), a brainstem region responsible for nor...
First real-world study on the effectiveness and tolerability of rimegepant for acute migraine therapy in Chinese patients [0.03%]
中国患者急性偏头痛治疗中瑞美吉泮的有效性和耐受性的首次真实世界研究
Zhao Yang,Xiaodan Wang,Mengyue Niu et al.
Zhao Yang et al.
Background: Rimegepant, a small molecule calcitonin gene-related peptide (CGRP) receptor antagonist, is indicated for acute and preventive migraine treatment in the United States and other countries. However, there is a l...
Epidemiological linkage between migraine and diabetes mellitus: a systematic review and meta-analysis [0.03%]
偏头痛与糖尿病之间流行病学联系的系统评价和meta分析
Woo-Seok Ha,Vinh Khang Nguyen,Min Kyung Chu
Woo-Seok Ha
Background: This study aimed to elucidate the nature and extent of the associations between diabetes mellitus (DM) and migraine through a systematic review and meta-analysis. ...
Dora Torok,Peter Petschner,Daniel Baksa et al.
Dora Torok et al.
Background: Recent meta-analyses estimated 14.6% and 11.2% SNP-based heritability of migraine, compared to twin-heritability estimates of 30-60%. This study aimed to investigate heritability estimates in "migraine-first" ...
Assessment of prolonged safety and tolerability of erenumab in migraine patients in a long-term open-label study (APOLLON) [0.03%]
一项长期开放标签研究（APOLLON）评估偏头痛患者使用erenumab长期安全性和耐受性的研究
Hartmut Göbel,Eugen Schlegel,Kathrin Jaeger et al.
Hartmut Göbel et al.
Background: Efficacy and safety of human monoclonal antibody erenumab used for migraine prophylaxis have been shown in clinical studies. APOLLON is an open-label, multi-center, single arm study, which permits dose adjustm...
Targeting IGF1/IGF1r signaling relieve pain and autophagic dysfunction in NTG-induced chronic migraine model of mice [0.03%]
靶向IGF1/IGF1R信号减轻NTG诱导的小鼠慢性偏头痛模型的疼痛和自噬功能障碍
Tianxiao Wang,Chenlu Zhu,Kaibo Zhang et al.
Tianxiao Wang et al.
Background: Chronic migraine is a severe and common neurological disorder, yet its precise physiological mechanisms remain unclear. The IGF1/IGF1r signaling pathway plays a crucial role in pain modulation. Studies have sh...