Machine learning classification meets migraine: recommendations for study evaluation [0.03%]
机器学习分类与偏头痛：研究评估建议
Igor Petrušić,Andrej Savić,Katarina Mitrović et al.
Igor Petrušić et al.
The integration of machine learning (ML) classification techniques into migraine research has offered new insights into the pathophysiology and classification of migraine types and subtypes. However, inconsistencies in study design, lack of...
Lanfranco Pellesi,David Garcia-Azorin,Eloisa Rubio-Beltrán et al.
Lanfranco Pellesi et al.
Combination treatments for migraine prophylaxis present a promising approach to addressing the diverse and complex mechanisms underlying migraine. This review explores the potential of combining oral conventional prophylactics, onabotulinum...
Resistant and refractory migraine - two different entities with different comorbidities? Results from the REFINE study [0.03%]
抗药性和难治性偏头痛-两种不同疾病并伴有不同合并症？REFINE研究结果
C Rosignoli,R Ornello,V Caponnetto et al.
C Rosignoli et al.
Background: Resistant and refractory migraine are commonly encountered in specialized headache centers. Several comorbidities, mostly psychiatric conditions, have been linked to migraine worsening; however, there is littl...
Observational Study
The journal of headache and pain. 2024 Dec 3;25(1):212. DOI:10.1186/s10194-024-01910-3 2024
Elevated plasma CXCL12 leads to pain chronicity via positive feedback upregulation of CXCL12/CXCR4 axis in pain synapses [0.03%]
升高的血浆CXCL12通过疼痛突触中正反馈调节的CXCL12 / CXCR4轴导致慢性疼痛
Shi-Ze Leng,Mei-Jia Fang,Yi-Min Wang et al.
Shi-Ze Leng et al.
Background: Chronic pain poses a clinical challenge due to its associated costly disability and treatment needs. Determining how pain transitions from acute to chronic is crucial for effective management. Upregulation of ...
Cluster headache and galcanezumab: the first real-world Brazilian study and an expert consensus on its use among other treatments [0.03%]
巴西第一项真实世界研究：群集性头痛和galcanezumab以及该药与其他疗法联用的专家共识意见
Abouch Krymchantowski,Carla Jevoux,Élcio Juliato Piovesan et al.
Abouch Krymchantowski et al.
Objective: To present the first Brazilian real-world results with galcanezumab and provide a consensus expert opinion on the prophylactic treatment of cluster headache (CH) in Brazil. ...
Observational Study
The journal of headache and pain. 2024 Dec 3;25(1):211. DOI:10.1186/s10194-024-01909-w 2024
Efficacy and safety profile of Onabotulinum toxin-A injection at sphenopalatine ganglion in trigeminal neuralgia: a prospective observational study [0.03%]
肉毒杆菌毒素A注射至翼腭神经节治疗三叉神经痛的疗效和安全性：一项前瞻性观察研究
Marvin Thepsoparn,Prakit Anukoolwittaya,Patcharapol Toeypromthong et al.
Marvin Thepsoparn et al.
Introduction: The sphenopalatine ganglion (SPG) plays a role in orofacial pain and headaches and is a target for pain modulation. Onabotulinum toxin-A injections have been described as a treatment for several neuropathic ...
Observational Study
The journal of headache and pain. 2024 Dec 2;25(1):210. DOI:10.1186/s10194-024-01926-9 2024
The burden of headache disorders among adults in Peru: national estimates and a health-care needs assessment from a population-based door-to-door survey [0.03%]
秘鲁成年人头痛障碍的负担：一项基于人口的入户调查估算及医疗需求评估
Guiovanna Quispe,Cesar Loza,Luis Limaco et al.
Guiovanna Quispe et al.
Background: We have previously found that almost two thirds (64.6%) of adults in Peru have an active headache disorder. Here, using data from the same sample, we present attributed burden at individual and population leve...
Impact of migraine on changes in cardiovascular health profile among Hong Kong Chinese women: insights from the MECH-HK cohort study [0.03%]
香港女性头痛对心血管健康状况变化的影响：来自MECH-HK队列研究的见解
Jingbo Liang,Jia-Jun Ma,Harry Haoxiang Wang et al.
Jingbo Liang et al.
Background: Previous research has shown an association between migraine and cardiovascular diseases (CVDs). However, limited studies have explored the progression of cardiovascular health (CVH) among individuals with migr...
Potential hypothalamic mechanisms in trigeminal neuropathic pain: a comparative analysis with migraine and cluster headache [0.03%]
三叉神经病理性疼痛的下丘脑潜在机制与偏头痛和丛集性头痛的比较分析
Jaisan Islam,Md Taufiqur Rahman,Muhammad Ali et al.
Jaisan Islam et al.
Trigeminal neuropathic pain (TNP), migraine, and cluster headache (CH) profoundly impact the quality of life and present significant clinical challenges due to their complex neurobiological underpinnings. This review delves into the pivotal...
Real-world study of adverse events associated with triptan use in migraine treatment based on the U.S. Food and Drug Administration (FDA) adverse event reporting system (FAERS) database [0.03%]
基于美国食品药品监督管理局不良事件通报系统数据库的偏头痛治疗中曲普坦药物相关不良事件的真實世界研究
Wen-Hui Liu,Hui-Min Hu,Chen Li et al.
Wen-Hui Liu et al.
Background: Triptans selectively agoniste 5-Hydroxytryptamine(5-HT) receptors and are widely used in the treatment of migraine. Nevertheless, there is a dearth of comprehensive real-world clinical research on the safety o...